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We have 49 cardiac PhD Projects, Programmes & Scholarships

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cardiac PhD Projects, Programmes & Scholarships

We have 49 cardiac PhD Projects, Programmes & Scholarships

Investigating the self-organizing properties of cardiac cells in vivo

The key aims of this PhD project are to use knowledge gathered from high precision in vivo imaging and active matter physics-based theoretical modelling to assess how patterns of cardiac cell contractility drive cardiac tissue curvature. Read more

Bioelectric signalling in cardiac valve development

The key aims of this PhD project are to use knowledge gathered from high precision in vivo imaging and active matter physics-based theoretical modelling to link mechanotransduction to the cellular program leading to functional cardiac valves. Read more

Investigating the mechanisms for cardiac fibrosis development and reversal

Research interests/description of main research theme. Fibrosis is a hard to treat condition of major socioeconomic importance, with ~45% of all deaths in the developed world being attributed to some type of chronic fibro-proliferative disease and is exemplified by heart disease. Read more

Cardiac Harmony: Modelling Heart Beats with Stem Cells and Code

Despite significant advancements in cardiac research, heart disease remains a leading cause of mortality globally. Unexpected cardiac events can occur even in young, fit individuals engaged in routine activities. Read more

The Role of Reactive Sulfur Species in the Ageing Heart

Second Supervisor. Prof Melanie Madhani, University of Birmingham. Background . Ageing is a natural and complex biological process that involves the gradual deterioration of cells, tissues, and organ systems over time, thus leading to an increased susceptibility to diseases and mortality. Read more

MScR - Preserving t-tubule function in adult cardiac myocytes in short-term culture

Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more

Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Disease mechanisms in the heart

We are seeking talented, motivated students with a passion for research in inherited cardiac conditions (cardiomyopathies) and biomechanical stress signalling led by Dr Katja Gehmlich (https://www.birmingham.ac.uk/staff/profiles/cardiovascular-sciences/gehmlich-katja.aspx). Read more

The effect of early-life stress on cardiac function in later life

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

Sex differences in epicardial fat modulation of cardiac function

This project will aim to determine whether structural and physiological properties of epicardial adipose tissue are responsible for the sex differences in human myocardial function and cardiac arrhythmogenicity. Read more

AI Powered Personalized Virtual Heart Modelling

Supervisory Team: Dr Lei Li, Prof. Age Chapman. Project description. In this unique PhD project, we aim to develop advanced AI models for creating cardiac digital twins, i.e., virtual heart models. Read more
Last chance to apply

Towards developing novel actuation method of soft robotic devices towards medical applications

  Research Group: Healthcare Engineering
Beating-heart procedures represent a less invasive alternative to standard open-heart surgery with fewer perioperative complications, and shorter recovery time. Read more

Ageing to Arrhythmias

Cardiac arrhythmias are a leading cause of sudden death and morbidity. This project aims to identify why they occur in the elderly and novel routes to therapies. Read more

Biomechanical signalling in human heart disease

About the Project. The human heart undergoes more than 2 billion beats throughout an individual's lifetime, with its rhythm precisely regulated by signalling events that continuously adapt to the biomechanical stress exerted on the ventricular walls. Read more
Last chance to apply

Biomedical Engineering: Fully Funded Swansea and Boston Scientific Ltd PhD Scholarship: Bioprosthetic Design Evaluation Through Experimental-Computational Techniques

Funding providers: Swansea University's Faculty of Science and Engineering and Boston Scientific Ltd. Subject areas: Experimental Mechanics, Heart Valves, Digital Image Correlation (DIC), Particle Image Velocimetry (PIV), Biomechanics, Fluid-Structure Interaction. Read more

Investigating the link between chronic kidney disease and cardiovascular disease.

Research interests/description of main research theme.  Patients with chronic kidney disease are 40% more likely to develop cardiovascular disease, however, mechanisms driving the cardiovascular pathogenesis are unclear. Read more

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Role of RyR2 posttranslational modification in arrhythmias

Cardiac arrhythmias remain the leading cause of death in patients with heart disease. An important trigger for arrhythmias is the inappropriate opening of the cardiac ryanodine receptor (RyR2). Read more

Exploring cardio-renal-metabolic interactions in patients with heart failure

Recent years have highlighted the connections and shared pathophysiology between heart failure, renal impairment, diabetes and obesity, particularly with the evidence of benefit in all of these areas with SGLT2 inhibitors and GLP1-receptor agonists. Read more

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