Maintenance and regulation of virulence in Shigella
Prof C Tang
11 January 2019
Shigella is a leading cause of bacillary dysentry worldwide. The bacterium invades intestinal epithelial cells by virtue of a specialised secretion system, the T3SS, which is encoded on a large virulence plasmid.
Secretion of virulence determinants from Gram negative bacteria
Dr S MacIntyre
Applications accepted all year round
The outer membrane (OM) of Gram negative bacteria is the interface between the bacterial cell and the environment. Many important virulence determinants of pathogenic bacteria are either embedded in this membrane or secreted across the membrane.