Defining the function of new causal atherosclerosis genes from CAD GWAS loci using in vitro and in vivo models Despite significant advancements in its treatment coronary artery disease is the leading cause of death in both the UK and world wide, accounting for over 66,000 deaths in the UK each year. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
We are looking for a highly motivated student to work with us on an exciting project to develop in fluorescent tools optimised for in vivo imaging and investigate glucose levels in lungs. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Project Description. The microbiomes found in animals are critical for the wellbeing of their hosts. These microbial communities ensure proper function of several biological processes, ranging from metabolism to immune system development and pathogen resistance. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This research project has funding attached. It is only available to UK citizens or those who have been resident in the UK for a period of 3 years or more. Some projects, which are funded by charities or by the universities themselves may have more stringent restrictions.
This project looks to develop a platform technology that utilises external stimuli, such as light for the triggered polymer un-coating of viral vectors for in-vivo targeted delivery. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.
Inflammation, driven by leucocytes, adversely affects organ function in diseases such as myocarditis, myocardial infarction, acute lung injury, sepsis and pancreatitis,. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Rationale. Vascular smooth muscle cell (VSMC) proliferation leads to intimal thickening, which causes reoccurrence of symptoms (restenosis) in 30-50% of coronary artery disease patients receiving saphenous vein grafts and individual receiving stent implantation. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Brief Rationale. The long saphenous vein (LSV) is the most commonly used conduit in cardiac surgery to treat patients with coronary artery disease; however, its use is complicated by high failure rates due to the development of vascular inflammation, intimal hyperplasia (IH) and accelerated atherosclerosis. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Phosphoinositide lipids (PIPs) play critical roles in development and the homeostasis of adult tissues and their dysfunction has been linked to major human diseases such as cancer, diabetes, myopathies and neuropathies. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
A critical role for phagocytic cells such as macrophages is the engulfment and subsequent degradation of dying cells and debris. Failure to clear targets such as apoptotic cells can lead to damaging autoimmune conditions and immune cell dysfunction (Morioka et al., 2019; Roddie et al., 2019). Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Application deadline. 3rd March. Interviews to be held. 31 March 2021. The first semester of this project will be based at the University of Manchester and the remaining duration will be based at the University Sheffield as this CDT is a partnership between the two universities. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Application deadline. 3rd March. Interviews to be held. 31 March 2021. The first semester of this project will be based at the University of Manchester and the remaining duration will be based at the University Sheffield as this CDT is a partnership between the two universities. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Retinal degeneration is the leading cause of blindness in developed countries. The new exciting biological approach of optogenetic therapy in which ectopic expression of photosensitive proteins (photopigments) is used to restore photosensitivity, offers a potential breakthrough for treating these conditions. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Sprouting of new capillaries from pre-existing vessels (angiogenesis) promotes the formation of almost all blood vessels during development, growth and tissue regeneration. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.