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We have 32 fibrosis PhD Projects, Programmes & Scholarships

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fibrosis PhD Projects, Programmes & Scholarships

We have 32 fibrosis PhD Projects, Programmes & Scholarships

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Investigating the mechanisms for cardiac fibrosis development and reversal

University of Birmingham Institute of Cardiovascular Sciences
Research interests/description of main research theme. Fibrosis is a hard to treat condition of major socioeconomic importance, with ~45% of all deaths in the developed world being attributed to some type of chronic fibro-proliferative disease and is exemplified by heart disease. Read more
 Supervisors: Dr D Pavlovic, Dr C O'Shea
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unravelling the biophysical mechanisms that regulate liver fibrosis

Aston University College of Health and Life Sciences
Applications are invited for a Postgraduate studentship, supported by the Engineering and Physical Sciences Research Council Doctoral Training Programme, to be undertaken within the College of Health and Life Sciences at Aston University. Read more
 Supervisor: Dr E Shepherd
 16 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences
Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function.  At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more
 Supervisors: Prof S Arthur, Dr H McSorley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding the link between fibrosis, inflammation, and breast cancer initiation

University of Leicester Molecular and Cell Biology
Understanding the fundamental molecular events that result in tumour initiation is critical to the prevention and treatment of human cancers. Read more
 Supervisor: Dr C Switzer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the Therapeutic Potential of Cannabidiol (CBD) in Cardiac Fibrosis

University of Reading School of Pharmacy
Cardiac fibrosis is a condition that is characterized by the abnormal accumulation of fibrous tissue within the heart muscle and poses a significant threat to cardiovascular health. Read more
 Supervisors: Dr G Cottrell, Prof D Widera
 31 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

University of Dundee School of Medicine
Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more
 Supervisor: Dr M Mclean
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Functional effects of variable number tandem repeat expansions in idiopathic pulmonary fibrosis

University of Leicester Department of Genetics and Genome Biology
  Research Group: Human & Medical Genetics
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by the formation of scar tissue in the lungs. Read more
 Supervisor: Prof E Hollox
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

University of Leeds Faculty of Medicine and Health
Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more
 Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Deciphering the cell death-dependent fibrotic niche following lung injury

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: Centre for Inflammation Research
Background. Lung disease causes 1 in 5 deaths globally with limited treatment advances for many acute and chronic respiratory conditions. Read more
 Supervisors: Dr C Lucas, Dr DD Dorward, Dr P Ramachandran
 13 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Stress hormone metabolism – a novel anti-fibrotic therapeutic pathway for chronic wounds (Ref SHLS24121)

Glasgow Caledonian University School of Health and Life Sciences
We have an exciting PhD opportunity within the Molecular Mechanisms of Long-term Conditions research group at Glasgow Caledonian University (https://www.gcu.ac.uk/aboutgcu/academicschools/hls/research/researchgroups/molecularmechanismsoflongtermconditions) to join the laboratory of Dr Catherine Wright with a supervisory team based in GCU and the University of Leeds. Read more
 Supervisors: Dr C Wright, Dr S Patterson, Dr B Alcacer-Pitarch
 30 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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MScR: Cystic fibrosis: restoring ion transport with small molecules

University of Bristol School of Physiology, Pharmacology & Neuroscience
Cystic fibrosis (CF) is caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR), a unique ATP-binding cassette transporter that functions as an ATP-gated anion channel, playing a pivotal role in salt and water movement across epithelial tissues (1). Read more
 Supervisor: Prof D N Sheppard
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy
Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy
Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

Queen’s University Belfast School of Pharmacy
The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more
 Supervisor: Prof M Tunney
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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