Campylobacter jejuni is the major causative agent of foodborne gastroenteritis across Europe. Contaminated chicken meat is the main source of infections and hence control of this pathogen is critical to food security in the poultry industry.
Pseudomonas aeruginosa is an important opportunistic pathogen. It is a problem for the immunocompromised and has attained superbug notoriety since it is evident in hospitals and has inherent resistance to antibiotics.
The African trypanosome, Trypanosoma brucei, is transmitted among mammalian hosts by tsetse flies. These unicellular parasites cause sleeping sickness or Human African Trypanosomiasis, typically fatal if left untreated, and the livestock disease known as nagana.
Tuberculosis remains a major global threat as it affects humans and production animals. Mycobacterium tuberculosis and Mycobacterium bovis, the causative agents of tuberculosis in human and animals, are highly successful pathogens which secrete multiple virulence factors.
Mycolic acid-producing actinomycetes are of vital economic and medical importance. They include pathogenic species including Corynebacterium diphtheriae, Mycobacterium tuberculosis and Rhodococcus equi as well as industrially important organisms.