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We have 72 transcription PhD Projects, Programmes & Scholarships

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transcription PhD Projects, Programmes & Scholarships

We have 72 transcription PhD Projects, Programmes & Scholarships

Gene regulation in cancer metastasis

A PhD project studying gene regulation in cancer metastasis is available in the laboratory of Dr. Fiona Wardle (https://www.kcl.ac.uk/research/wardle-group) in the Randall Centre for Cell and Molecular Biophysics, King’s College London. Read more

Exploring the role of interferon stimulated genes (ISGs) in stem cells of serous ovarian cancer

  Research Group: Institute of Cancer Therapeutics
Epithelial ovarian cancer (EOC) is the leading cause of mortality in women due to gynaecological cancers. High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of patients with EOC. Read more

Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

The role of GLUT transporters in microglial metabolism, investigating functionality, regulation and drug targetable properties.

Modifying the brain’s metabolism as an intervention or for the treatment of Alzheimer’s disease represents a novel strategy for targeting what is recognised as a multifactorial condition which lacks effective therapeutic options.   . Read more

MSc by Research: Genetic interactions and novel genes that regulate lignin biosynthesis and straw quality in barley

Lignin is a major component of plant cell walls, and has a significant influence on the digestibility and uses of plant biomass. The lignin biosynthesis pathway has been one of the most intensively studied. Read more

Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder

Tousled-like kinase 2 (TLK2) was recently identified as a novel genetic locus for a neurodevelopmental disorder. Patients predominantly possess de novo mutations in TLK2, leading to a reduction in its expression or kinase activity. Read more

Role of the endosomal pathway in regulating sleep and circadian rhythms

Ageing and many neurodegenerative disorders are characterised by a progressive loss of neurons in particular brain regions leading to behavioural changes including cognitive decline, sleep disruption and circadian dysregulation. Read more

MSc By Research: Molecular mechanism for Wapl-mediated releasing of cohesin from DNA

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Driving phenotypic plasticity and metastasis in small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Underlying this aggressiveness is intra-tumoural heterogeneity driven by phenotypic plasticity wherein tumour cells transition from a neuroendocrine (NE) to a non-neuroendocrine (non-NE) phenotype. Read more

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