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We have 21 autoimmune PhD Projects, Programmes & Scholarships

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autoimmune PhD Projects, Programmes & Scholarships

We have 21 autoimmune PhD Projects, Programmes & Scholarships

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Early life factors in the development of Juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA) is an autoimmune inflammatory arthritis with disease onset before the age of 16. Children and young people with this condition develop painful swollen joints and untreated it can lead to long term disability. It may also be associated with comorbid conditions such as uveitis. Read more

Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more

Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more

Investigating the impact of inflammation on cardiovascular disease

We are seeking talented, motivated students with a passion for research in cardiovascular inflammation and immune-mediated chronic inflammatory diseases to join the group of Dr Asif Iqbal (Dr Asif Iqbal - Institute of Cardiovascular Sciences - University of Birmingham). Read more
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