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antimicrobial PhD Projects, Programs & Scholarships

We have 132 antimicrobial PhD Projects, Programs & Scholarships

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  The bacterial protein translocation machinery: a target for new strategies against antimicrobial resistance
  Prof I Collinson
Applications accepted all year round

Funding Type

PhD Type

Bacterial resistance to antibiotics is a major problem affecting millions of people across the world. This severely affects treatment of bacterial infections as strains are emerging that are totally resistant to all clinically used antibiotics.
  MRC Precision Medicine DTP: Deep impact – mining the meningococcal metagenome for antimicrobial resistance to provide public health intelligence data
  Research Group: Dental School
  Prof A Smith, Dr C Cameron
Application Deadline: 8 January 2020

Funding Type

PhD Type

Supervisors. Prof Andrew Smith. Dr Claire Cameron. Prof Martin Maiden. Project summary. This project will focus on meningococcal disease which is a severe and potentially fatal infection of the brain and blood stream with highest incidence in teenagers and young children.
  How acquisition of antimicrobial resistance genes enhance bacterial colonisation and virulence.
  Dr J Morrissey, Prof P W Andrew, Prof J M Ketley
Applications accepted all year round

Funding Type

PhD Type

The human immune system uses antimicrobial metals as part of its defence mechanism. Excess copper is highly toxic and accumulates at sites of infection and acting within macrophages to kill engulfed pathogens.
  The maintenance of virulence and antimicrobial resistance in Shigella
  Prof C Tang
Application Deadline: 10 January 2020

Funding Type

PhD Type

Shigella spp are the main cause for dysentery worldwide, and emerged from commensal Escherichia coli following acquisition of a 210 kb virulence plasmid.
  Synthesis of new types of nanoparticles and their antimicrobial resistance
  Research Group: Quantum, Light & Matter
  Dr A Kanaras
Application Deadline: 31 August 2020

Funding Type

PhD Type

Supervisor. Prof. Antonios Kanaras (Physics). Co-supervisor Prof Myron Christodoulides (Medicine). Project description. Background.
  Changes to prescribing – evaluation of likely impacts on the aquatic environment and AMR potential
  Dr K Helwig, Dr C Hunter, Dr J Spencer
Applications accepted all year round

Funding Type

PhD Type

SCEBE-19-019. After consumption, pharmaceutical residues are excreted by patients, not fully removed in wastewater treatment works, and thus enter the aquatic environment, where they pose a risk to aquatic organisms through chronic exposure.
  (BBSRC DTP) Metals and bacterial virulence: overcoming metal intoxication during infection
  Dr J Cavet, Dr D Linton, Prof J Lloyd
Application Deadline: 31 January 2020

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen, being the leading bacterial cause of human acute gastroenteritis and responsible for an estimated 0.5 billion cases each year.
  Novel synthetic approaches to antimicrobial natural products and investigations of their bioactivity
  Prof A Malkov
Applications accepted all year round

Funding Type

PhD Type

The aim of the project is to develop new highly effective anti-tubercular agents. Previously, it has been established that terpenes isolated from marine organisms possess a number of important antibacterial properties.
  (BBSRC DTP) From mucin biochemistry to pulmonary immunity: How do mucins promote antimicrobial lung defences?
  Prof E Bignell, Prof D Thornton, Dr A Horsley
Application Deadline: 31 January 2020

Funding Type

PhD Type

Respiratory mucus plays multiple essential roles in mammalian lung function, from hydrating the epithelium and supporting gaseous exchange, to expelling inhaled particles and microbes and providing a conduit for innate and adaptive immune signaling.
  Evolution of antimicrobial resistance
  Prof S Lovell
Applications accepted all year round

Funding Type

PhD Type

The increasing prevalence of anti-microbial resistance (AMR) is one of the key health challenges of the 21st centuryThe emergence of AMR is inherently an evolutionary problem.
  MRC DiMeN Doctoral Training Partnership: Design and Optimisation of Red/NIR Fluorescent Dyes for the Assessment of Antimicrobial Susceptibility
  Prof D Kell, Dr G Nixon
Application Deadline: 6 January 2020

Funding Type

PhD Type

The current anti-microbial resistance (AMR) crisis is well documented and the need for a very rapid antibiotic susceptibility test is key to preventing mis-diagnosis and subsequent mis-prescribing.
  MRC DiMeN Doctoral Training Partnership: How to kill a difficult superbug: understanding the evolution of antimicrobial resistance in Clostridioides difficile
  Dr R Fagan, Prof M Brockhurst
Application Deadline: 6 January 2020

Funding Type

PhD Type

Increasing resistance to antibiotics is one of the greatest health challenges facing humanity today. Clostridioides difficile is the primary cause of antibiotic-associated infections in UK hospitals and antibiotic-induced disruption of the gut microbiota is a prerequisite for infection.
  MRC DiMeN Doctoral Training Partnership: How to kill a difficult superbug: understanding the evolution of antimicrobial resistance in Clostridioides difficile
  Dr R Fagan, Prof M Brockhurst
Application Deadline: 6 January 2020

Funding Type

PhD Type

Increasing resistance to antibiotics is one of the greatest health challenges facing humanity today. Clostridioides difficile is the primary cause of antibiotic-associated infections in UK hospitals and antibiotic-induced disruption of the gut microbiota is a prerequisite for infection.
  SCENARIO - Understanding risks and optimising anaerobic digestion to minimise pathogen and antimicrobial resistance genes entering the environment.
  Dr D Saroj
Application Deadline: 24 January 2020

