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structural biology PhD Projects, Programs & Scholarships

We have 258 structural biology PhD Projects, Programs & Scholarships

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  Targeting DNA repair to overcome cancer therapy resistance
  Prof P McHugh, Prof T Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. DNA cross-linking drugs and radiotherapy (RT) are used to treat a range of tumours including many hard-to-treat cancers (e.g.
  Regulating biosynthesis of the pigments of life
  Dr A Hitchcock, Dr P Jackson, Prof C N Hunter
Application Deadline: 31 March 2020

Funding Type

PhD Type

Tetrapyrroles are often referred to as the pigments of life as they are required for a number of vital cellular processes, including respiration (haems), photosynthesis (chlorophylls), amino acid biosynthesis (vitamin B12), sulphur and nitrogen assimilation (sirohaem) and methanogenesis (cofactor F430).
  Protein engineering enzymes for Industry
  Prof K A Watson
Applications accepted all year round

Funding Type

PhD Type

We are interested in key features of protein sequence - structure - function relationship, and how this information can be translated to health.
  Harnessing Reactive Phosphorylating Agents for Peptide Bioconjugations
  Dr D Hodgson, Prof I Hickson, Prof M Noble
Application Deadline: 6 March 2020

Funding Type

PhD Type

Protein-protein interactions (PPIs) are central to signalling processes associated with many diseases. Disruption of PPI-mediated pathways offers new therapeutic targets, with great potential for selective, potent inhibition because they can mimic native protein structures.
  Harnessing Reactive Phosphorylating Agents for Peptide Bioconjugations - EPSRC Centre for Doctoral Training (CDT) in Molecular Sciences for Medicine (MoSMed)
  Dr D Hodgson
Application Deadline: 6 March 2020

Funding Type

PhD Type

Overview. Protein-protein interactions (PPIs) are central to signalling processes associated with many diseases. Disruption of PPI-mediated pathways offers new therapeutic targets, with great potential for selective, potent inhibition because they can mimic native protein structures.
  Computer Simulations of G protein-coupled Receptors
  Dr I Tikhonova
Applications accepted all year round

Funding Type

PhD Type

Many physiological processes are controlled through the activation of G protein-coupled receptors (GPCRs) by regulatory peptides, making peptide GPCRs particularly useful targets for major human diseases such as diabetes and CNS diseases.
  Molecular and genetic mechanisms of brain structural plasticity and neurodegeneration in the fruit-fly Drosophila.
  Dr A Hidalgo
Applications accepted all year round

Funding Type

PhD Type

The brain changes throughout life. brain plasticity enables the brain to adjust in response to experience, whereas during aging natural neurodegeneration takes over.
  Highly-diverse, synthetic gene libraries for antibody replacement technology
  Dr A Hine, Dr AJ Sutherland
Application Deadline: 28 February 2020

Funding Type

PhD Type

Applications are invited for a three year Postgraduate studentship funded by the School of Life and Health Sciences and the EU H2020 FET-OPEN programme, to be undertaken within the Biosciences Research Group at Aston University.
  Doctoral Candidate: Chemoenzymatic selective oxidation for the synthesis of rare sugars (ESR 12)
  Ms J Weber
Application Deadline: 1 March 2020

Funding Type

PhD Type

Doctoral Candidate. Chemoenzymatic selective oxidation for the synthesis of rare sugars (ESR 12). in Graz (AT) and Straubing (DE).
  Dissecting the tubulin diversity: understanding how tubulin isotypes regulate microtubule networks
  Dr J Ti
Applications accepted all year round

Funding Type

PhD Type

α/β-tubulin heterodimers form dynamic polymers, microtubules, that are central to cellular processes, such as cell division, cell migration, and organelle transportation.
  MRC DTP 4 Year PhD Programme: Structural and developmental mechanics in polarized membrane trafficking
  Dr D H Murray, Dr J Januschke
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Improving Photosynthetic Efficiency - Engineering and Evolution of Light-Harvesting Complexes via Synthetic Biology
  Dr D Canniffe
Applications accepted all year round

Funding Type

PhD Type

Photosynthesis is the ultimate source of food and energy for almost all forms of life. Using sunlight as the energy input, photosynthesis removes carbon dioxide from the atmosphere generating the oxygen and carbohydrate that support complex life.
  EPSRC CASE PhD studentship: Novel high-throughput approaches for the rapid analysis of target engagement by mass spectrometry (collaboration with Medicines Discovery Catapult)
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof F. Sobott, Dr J.R. Ault
Application Deadline: 28 February 2020

Funding Type

PhD Type

The ability to provide fast and efficient readouts for drug engagement with targets (proteins and oligonucleotides) is a key driving technology in the biopharma pipeline, e.g.
  Unravelling the mechanism of viral factory formation. An unexplored target for the development of novel antivirals (fully funded PhD).
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A Calabrese
Application Deadline: 6 March 2020

Funding Type

PhD Type

Viral replication factories (sites of viral replication/assembly) are formed when a number of important human and animal pathogens infect cells, including influenza, rabies, measles and rotavirus.
  Targeting hematological malignancies using fragment-based drug design
  Dr V Veverka
Application Deadline: 23 February 2020

Funding Type

PhD Type

The project will be focused on the knowledge-based design of active compounds targeting several proteins or protein-protein interactions, which are implicated in the development of hematological malignancies (acute lymphoblastic leukemia and mixed-lineage leukemia).
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