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proteomic PhD Projects, Programs & Scholarships

We have 37 proteomic PhD Projects, Programs & Scholarships

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  A proteomic study of serum from children with neurofibromatosis type 1 autism
  Prof J Green, Dr S Garg, Dr R Unwin
Applications accepted all year round

Funding Type

PhD Type

Proteomic approaches using mass spectrometric analysis have proved a valuable tool in understanding the molecular pathogenesis of complex disorders such as schizophrenia and ASD.
  Activity based proteomic probes for profiling CYP2W1 in cancer tissues
  Research Group: Institute of Cancer Therapeutics
  Dr C Sutton, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Cytochromes P450 (CYPs) are a superfamily of mixed function oxidases of which CYP1-4 subfamily members are unique in their ability to oxidise drugs.
  Proteomic Markers of Chronic Renal Scarring
  Dr P Watson
Applications accepted all year round

Funding Type

PhD Type

All types of chronic kidney disease (CKD) progress to end stage renal failure through a common pathway of fibrosis and scarring. Subsequently 2 million patients worldwide require renal replacement therapy (RRT).
  Elucidation of the role of newly discovered post-translational modification of proteins involved in hypoxia signalling using proteomic analysis and live cell imaging
  Dr V See, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

The hypoxia signalling pathway is required for the adaptation of cells to a low oxygen environment, which cells can experience in various physiological and pathological circumstances related to high altitude, development, wound healing and cancer.
  (MRC CASE) Analysis of Advanced Motion Kinetics and Kinematics, Correlated with Proteomic Approach to Biological Assessment of the Joint to Develop Optimised Personalised Knee Arthroplasty Surgery and Rehabilitation
  Ms L Biant, Prof T Freemont, Dr C Milner
Application Deadline: 14 June 2019

Funding Type

PhD Type

This project runs at the interface of biomedical engineering, cell biology and clinical orthopaedic surgery. It is a directly translatable project that allows the student to develop skills applicable to a variety of disciplines and also experience with patient interaction.
  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  Proteomic analyses of adhesion signalling in cancer
  Prof M J Humphries, Dr C Jorgensen
Applications accepted all year round

Funding Type

PhD Type

Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation, and they underpin a metazoan (multicellular) existence.
  Proteomic approach to understand mitochondrial quality control under normal and stress conditions
  Dr H Lu, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Defects in protein quality control lead to the accumulation of misfolded and damaged proteins, which play an important role in many diseases (e.g.
  The generation of RBCs in vitro from stem cell sources and the molecular regulation of erythropoiesis.
  Dr J Frayne
Applications accepted all year round

Funding Type

PhD Type

Development of systems for the generation of red blood cells (RBCs) from stem cells sources (adult peripheral blood, cord blood and pluripotent stem cells)…
  Impact of alternative mRNA splicing on the human proteome
  Dr V Wickramasinghe, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

Alternative splicing of RNA transcripts has emerged as a key mechanism for enabling biological complexity within the human genome.
  Elucidating the interplay between mitochondrial dynamics, organelle contact sites and metabolic (re)programming (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Dr J Prudent
Application Deadline: 30 June 2019

Funding Type

PhD Type

Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell.
  Molecular mechanisms of neuronal ageing in bladder and bowel neurons (ref: SF18/APP/Ranson)
  Dr R Ranson
Applications accepted all year round

Funding Type

PhD Type

Ageing results in a progressive loss of physiological function resulting in a reduced quality of life in the elderly. One of the more prevalent conditions associated with ageing is incontinence-both faecal and urinary.
  Novel drug target validation for treating Diabetes Mellitus (ref: SF18/APP/Soundararajan)
  Dr M Soundararajan
Applications accepted all year round

Funding Type

PhD Type

The important cellular entities responsible for fighting against infections in our body are the T cells. T cells are however also shown to play a central role in the development of autoimmune diseases (AIDs) as “T cell activation hijacking” is the major autoimmune reaction causing mechanism observed in several AIDs.
  The role of isothiocyanates-derived from natural sources in uveal melanoma chemoprevention (ref: SF18/APP/McDermott)
  Prof A McDermott, Prof M Panagiotidis, Dr G Koutsidis
Applications accepted all year round

Funding Type

PhD Type

Uveal melanoma is the most frequent primary intraocular tumor, in Caucasian adults, and one that is very difficult to treat once it becomes metastatic.
  Functional analysis of fungal effector proteins in the barley/wheat powdery mildew plant-pathogen interactions.
  Dr L Bindschedler, Prof A Devoto
Applications accepted all year round

Funding Type

PhD Type

Pathogens secrete small proteins called effectors or virulence factors which are important for the successful invasion of the host.
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