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cell culture PhD Projects, Programs & Scholarships

We have 399 cell culture PhD Projects, Programs & Scholarships

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  Quantitative Evaluation of Bioscaffold Cell Culture by Images from Confocal Laser Scanning Microscopy
  Prof J Sun, Dr K Black, Dr K Huang
Applications accepted all year round

Funding Type

PhD Type

Micro to nano scale three-dimensional (3D) bioscaffold is widely used in cell biology research and tissue engineering. Such bioscaffolds can closely resemble the architectural microenvironment of natural tissue, compared to standard two-dimensional cell culture, promote the varied levels of cell proliferation.
  Mechanistic analysis of neurodevelopmental disorders caused by mutations in the gene RAC1
  Dr T Millard, Dr S Banka
Applications accepted all year round

Funding Type

PhD Type

RAC1 is a signalling protein that regulates many cellular processes and is essential during embryonic development. We recently discovered a novel genetic disease called RAC1-related neurodevelopmental disorder (RRND) that results from mutations in the RAC1 gene.
  (BBSRC DTP CASE) Jellyfish-collagen hydrogels for culture and differentiation of human mesenchymal stem cells and 3D cartilage bioprinting
  Dr J Bella, Dr S Richardson, Dr M Domingos
Application Deadline: 31 January 2020

Funding Type

PhD Type

We are looking for an enthusiastic and talented graduate from a relevant biomedical or materials science degree to develop next-generation, sustainable collagen-based scaffolds for stem cell culture, differentiation, and 3D bioprinting, aimed at tissue regeneration applications.
  Development of functionalised exosomes for personalised precision medicine in the treatment of cancer - a nanomedicine platform
  Research Group: Biomedical Research Group
  Dr P Dyer, Dr C O'Kane, Prof C Parris
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Dynamic cell fate decisions: linking mechanical signals and protein expression dynamics in the developing eye to understand human developmental disorders
  Dr Cerys Manning, Prof N Papalopulu
Applications accepted all year round

Funding Type

PhD Type

Inherited developmental disorders account for much of childhood visual impairment. Development of the eye requires cell fate decisions that balance stem cell proliferation and differentiation.
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
  Investigating metabolic changes in neurodegeneration
  Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round

Funding Type

PhD Type

This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
  Non-viral gene therapy to prevent cartilage degeneration in Osteoarthritis
  Dr C Curtain, Dr O Kennedy, Dr F O'Brien
Application Deadline: 2 December 2019

Funding Type

PhD Type

Osteoarthritis (OA) is the most common form of joint disease, affecting one in five people in the EU and results in activity limitations for approximately one in ten.
  EASTBIO: Investigating the effect of underutilised, emerging, polyphenol-rich berries on cardiometabolic health.
  Dr N Hoggard, Dr V Rungapamestry, Dr G McDougall
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Dr Nigel Hoggard (University of Aberdeen). http://www.abdn.ac.uk/rowett/research/nigel-hoggard.php. Dr Vanessa Rungapamestry (University of Aberdeen).
  Microtubule motors in cell migration and integrin trafficking
  Prof V Allan, Prof P Woodman, Dr P Caswell
Applications accepted all year round

Funding Type

PhD Type

Cell migration is vital for the development and health of multicellular organisms. However, enhanced cell migration is also a hallmark of cancer cells, and contributes greatly to metastasis.
  (MCRC Non-Clinical) A synthetic lethal strategy to target cell viability to different levels of Notch activity
  Dr M Baron, Dr R Clarke, Prof K R Brennan, Prof S Hubbard
Application Deadline: 1 December 2019

Funding Type

PhD Type

Project summary. Notch is a transmembrane localised signalling receptor utilised both in development and adult stem cell regulation and whose misregulation is frequently involved in different human cancers.
  Role of the centrosome and cilia in development
  Dr C Wilkinson
Applications accepted all year round

Funding Type

PhD Type

My research interest lies in the roles of centrioles and associated proteins, as parts of the centrosome and cilium, in early vertebrate development, using zebrafish embryos as a model system.
  MRC DiMeN Doctoral Training Partnership: Nanoinjection: a novel single molecule technique to study alpha-synuclein amyloid toxicity inside neurons
  Dr E W Hewitt, Dr P Actis, Prof S E Radford
Application Deadline: 6 January 2020

Funding Type

PhD Type

Project Aims. The aim of this project is to use nanoinjection to perform the quantitative delivery of alpha-synuclein fibrils or oligomers into the cytoplasm of neurons and then determine how many of each is required to induce cellular stress and death.
  Inhibitors and probes for carbohydrate-active enzymes
  Dr L Willems
Applications accepted all year round

