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virulence PhD Projects, Programmes & Scholarships
We have 38 virulence PhD Projects, Programmes & Scholarships
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CRISPR/Cas9 probing of virulence factors in dermatophytes
One of the most widespread fungal infections affecting 20-25% of the global population is dermatophytosis. This is caused by fungi that infect the skin, nails, and hair, leading to common conditions such as athlete’s foot or ringworm. Read more
EASTBIO: How does the human fungal pathogen, Candida albicans, exploit its metabolic flexibility to enhance virulence?
Research Group:
Infection Medicine
Fungal pathogens kill over a million people every year. The most common human fungal pathogen is Candida albicans, a WHO-priority target. Read more
Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.
We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria. Read more
MSc by Research: Understanding temperature-dependent virulence regulation in bacterial pathogens
Bacterial pathogens respond rapidly to environmental change, in ways that can influence their growth, virulence, antimicrobial resistance and, therefore, infection outcomes. Read more
Antimicrobial resistance and gene regulation in Enteroaggregative Escherichia coli.
Enteroaggregative Escherichia coli (EAEC) is a major cause of diarrhoeal disease in industrialized and non-industrialized countries and has been shown to be the cause of travellers’ diarrhoea and persistent diarrhoea in children and HIV patients. Read more
White Rose BBSRC DTP: New secreted virulence factors from Phytophthora infestans
Phytophthora infestans, also known as potato late blight, stands as one of the most formidable oomycete pathogens in agriculture, inflicting economic damage surpassing $6 billion every year. Read more
Fully-funded White Rose BBSRC DTP Biology project: New secreted virulence factors from Phytophthora infestans
Lead supervisor. Dr Federico Sabbadin. Co-supervisors. Prof Katherine Denby. The student will be registered with the Department of Biology. Read more
Host-pathogen interactions: mechanisms of bacterial effector protein interference with host cell signalling
Talented and motivated students, passionate about doing research, are invited to apply for this PhD position. The successful applicant will join the Crick PhD Programme in September 2024 and will register for their PhD at one of the Crick partner universities (Imperial College London, King’s College London or UCL). Read more
Implementation of long-read technologies to detect genetic determinants of phenotypic variation in disease and carriage isolate of a bacterial pathogen
Wellcome Trust DTP in Genomic Epidemiology and Public Health Genomics. Neisseria meningitidis is the major cause of bacterial meningitis but is also widespread as an asymptomatic coloniser of human oropharyngeal tissues. Read more
Understanding the interplay of biofilm growth and AMR plasmid conjugation
Research interests/description of main research theme. Background. Antimicrobial resistance (AMR) is a major crisis for human medicine. Read more
Evolution of antimicrobial resistance in bacterial microbiomes
This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 20 studentships for entry in September 2024. Read more
Host-pathogen interactions of the Cryptosporidium parasite
Talented and motivated students, passionate about doing research, are invited to apply for this PhD position. The successful applicant will join the Crick PhD Programme in September 2024 and will register for their PhD at one of the Crick partner universities (Imperial College London, King’s College London or UCL). Read more
White Rose BBSRC DTP: Elucidating the molecular mechanisms of periplasmic chaperones in gram-negative bacteria: Novel targets to combat antimicrobial resistance
Antibiotic resistance is projected to cause 10 million deaths p.a. by 2050, with gram-negative pathogens comprising 9 of the 12 bacteria that pose the greatest threat. Read more
Host-pathogen interactions of bacterial membrane proteins
In this age of increasing antimicrobial resistance, bacterial infections remain a major global health burden. During infection, bacterial pathogens deliver virulence proteins into the host cells. Read more
GW4 BioMed2 MRC DTP PhD project: Developing new weapons to fight drug-resistant superbugs – targeting lipoteichoic acid biosynthesis
This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 20 studentships for entry in September 2024. Read more