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x-ray crystallography PhD Projects, Programs & Scholarships

We have 52 x-ray crystallography PhD Projects, Programs & Scholarships

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  Conformational dependence of glycan geometry in protein glycosylation: applications for macromolecular refinement in atomic structure determination by X-ray crystallography and electron cryo-microscopy
  Dr J Agirre, Dr K D Cowtan
Applications accepted all year round
Proteins are composed of 20 individual building blocks, the L-amino acids, linked together by a largely inflexible amide bond.
  Structure, dynamics and interactions of subunits of RNA polymerase of Gram-positive bacteria
  Prof L Zidek, Dr P Kaderavek
Application Deadline: 15 March 2019
Certain RNA polymerase subunits (including sigma factors) are specific for Gram-positive bacteria. Such subunits are critical determinants of the enzyme specificity for DNA promoter sequence.
  Structural Studies on the Killing of Bacterial Prey by the Predatory Bacterium Bdellovibrio bacteriovorus
  Dr A Lovering
Applications accepted all year round
Bdellovibrio bacteriovorus is a small predatory bacterium able to invade and kill many different Gram-negative bacterial prey (including human, animal and crop pathogens; e.g.
  Structure and Function Studies on Proteins from Predatory Bacteria
  Dr A Lovering
Applications accepted all year round
Bdellovibrio bacteriovorus is a small predatory bacterium able to invade and kill many different Gram-negative bacterial prey (including human, animal and crop pathogens; e.g.
  Understanding a molecular architecture of the centriole / basal body
  Dr T Ochi
Application Deadline: 31 January 2019
The aim of this PhD project is to determine the molecular assembly mechanism of a structure of the centriole / basal body by a combined approach of structure biology (cryo-EM and X-ray crystallography) and biochemistry in order to understand underlying mechanisms that cause ciliopathies and cancer.
  Bacteriophages of Gram positive bacteria: gateways to infection control
  Dr G Xia, Prof J P Derrick
Applications accepted all year round
The rise in antibiotic resistance has prompted a renewed interest in bacteriophage research. A study of the molecular basis for recognition of the bacterial host has applications in detection, vaccine design and control of bacterial infections.
  Structure and function of key ABC Transporters in health and disease
  Prof L Carpenter, Dr H de Wet
Application Deadline: 25 January 2019
Human ABC transporters are a family 52 integral membrane proteins that transport diverse molecules across cell membranes. Mutations in ABC transporters causes a range of diseases, including diabetes (ABCC8 and ABCC9), cystic fibrosis (ABCC7, CFTR) and blindness (ABCA4).
  3-YEAR PhD Studentship: Molecular mechanisms in brain development
  Dr E Seiradake
Application Deadline: 15 February 2019
Background. ’Cell guidance receptors’ are specialised proteins that are found at the surfaces of cells. They direct the formation of complex tissues such as the neural and vascular networks.
  DNA Damage and Repair: Studying DNA damage and repair to understand the causes of cancer and improve its treatment
  Prof P McHugh, Prof J Rehwinkel, Prof A Harris
Application Deadline: 26 July 2019
Our DNA is constantly under threat from damaging agents. If unrepaired this DNA damage can lead to errors during genome duplication, including the mutations that can lead to cancer and other human diseases.
  Engineering Enzymes for Industrial Biotechnology
  Prof G J Grogan
Applications accepted all year round
Our research group is interested in the identification, characterization and application of enzymes of interest to biotechnology.
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