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We have 170 php PhD Projects, Programmes & Scholarships

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php PhD Projects, Programmes & Scholarships

We have 170 php PhD Projects, Programmes & Scholarships

Peptide-based nanoparticles for brain targeted gene delivery.

Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more

Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more

Self-regulating, self-cleaning biomaterials

A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required. Read more

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Self-Navigating Nanocarriers for Intracellular Protein Delivery

Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more

Development of multifunctional biomaterials for urinary catheters to eradicate catheter-associated urinary tract infections

Catheter-associated urinary tract infections (CAUTIs) are among the most common hospital-acquired infections worldwide threatening over 150 million people annually, imposing substantial burdens on the health system. Read more

MICROFLUIDIC TECHNOLOGIES FOR THE PRODUCTION OF NANOMEDICINES

Progress in drug design has led to the development of new molecules. However, the limited ability to selectively deliver these molecules at well-defined dosing regimens remains a significant challenge. Read more

Self-Navigating Nanocarriers for Intracellular Protein Delivery

Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more

Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis

Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more

Adaptation to environmental change in animals: ecology, evolution and genomics.

How are animals able to live in different environments, with different temperatures, energetic demands, diet, predators, parasites or pH? Thanks to advances in gene sequencing technology, we are in a remarkable period of discovery about the genomic basis of adaptation and how this depends on the intricacies of ecology and environment. Read more

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