pharmaceutical engineering PhD Projects, Programmes & Scholarships

We have 98 pharmaceutical engineering PhD Projects, Programmes & Scholarships

New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more

Supervisors: Dr R Wheelhouse, Prof A Paradkar, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more

Supervisors: Dr J Muller, Prof R Falconer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Supervisor: Dr Muhammad Wahajuddin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Supervisors: Dr M Hussain, Dr C Willis, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid

Year round applications PhD Research Project Self-Funded PhD Students Only

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Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Contraction in the heart is well known to be dependent on a transient rise in intracellular calcium concentration. Read more

Supervisors: Dr M Hussain, Dr J Muller, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of vitamin D3 in treating skin cancer and preventing drug resistance

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more

Supervisors: Dr M Sutherland, Dr H Sheldrake, Dr S Kauser

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Neuronal control of appetite: investigating the role of the extracellular matrix in controlling neuronal activity in the hypothalamus

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Appetite regulation is complex, and its dysregulation has serious implications for health, being observed in multiple conditions e.g., obesity, anorexia, and type 2 diabetes. Read more

Supervisors: Dr SM Dickens, Dr G Helfer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Microbiology of Hip Arthroplasty Cements

University of Bradford Faculty of Life Sciences

Research Group: Centre for Skin Sciences

Replacement hip and knee arthroplasties are common surgeries, with 31,000 hip and 90,000 knee replacements performed in England in 2020-21. Read more

Supervisors: Dr A Scimone, Dr T Swift

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of the extracellular matrix as a regulator of Parkinson’s progression

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Parkinson’s is the 2nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is set to rise by 50% over the next 50 years due to ageing populations. Read more

Supervisor: Dr SM Dickens

Year round applications PhD Research Project Self-Funded PhD Students Only

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Spatially resolved spectroscopy for pharmaceutical manufacturing process

University of Strathclyde Department of Chemical and Process Engineering

Tablet is a complex pharmaceutical product in oral dosage form which contains blends of active pharmaceutical ingredients (APIs) and excipients. Read more

Supervisor: Dr Y Chen

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

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Understanding how formulation parameters influence the performance of novel capsule formulations

Cardiff University Cardiff School of Pharmacy and Pharmaceutical Sciences

Two-piece capsules are used in dry powder inhalers (DPIs) as a single-dose container for powdered pharmaceutical formulations. These formulations contain active pharmaceutical ingredients to treat pulmonary conditions, such as asthma and chronic obstructive pulmonary disease. Read more

Supervisor: Dr S Coulman

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 98 pharmaceutical engineering PhD Projects, Programmes & Scholarships

pharmaceutical engineering PhD Projects, Programmes & Scholarships

We have 98 pharmaceutical engineering PhD Projects, Programmes & Scholarships

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