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structural biology PhD Projects, Programs & Scholarships

We have 241 structural biology PhD Projects, Programs & Scholarships

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  Novel applications of liquid MALDI MS for the analysis of large biomolecules
  Prof R K Cramer, Dr G Brown, Prof M Morris
Application Deadline: 1 March 2020

Funding Type

PhD Type

This PhD project will investigate novel applications of liquid MALDI MS in the areas of hydrogen/deuterium exchange for structural biology, native mass spectrometry, top-down biomolecule analyses and enzyme assay and kinetics measurements.
  The biophysics of phase separation in motor neurone disease
  Dr R Staniforth, Dr R Highley, Dr A Parnell
Application Deadline: 31 March 2020

Funding Type

PhD Type

The majority of neurodegenerative conditions are characterised by pathological inclusions of aggregated protein and motor neurone disease (MND) is no exception.
  The Biology of Parasitism in Parasitic Nematodes
  Prof M Viney
Applications accepted all year round

Funding Type

PhD Type

We work on the biology of parasitic nematode worms, particularly Strongyloides spp. The recent, detailed characterisation of the Strongyloides genome (Hunt et al.
  Molecular analysis of the dynamic sulfotyrosine proteome
  Prof C E Eyers, Prof P Eyers, Dr A R Jones
Applications accepted all year round

Funding Type

PhD Type

The survival of an organism depends upon the ability of different cell types to communicate with each other by assembling the correct complexes of proteins at the correct time in the correct place.
  Next-generation protein engineering: integration of ab-initio modelling, high-throughput screening and structural fingerprinting by mass spectrometry
  Prof F. Sobott, Dr E Paci, Dr A Calabrese
Applications accepted all year round

Funding Type

PhD Type

Recombinant proteins are playing an ever-increasing role as therapeutics and reagents. High-affinity binding candidates can be produced in a high-throughput manner through the process of selection and evolution from large libraries.
  Multi-omics investigations for enhanced understanding of NF-κB mediated drug resistance
  Prof R Goodacre, Prof N Perkins, Prof C E Eyers, Dr A R Jones
Application Deadline: 1 June 2020

Funding Type

PhD Type

We have an established system that can be used to investigate the role of NF-κB signalling in the cancer cell response to DNA replication stress and have generated cell lines which are resistant to treatment with a highly selective and specific CHK1 inhibitor (CCT244747).
  4-year Interdisciplinary PhD Programme ‘From Structures to Systems’ at the Institute for Structural and Molecular Biology at UCL and Birkbeck

Funding Type

PhD Type

Fully funded PhD studentships available for entry in Autumn 2020. In this exceptional programme students are exposed to a wide range of multidisciplinary training necessary to address essential problems in fundamental biology and biomedicine.
  4-year Interdisciplinary PhD Programme ‘From Structures to Systems’ at the Institute for Structural and Molecular Biology at UCL and Birkbeck

Funding Type

PhD Type

Fully funded PhD studentships available for entry in Autumn 2020. In this exceptional programme students are exposed to a wide range of multidisciplinary training necessary to address essential problems in fundamental biology and biomedicine.
  (Photo)Synthetic Biology - Engineering Biohybrid Photosystems For Enhanced Solar Energy Conversion in Devices
  Dr M R Jones
Applications accepted all year round

Funding Type

PhD Type

There is growing interest in the use of photosynthetic proteins in devices for solar energy conversion, biosensing, photosensing, photocatalysis, touch sensing, molecular electronics and biodegradable solar cells.
  A mechanistic understanding of allosteric regulation of neuronal sodium-activated potassium channels
  Research Group: BBSRC White Rose DTP
  Dr J D Lippiat, Dr S Muench, Dr A Kalli
Applications accepted all year round

Funding Type

PhD Type

The sodium-activated potassium channel KNa1.1 (KCNT1, Slack, Slo2.2) is found in neurons and couples sodium influx to excitability.
  Defining a novel assembly pathway in ssRNA viruses using X-ray footprinting.
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Project co-supervised by Prof. Peter Stockley at Leeds and Prof. Reidun Twarock at University of York, as part of the White Rose network "Structural and Mechanistic Biology at the RNA/Ligand Interface".
  Targeting mitochondrial dynamics to prevent Parkinson’s disease
  Prof A Sivaprasadarao, Dr R.S. Bon
Application Deadline: 1 June 2020

Funding Type

PhD Type

A common feature of Parkinson’s disease (PD) is the presence of alpha-synuclein protein aggregates in the brains of affected patients.
  Nanoinjection: a single molecule technique to study amyloid toxicity in neurons
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford, Dr P Actis
Applications accepted all year round

Funding Type

PhD Type

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.
  Characterising and repurposing cyanobacterial CO2-fixing organelles for metabolic engineering
  Prof LN Liu, Dr J Hartwell
Applications accepted all year round

Funding Type

PhD Type

Compartmentalisation represents an effective strategy used by cells to enhance their activities. By creating physical barriers and compartments, cells sequester the metabolic pathways from the cellular milieu to allow controls of metabolic flux and toxic diffusion.
  Development of metabolomics for understanding AMR in mixed infections
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

Without correct antibiotic stewardship we could be cast back to a pre-infective era where we have run out of antibiotics to treat life-threatening infections.
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