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We have 226 vivo PhD Projects, Programmes & Scholarships

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vivo PhD Projects, Programmes & Scholarships

We have 226 vivo PhD Projects, Programmes & Scholarships

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Investigating the mechanisms for cardiac fibrosis development and reversal

University of Birmingham Institute of Cardiovascular Sciences
Research interests/description of main research theme. Fibrosis is a hard to treat condition of major socioeconomic importance, with ~45% of all deaths in the developed world being attributed to some type of chronic fibro-proliferative disease and is exemplified by heart disease. Read more
 Supervisors: Dr D Pavlovic, Dr C O'Shea
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences
The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more
 Supervisor: Dr B Poulet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics
Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more
 Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health
The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more
 Supervisors: Dr G Mavria, Dr S Bell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences
Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more
 Supervisors: Dr D Ramji, Dr T Hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Feeding microbes to protect the brain: does the gut microbiota mediate the risk-reducing effects of a healthy diet on Alzheimer’s disease?

Queen Mary University of London Institute of Dentistry
Background. Ways of reducing the risk of developing Alzheimer’s disease (AD) and other dementias are critically needed, given the almost total lack of truly effective therapeutic options, even despite newer anti-amyloid drugs1. Read more
 Supervisors: Dr S McArthur, Dr E Hagi-Pavli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health
Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more
 Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Inhibiting cell metabolism to enhance tumour cell death

University of Leeds Faculty of Medicine and Health
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
 Supervisors: Dr S Papa, Dr R Tooze
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Untangling how Shelterin safeguards telomere structure and stability - one molecule at a time

University of Sheffield School of Biosciences
Background. Telomeres solve two problems with linear chromosomes. the end-replication problem, DNA loss from the end of chromosomes every replication cycle; and the end-protection problem, protection of the chromosome ends to prevent chromosome fusions. Read more
 Supervisors: Dr M Newton, Dr A Pyne
 3 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

The University of Manchester Faculty of Biology, Medicine and Health
Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more
 Supervisors: Dr S Nagarajan, Dr HH Harrison, Prof R Clarke, Dr I Iqbal
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health
Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more
 Supervisors: Prof D Brough, Dr K Couper
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Fully funded PhD studentship: Transforming respiratory care at the bedside using machine learning assisted on-chip vibrational spectroscopy

University of Southampton Faculty of Engineering and Physical Sciences
Supervisory Team. Prof. Senthil Murugan Ganapathy. Project description. Acute respiratory distress syndrome (ARDS), a widespread respiratory condition affecting all ages, causes respiratory failure due to inflamed, fluid-filled lungs hindering gas exchange. Read more
 Supervisor: Prof S Ganapathy
 Year round applications  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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Self-funded PhD- Interplay between environmental toxins and cancer predisposition

University of Bristol School of Cellular and Molecular Medicine
Cancer arises in part from intrinsic molecular and cellular alterations. For instance, loss of major DNA damage response genes such as BRCA1/2 has long been known to predispose individuals to multiple cancer types. Read more
 Supervisor: Dr S Koh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Innovative Biological Scaffolds for Regenerative Replacement of Dysfunctional Heart Valves

University of Leeds Faculty of Biological Sciences
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisor: Dr H.E. Berry
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Vascularising human mini-brains in a dish

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Blood vessels play a pivotal role in brain development and function. They promote tissue growth and survival by supplying nutrients and oxygen to surrounding tissues, signals to progenitor populations, as well as guiding neuronal migration. Read more
 Supervisors: Dr PA Alexandre, Prof D Long
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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