or
Continue with FacebookLooking to list your PhD opportunities? Log in here.
virulence PhD Projects, Programmes & Scholarships
We have 57 virulence PhD Projects, Programmes & Scholarships
The sweet side of ‘evil twin’ sugars: using chemical glycobiology tools to explore the role bacterial sialic acids play in host immune evasion by pathogens
Sugars, or glycans as they are more commonly known, are the most abundant biomolecules on earth and play essential roles in a myriad of biological processes including energy storage, cell-cell recognition and the immunological response. Read more
Making sense of antigenic variation in trypanosomes: a nuclear factory with a switching problem…
Background. Many pathogens can undergo antigenic variation, one of the most sophisticated virulence mechanisms in infection biology. Read more
Predicting pathogen evolution: using experimental evolution to understand the impact of phage therapy on Clostridioides difficile
Antimicrobial resistance is one of the greatest challenges facing humanity today. We desperately need new therapeutic options and phage therapy - using viruses that kill bacteria - is widely seen as one such approach. Read more
Genomic insights into the transmission pathways of foodborne pathogens in fish from aquaculture to consumer in Thailand
The OneZoo CDT offers an unprecedented level of diversity and transdisciplinarity, with award-winning educators and experts in zoonotic diseases and environmental sciences from Cardiff University, Aberystwyth University, Queen’s University Belfast, and the London School of Hygiene and Tropical Medicine. Read more
Environmental function and biotechnological potential of proteases from extremely halophilic archaea
This project explores both the fundamental biological roles and biotechnological potential of proteases produced by extremely halophilic archaea. Read more
BBSRC NWD: Defining new strategies to treat AMR in Pseudomonas aeruginosa
Background. Pseudomonas aeruginosa (Pa) is a Gram-negative bacterium and an opportunistic pathogen that causes a wide range of infections, particularly in immunocompromised individuals and patients with chronic illnesses. Read more
Improved methodology for the detection and pathogenesis of acute oak decline
Studentship Details. Acute Oak Decline (AOD) is a complex tree decline disease threatening the native oak species in the UK. Symptoms of AOD include stem bleeds and inner bark tissue necrosis, which can cause death of mature oaks within just three to five years of symptom onset. Read more
Last chance to apply
EASTBIO: Targeting fungal E3 ligases with small-molecule ligands for degrader development
The increase in global trade of agricultural product coupled with climate change have driven the emergence of new pathogen species and genotypes. Read more
Last chance to apply
EASTBIO: Investigating mode of action and cellular impact of anti-bacterial effector toxins
Many species of bacteria use a contractile nanomachine called the Type VI secretion system (T6SS) to deliver a wide range of toxic proteins, known as ‘effectors’, directly into neighbouring cells. Read more
Last chance to apply
EASTBIO: Exploring the role of extracellular vesicles in insect pest saliva
Sap-feeding insect pests cause significant economical damage to crops globally. While probing and feeding these insects secrete saliva inside their hosts which contains a wide range of molecules, including proteins, RNA, and metabolites. Read more
Last chance to apply
Unravelling the Regulatory Mechanisms of Effector-Triggered Immunity for Durable Plant Resistance
Plant immunity heavily relies on R proteins capable of recognising pathogens and activating immunity. Yet this resistance often breaks under field conditions. Read more
Last chance to apply
Understanding the role of the flagellum in Trypanosoma cruzi intracellular parasitism
Parasitism, in which one species benefits at the expense of another species by living in or on it, is one of the most common modes of life. Read more
Last chance to apply
Functional and structural characterisation of glycosyltransferases involved in protein mannosylation
Glycosylation is one the most abundant post-translational modifications and an evolutionary indicator. indeed the increasing complexity of host-pathogen and organism-environment interactions, amongst others, is reflected in the newly-reported ability of prokaryotes (e.g. Read more
Last chance to apply
Type VII ABC transporters: New biology in the bacterial cell envelope
Type VII ABC transporters are ATP-powered membrane proteins that perform essential functions in the bacterial cell envelope. Read more