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virulence PhD Projects, Programmes & Scholarships

We have 25 virulence PhD Projects, Programmes & Scholarships

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We have 25 virulence PhD Projects, Programmes & Scholarships

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Structural and biological characterisation of virulence factor in Gram-negative pathogens affecting aquaculture

Gram-negative pathogens are responsible for major disease problems in humans and animals, and a better understanding of the mechanisms for how these bacteria cause infections is key to identifying more effective ways to prevent and treat outbreaks. Read more
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Understanding the role of fungal effector proteins in antagonistic fungus–microbe interactions

Background. Fungi secrete a collection of proteins to their surrounding environments. In the case of plant-pathogenic fungi, many of these proteins are virulence factors, termed effectors, which function to promote host colonization through the modulation of plant physiology or immunity1. Read more

Understanding the commensal-to-pathogen transition – environmental cues and signalling cascades

Summary. The yeast Candida albicans is a common commensal of the human gastrointestinal tract. Using a combination of microbiology, molecular biology, protein biochemistry and proteomics methods, this project aims to define the role of a Hsp90 phospho-switch . Read more

Targeting the control of antimicrobial efflux in Mycobacterium tuberculosis to combat MDR-TB

We need more drugs for tuberculosis (TB), particularly multi-drug resistant (MDR) TB. TB treatment length (currently up to 24 months) needs to be shortened by using more effective drug combinations. Read more

Developing gregarine apicomplexans as aquatic symbiosis model system

The Gordon and Betty Moore Foundation’s Symbiosis in Aquatic Systems Initiative, seeks to advance the understanding of aquatic symbioses that include microbial partners. Read more
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Ultrastructural insights into avian herpesvirus-host cell interactions

Marek’s disease virus (MDV) is a major avian alphaherpesvirus associated with Marek’s disease (MD) in poultry characterised by rapid-onset T-cell lymphomas, immunosuppression and paralysis causing annual economic losses of around $2 billion worldwide. Read more

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