Funding Type

PhD Type

Anaerobic digestion (AD) utilises organic materials to produce energy via biogas while also producing nutrient-rich digestate ideal for application to land as a fertiliser.
  Towards broad spectrum antimicrobial vaccines: uniting automated and enzymatic glycan assembly for the synthesis and bioconjugation of the biofilm exopolysaccharide PNAG
  Dr M A Fascione, Prof G Davies
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. There is a pressing need for antibodies and vaccines of improved efficacy, and improved methods for their production.
  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  EASTBIO: Application of MinION Nanopore sequencing to understand the impact of environmental changes on sentinel indicators of ecosystem health
  Dr E Watson
Application Deadline: 5 January 2020

Funding Type

PhD Type

We are increasingly aware that human, veterinary and environmental health is intricately linked and farming and food production systems must not only be resilient to environmental changes and threats but the systems themselves must also perform with minimal environmental impact.
  Analysis and Treatment of Orthopaedic Pin Site Infections
  Dr J McEvoy
Applications accepted all year round

Funding Type

PhD Type

Pin site infections are a major complication of external fixation of fractures, and bacterial biofilms are known to form on the pin surface.1 This project, in collaboration with Dr Shobana Dissanayeke (RHUL) and St Peter’s Hospital, Chertsey, will investigate bacterial biofilms that have been obtained from percutaneous pins used in orthopaedic fixation frames.
  An integrated bio-based approach for improving food safety and quality
  Dr K Huang
Applications accepted all year round

Funding Type

PhD Type

Microbial issues of food safety are among the most significant constraints for raw or minimally processed products.
  Developing a unified computational framework to evaluate biological, environmental and veterinary performances of livestock farms
  Dr T Takahashi
Application Deadline: 2 December 2019

Funding Type

PhD Type

The project. Livestock is the largest source of protein for humans and its existence is widely considered to be indispensable for various ecosystem services.
  Nanotopographical modulation of bacterial adhesion and biofilm formation
  Prof B Su, Dr M E Barbour
Applications accepted all year round

Funding Type

PhD Type

Surface topography has been known to alter bacterial adhesion and biofilm formation. It has become evident that surface hydrophobicity/hydrophilicity and effective contact area are the two main factors that are responsible for the different bacterial adhesive behaviour on surfaces.
  Equine Veterinary Surveillance Network for the UK Equine Population
  Dr G Pinchbeck, Prof A Radford
Application Deadline: 6 December 2019

Funding Type

PhD Type

In the UK, there are no comprehensive national surveillance data monitoring the extent and emergence of health and disease in the equine population.
  Silver ion-based antimicrobials: mechanisms of toxicity and resistance
  Dr G Mulley, Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"The emergence and persistence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of silver ions.
  Bacterial iron uptake pathways as targets for the development of novel antimicrobials
  Dr M Thomas
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance is an ever increasing problem. Presently it is estimated to be responsible for 700,000 deaths p.a. and it is predicted that this figure will rise to 10 million by 2050.
  EASTBIO: Understanding the pathogenesis of life-threatening Burkholderia cenocepacia infections using blocking antibodies and novel chemistry scaffolds to untangle complex aspects of AMR
  Prof A Porter, Dr S Palliyil, Prof M Jaspars
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Professor Andy Porter (University of Aberdeen). https://www.abdn.ac.uk/people/a.porter. Dr Soumya Palliyil (University of Aberdeen).
  Finding Achilles Heel: Investigating how to control major bacterial pathogens (WEBBERQ20DART)
  Dr M Webber, Prof J Wain
Application Deadline: 2 December 2019

Funding Type

PhD Type

Bacterial infection remains a major cause of morbidity and mortality with hospital acquired infections still common. The increase in numbers of bacterial which are AMR (antimicrobial resistant) makes prevention of infection more important than ever.
  Evaluation of natural plant based botanicals as alternative to therapeutic antibiotics
  Dr C Situ
Applications accepted all year round

Funding Type

PhD Type

It has become widely recognised that antimicrobial resistance (AMR) is one of the biggest health threats that mankind faces, encompassing huge health and economic burdens on governments and societies in every region of the globe.
  Clinical application of machine learning algorithms to determine appropriate antibiotic use in children with Gram-negative bacteria infections
  Dr Y Hsia, Prof C Hughes
Application Deadline: 31 January 2020

Funding Type

PhD Type

Digital health is a growing and productive field in recent years. The application of machine learning (ML) techniques in electronic healthcare databases has been successfully used for clinical diagnosis, outcome prediction, and disease progression.
  Enhancing intracellular delivery of antibiotics using cold atmospheric plasma
  Dr P Flynn, Prof B Gilmore
Application Deadline: 31 January 2020

Funding Type

PhD Type

Atmospheric pressure non-thermal plasma or simply cold plasmas is a partially ionized gas generated at atmospheric pressure, at temperatures suitable for treatment of heat sensitive surfaces such as skin.
  Novel antibiotic candidates against drug-resistant bacteria causing the highest threat to human health
  Prof M Devocelle, Dr D Fitzgerald-Hughes
Application Deadline: 2 December 2019

Funding Type

PhD Type

‘A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century ‘, reported the World Health Organisation (WHO) in 2015.
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