Evolution of vertebrate blood vessels
Dr T Takahashi, Dr S Herbert
Applications accepted all year round
The blood vessels are the core elements of the circulatory system of animals, and their malfunction is related to most human diseases including cancer and heart attacks.
Study of pioneer transcription factor dynamics during vertebrate Zygotic Genome Activation
MRC Human Genetics Unit
Dr D Papadopoulos
18 January 2019
How do transcription factors (TFs) regulate development at the correct time, dosage and place? How do they “know” how to “find” their target sites in live cells, with ultimate precision and specificity? Many developmental disorders are caused by haploinsufficiencies of TFs, thus their concentration and molecular behaviour is critical for directing correct embryonic development.