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monoclonal antibodies PhD Projects, Programs & Scholarships

We have 12 monoclonal antibodies PhD Projects, Programs & Scholarships

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  (BBSRC DTP) Development of anti-cancer agents and biomarkers that target intrinsically disordered regions of transcription factors and protein kinases
  Prof J Waltho, Dr A Almond
Application Deadline: 31 January 2020

Funding Type

PhD Type

The controlled manipulation of transcription factors, protein kinases and protein phosphatases is central to improving our understanding of cellular processes and, importantly, in the development of next-generation therapeutics for a variety of cancers.
  (BBSRC DTP CASE) Understanding and predicting the immunogenicity of therapeutic protein products
  Prof J P Derrick, Dr R Dearman
Application Deadline: 31 January 2020

Funding Type

PhD Type

Biopharmaceuticals, or therapeutic protein products (TPPs) have been in widespread clinical use for several decades. They comprise a wide range of pharmaceutical products, from vaccines to hormones, cytokines and monoclonal antibodies.
  Reprogramming the innate immune system to treat malignancy: targeting ovarian cancer
  Prof M A Vickers, Prof I Stansfield, Prof H M Wilson
Application Deadline: 17 February 2020

Funding Type

PhD Type

Despite the major advances achieved in recent years by redirecting the adaptive immune system to recognise cancer cells (notably monoclonal antibodies, checkpoint inhibitors and chimaeric antigen receptor T cells), the therapeutic potential of innate immunity remains underexploited.
  Chemical biology tools for drug development
  Dr J Konvalinka, Dr P Sacha
Application Deadline: 23 February 2020

Funding Type

PhD Type

Laboratory of Jan Konvalinka looks for a PhD candidates to work on development of several novel chemical biology tools for drug design, target discovery and validation, compound screening and target protein visualization.
  Elucidation of novel therapy targets for B-cell malignancies
  Dr M Smida
Application Deadline: 20 February 2020

Funding Type

PhD Type

Therapy of B-cell lymphomas and B-cell chronic lymphocytic leukemia is based predominantly on CD20 monoclonal antibodies and/or on three approved targeted drugs.
  Optimisation and Preclinical Evaluation of Targeted Nanoformulations of Anti‐TNF‐α Therapeutics for the Treatment of Inflammatory Bowel Disease (IBD)
  Dr Z Ramtoola, Dr B Kirby
Applications accepted all year round

Funding Type

PhD Type

Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition that affects the gastrointestinal tract (GIT) of the patient and comprises of Crohn’s disease (CD) and ulcerative colitis (UC).
  (A*STAR) Protein solubility in biology and biotechnology
  Dr J Warwicker, Dr R Curtis
Application Deadline: 31 January 2020

Funding Type

PhD Type

Protein aggregation is an issue in biology and biotechnology. A wealth of studies have focussed on proteinopathies and neurodegenerative diseases in particular.
  (BBSRC DTP) Developing a whipworm vaccine composed of virus-like particles expressing Trichuris T cell epitopes
  Prof K Else, Prof J P Derrick
Application Deadline: 31 January 2020

Funding Type

PhD Type

Vaccination is one of the greatest advances in global health; however most successful vaccines have been made empirically. We still have little insight into how many vaccines work and the mechanisms by which they trigger protective immune responses.
  Developing next-generation inducible gene expression systems for biopharmaceutical manufacturing
  Dr A Brown
Application Deadline: 29 January 2020

Funding Type

PhD Type

Biopharmaceuticals offer therapeutic promise for treating many currently incurable conditions, including cancer, neurological disorders and cardiovascular diseases.
  Tetraspanin structure and function
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  Tetraspanin structure and function
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  Development of small molecule inhibitors of FcεRI
  Prof D Cox, Dr M Adamo
Applications accepted all year round

Funding Type

PhD Type

Allergic diseases are one of the most common diseases in the Western world. A report from the American academy of allergy, asthma and immunology indicated that between 40-50% of children are sensitized to at least one allergen.
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