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viral PhD Projects, Programmes & Scholarships
We have 85 viral PhD Projects, Programmes & Scholarships
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Phase transitions underlying viral replication: understanding the selectivity of viral replication factories through the lens of biomolecular condensates
There is an urgent need for new drugs to combat pathogenic viruses. Most existing antivirals inhibit virus attachment/entry or target key enzymes, and new antiviral targets are needed to develop novel treatments and counter antiviral resistance. Read more
Face off – Dissecting the role of phase separation in viral replication and antiviral responses
Background. The assembly of membraneless organelles is emerging as a fundamental paradigm for many cellular functions. Among these, stress granules (SGs) play a central role in health and disease by concentrating proteins and RNAs, driving adaption to stressful conditions, including viral infection. Read more
Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
Identification and characterisation of novel flavivirus protease cleavages sites in mammalian and insect cells using N-terminomics
Positive sense single stranded RNA viruses translate their large open reading frames as a polyprotein that is cleaved by viral and/or host proteases to release mature viral proteins. Read more
Probing Viral Receptor-Glycan Interactions using Polyvalent Multifunctional Glycan-Nanoparticle
Research Group:
School of Chemistry
Multivalent viral receptor-glycan interactions are central to viral infection and immune response regulation. However, the underpinning structural mechanisms are often poorly understood, due to a lack of effective probes for such complex, multimeric and flexible proteins. Read more
Identifying the impact of genetic variants of MICB associated with severe and symptomatic dengue virus infection on NK and CD8+ T cell function
Supervisors. Dr Laura Rivino (Bristol, lead supervisor), Dr Edward Wang (Cardiff), Dr Richard Stanton (Cardiff), Prof Nicholas Timpson (Bristol), Dr Sophie Yacoub (Oxford University Clinical Research Unit, HCMC, Vietnam). Read more
How do viral capsids subvert host defences and deliver viral genomes into the host cell nucleus?
Seeking a curious PhD student to join our interdisciplinary Structural Virology and Molecular. Machines group at the EMBL Australia Node in Single Molecule Science (SMS) at UNSW Sydney. Read more
Viral regulation of host cell DNA damage response pathways
Human adenoviruses are small non-enveloped viruses and possess a linear, double-stranded DNA genome. Adenovirus has long been used as a tool to dissect the molecular basis of key biological processes such as growth, differentiation and death. Read more
MSc by Research: Identification of a serum-transferrable factor in helminth infections that prevents respiratory viral infection
In the developing world, parasitic helminths infect a large proportion of the population – up to 1 billion people are infected with soil-transmitted helminth (STH) infections worldwide. Read more
Computational modelling of viral proteins for improved prediction of virus-host pairs
This is a challenging but exciting opportunity for a motivated PhD candidate to contribute to the development and evaluation of novel approaches for host-virus (incl. Read more
Investigation of salivary peptides as SARS-CoV-2 entry inhibitors
The global pandemic caused by the emergence of a novel Coronavirus in Wuhan during 2019 has had a huge impact on all aspects of human health. Read more
The innate immune response to respiratory viral infection in diabetes: is glucose control the key?
Department of Infectious Diseases| Faculty of Medicine. . 3-year funded PhD position. The innate immune response to respiratory viral infection in diabetes. Read more
MSc by Research: Regulation of T cell function by SIK3 in viral infection
T cells play critical roles in the host response to viral infection. Activated cytotoxic CD8 T cells are able to kill virally infected cells while… Read more
The Creation of Anti-Viral Plastic Nanobodies for Diagnostics and Therapeutics via Molecular Imprinting of Synthetic Polymers
Overview. The need to quickly generate new diagnostic tools and therapies in the battle against viral diseases has been highlighted recently by the continuing global pandemic caused by the SARS-CoV-2 virus. Read more