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virulence PhD Projects, Programs & Scholarships

We have 42 virulence PhD Projects, Programs & Scholarships

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  Genotype-to-structure: analysis of the glycosylation of the flagella of Campylobacter jejuni, a major cause of food-borne gastroenteritis
University of Leicester Department of Genetics and Genome Biology
  Dr C D Bayliss, Prof J Ketley
Application Deadline: 5 May 2019
Campylobacter jejuni is the major causative agent of foodborne gastroenteritis across Europe. Contaminated chicken meat is the main source of infections and hence control of this pathogen is critical to food security in the poultry industry.
Details
Type/Funding
  Identification of colistin resistant gene, mcr-1, in clinical isolated Enterobacteriaceae and characterisation of pathogenicity and virulence of mcr-1 harboured bacterial pathogens
University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
  Dr C Chang, Dr J N Fletcher
Applications accepted all year round
Globally, infectious disease accounts for more than 13 million deaths a year and is one of the main causes of death around the world, predominantly in developing countries.
Details
Type/Funding
  To experimentally determine the environmental influences acting on P. aeruginosa virulence factor expression in biofilms and understand the catalytic mechanism of one of them (the surface tethered aminopeptidase AaaA)
University of Nottingham School of Life Sciences
  Dr K Hardie
Applications accepted all year round
Pseudomonas aeruginosa is an important opportunistic pathogen. It is a problem for the immunocompromised and has attained superbug notoriety since it is evident in hospitals and has inherent resistance to antibiotics.
Details
Type/Funding
  Identifying new drugs to combat the virulence mechanisms underlying multidrug-resistant typhoid.
University of Sheffield Department of Biomedical Science
  Dr D Humphreys
Applications accepted all year round
Multidrug-resistant typhoid. --------------------------------------------. The world is facing an epidemic of multidrug-resistant (MDR) typhoid fever.
Details
Type/Funding
  4 Year Wellcome Trust PhD Programme: Decoding virulence mechanisms in trypanosomes
University of Dundee School of Life Sciences
  Prof D Horn
Application Deadline: 8 April 2019
The African trypanosome, Trypanosoma brucei, is transmitted among mammalian hosts by tsetse flies. These unicellular parasites cause sleeping sickness or Human African Trypanosomiasis, typically fatal if left untreated, and the livestock disease known as nagana.
Details
Type/Funding
  Discovery of novel virulence factors from intracellular bacterial pathogens
University of Nottingham School of Life Sciences
  Dr A Huett
Applications accepted all year round
Secreted bacterial effector proteins allow bacterial pathogens to manipulate, subvert and invade host cells to establish and maintain an intracellular niche.
Details
Type/Funding
  Elucidating the mechanisms of phospholipid transport in Gram-negative bacteria
University of Birmingham School of Biosciences
  Research Group: BBSRC MIBTP
  Dr T Knowles
Applications accepted all year round
This project focuses on characterising the fundamental process of outer membrane lipid transport in Gram-negative bacteria, a largely unknown process which is only now being revealed.
Details
Type/Funding
  Serine/threonine protein kinase mediated regulation of protein secretion in mycobacteria
University of Leicester Department of Infection Immunity & Inflammation
  Dr G Mukamolova, Dr H O'Hare
Application Deadline: 5 May 2019
Tuberculosis remains a major global threat as it affects humans and production animals. Mycobacterium tuberculosis and Mycobacterium bovis, the causative agents of tuberculosis in human and animals, are highly successful pathogens which secrete multiple virulence factors.
Details
Type/Funding
  Characterisation of bacterial effectors delivered by the type VI secretion system
University of Sheffield Infection, Immunity and Cardiovascular Disease
  Dr M Thomas
Applications accepted all year round
Many bacterial virulence determinants are secreted proteins referred to as ’effectors’ that benefit the pathogen by allowing it to subvert, damage or kill the host.
Details
Type/Funding
  Molecular characterisation of novel pathways for cell envelope protein localisation in mycolic acid-producing actinomycetes (ref: SF18/APP/Sutcliffe)
Northumbria University Faculty of Health and Life Sciences
  Prof I Sutcliffe
Applications accepted all year round
Mycolic acid-producing actinomycetes are of vital economic and medical importance. They include pathogenic species including Corynebacterium diphtheriae, Mycobacterium tuberculosis and Rhodococcus equi as well as industrially important organisms.
Details
Type/Funding
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