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structural biology PhD Projects, Programs & Scholarships

We have 208 structural biology PhD Projects, Programs & Scholarships

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  Control and inhibition of virus replication
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A.K Tuplin
Applications accepted all year round

Funding Type

PhD Type


The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specificaly Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.
  PhD in Chemical Biology -- Neuropeptide Research -- University of Vienna
  Prof M Muttenthaler
Applications accepted all year round

Funding Type

PhD Type

Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Structural and functional studies of outer membrane assembly in Gram-negative bacteria and mitochondria - DongMED_Oct2020
  Prof C Dong, Dr P Crichton
Application Deadline: 17 April 2020

Funding Type

PhD Type

The outer membrane plays essential roles in Gram-negative bacteria and mitochondria. Dysfunction of outer membrane proteins occur in several human diseases, such as diabetes, Parkinson and other neurodegenerative disease.
  Dissecting mechanisms of mRNA translational control by specialised ribosomes
  Research Group: BBSRC White Rose DTP
  Dr J Aspden, Dr J Fontana
Application Deadline: 6 April 2020

Funding Type

PhD Type

The average cell contains ~10 million ribosomes, comprised of ~80 ribosomal proteins and 4 rRNAs. Until recently it was thought that all ribosomes were the same.
  Fostering development of ‘smart’, responsive therapeutics against cancer-related microRNAs.
  Dr E Bichenkova, Prof D Clarke, Dr H Aojula
Applications accepted all year round

Funding Type

PhD Type

Short functional non-coding microRNAs are implicated in many types of cancer, and thus can be used as biological targets for development of more selective and powerful anticancer therapies.
  Mitochondrial protein folding and diseases
  Prof L-Y Lian, Dr D Criddle
Applications accepted all year round

Funding Type

PhD Type

Many diseases, including cancer and neurological disease, stem from mitochondrial dysfunctions often triggered by sudden elevation of agents such as calcium and reactive oxygen species.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  Development of chemical biology tools to study mammalian O-mannosylation pathways
  Dr L Willems, Prof G Davies
Applications accepted all year round

Funding Type

PhD Type

The field of chemical biology aims to design and synthesize chemical tools (such as inhibitors, substrate mimics, or enzyme probes) to answer fundamental questions in biology.
  Simultaneous gene transcription and translation in bacteria
  Dr Gabriel Demo
Application Deadline: 19 April 2020

Funding Type

PhD Type

OBJECTIVES. The research aims to unravel the fundamental mechanism of the transcription-translation coupling in bacteria.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round

Funding Type

PhD Type

In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
  PhD Student - Functional Analysis of UHRF1 (f/m/d)
  Dr T Bartke
Applications accepted all year round

Funding Type

PhD Type

As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases.
  Combining Synthetic Biology and Modelling to Understand and Predict Evolution
  Dr M Lagator, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Mutations, and their effects on organismal fitness, lie at the heart of understanding and predicting evolution. Because of its central role in determining evolutionary outcomes, much experimental and theoretical effort has been put into describing the fitness effects of mutations.
  MSc by Research Programme: Bringing proteins together with small molecules
  Prof A Ciulli
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  In silico discovery of the degrons and the degron-mediated recruitment modules of the human Ubiquitin E3 Ligase system
  Dr N Davey
Application Deadline: 1 May 2020

Funding Type

PhD Type

For details on how to apply using our online recruitment system please see http://icr.ac.uk/phds.
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