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We have 13 microglia PhD Projects, Programmes & Scholarships

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microglia PhD Projects, Programmes & Scholarships

We have 13 microglia PhD Projects, Programmes & Scholarships

MSc by Research: Nutrient-dependent regulation of microglia function and immune responses

Microglia are constantly sensing the brain environment for metabolic changes, damage and pathogenic invasion. Microglia are highly metabolically active, with activation in response to inflammatory stimulation increasing glycolytic demand. Read more

The role of GLUT transporters in microglial metabolism, investigating functionality, regulation and drug targetable properties.

Modifying the brain’s metabolism as an intervention or for the treatment of Alzheimer’s disease represents a novel strategy for targeting what is recognised as a multifactorial condition which lacks effective therapeutic options.   . Read more

Exploring the role of tryptophan metabolism in schizophrenia pathogenesis

L-kynurenine (KYN) and kynurenic acid (KYNA) are metabolites of the kynurenine pathway (KP) of tryptophan degradation and have been found to be increased in the brains of patients with schizophrenia. Read more

Metabolic modulation of microglial homeostasis and immune response

Microglia are a specialised immune cell found in the central nervous system. They are responsible for maintaining brain homeostasis and play an important role in the early onset and development of neuroinflammatory disorders such as Alzheimer’s disease. Read more

Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more

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