Funding Type

PhD Type

The field of chemical biology aims to design and synthesize chemical tools (such as inhibitors, substrate mimics, or enzyme probes) to answer fundamental questions in biology.
  Engineering Medicine Manufacture Processes for Cell and Stem Cell Based Therapies
  Dr R Thomas
Applications accepted all year round

Funding Type

PhD Type

Cell and Stem Cell based therapies are revolutionising medical treatment. Immunotherapies such as CAR-T cells are effectively treating previously terminal diseases and are poised to reach mass markets.
  Precision Medicine DTP - Connecting Molecular Profiles to Phenotype: A Proteomic Resource for Assigning Cell Cycle and Senescent States
  Research Group: Institute of Cell Biology
  Dr T Ly, Dr A Lindqvist
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. A hallmark of cancer is aberrant cell cycle control leading to pathological cell proliferation. Cell cycle progression is controlled by key kinases, such as cyclin-dependent kinases (CDKs) and polo-like kinases (PLKs).
  Understanding and minimizing radiation damage in breast tissues
  Dr M Sherratt, Miss C Kirwan, Prof S Cartmell
Applications accepted all year round

Funding Type

PhD Type

Human beings are subjected to many forms of radiation both natural (principally ultraviolet radiation [UVR]) and artificial (diagnostic and therapeutic X-rays).
  Impact of Inflammatory Signals on the Regenerative, Anti-inflammatory and Immunomodulatory Potential of Human Mesenchymal Stem Cells and their Secretome
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Adult multipotent stem cells can be easily isolated from a variety of adult human tissues and organs including bone marrow and adipose tissue.
  Small molecule probes to study human enzymes involved in muscular dystrophy
  Dr L Willems, Dr M A Fascione
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Proteins on the surface of cells are often modified with diverse, complex carbohydrate structures. These carbohydrates, named glycans, play central roles in biology by regulating, for instance, cell recognition and signalling events.
  Species-specific remodelling of host cells in the most pathogenic malaria causing parasite Plasmodium falciparum
  Dr M Treeck
Application Deadline: 23 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Moritz Treeck’s Group based at the Francis Crick Institute (the Crick). The most severe form of human malaria is caused by the parasite Plasmodium falciparum.
  Expanded potential stem cells for regenerative medicine, immunotherapy, and biotechnology
  Prof P Liu
Applications accepted all year round

Funding Type

PhD Type

Embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells) are pluripotent and thus hold great promise in regenerative medicine, studying disease mechanisms and drug discovery.
  Correlating electrical and imaging signals to better understand cell state
  Prof P Verkade, Prof J Kiely, Prof R Luxton
Application Deadline: 2 December 2019

Funding Type

PhD Type

The ability to monitor and influence the physiological state of a cell (population) is of critical importance not just for reproducible results in academia but especially in the pharmaceutical industry.
  Regulation of the tissue degradation in osteoarthritis
  Research Group: Biomedical Research Group
  Dr J Bird, Dr P Coussons, Dr F Savage
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  The investigation of a novel peptide delivery platform for the manipulation of platelet function
  Research Group: Biomedical Research Group
  Dr P Dyer, Dr N Pugh
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks
  Dr A Antonysunil
Applications accepted all year round

Funding Type

PhD Type

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children.
  The role of extracellular vesicles and glycosylation in breast cancer metastasis
  Prof D Carter, Prof S Brooks
Application Deadline: 31 December 2019

Funding Type

PhD Type

Oxford Brookes University. Faculty of Health and Life Sciences,. Department of Biomedical and Medical Sciences. 3 Year, full-time PhD studentship.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  Wellcome Trust 4-year PhD in Dynamic Molecular Cell Biology in Bristol

Funding Type

PhD Type

Our Dynamic Molecular Cell Biology 4-Year PhD Programme trains students to investigate dynamic mechanisms from molecular through to organismal level using cutting edge imaging technologies combined with biochemical and biophysical interrogation.
  EASTBIO Single cell analysis of invasion and establishment in the intracellular pathogen Theileria annulata
  Dr L Morrison, Dr M Hassan, Dr T Connelly
Application Deadline: 5 January 2020

Funding Type

PhD Type

Royal (Dick) School of Veterinary Studies / The Roslin Institute. During infections with intracellular pathogens, successful invasion and establishment in a recipient cell is the key event.
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
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