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circadian clock PhD Projects, Programs & Scholarships

We have 20 circadian clock PhD Projects, Programs & Scholarships

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  EASTBIO Investigating the role of the circadian clock in antiviral defence
  Research Group: Institute of Molecular Plant Sciences
  Dr Attila Molnar
Application Deadline: 5 January 2020

Funding Type

PhD Type

Second Supervisor. Dr Andrew Love Hutton Institute. Circadian rhythm is an approximately 24-hour cycle in the physiological processes of living organisms, which is driven by the circadian clock (1).
  Investigating the role of the circadian clock in antiviral defence
  Research Group: Institute of Molecular Plant Sciences
  Dr Attila Molnar
Application Deadline: 5 January 2020

Funding Type

PhD Type

Circadian rhythm is an approximately 24-hour cycle in the physiological processes of living organisms, which is driven by the circadian clock (1).
  Mapping the circadian clock-dependent regulation of the secretory pathway
  Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round

Funding Type

PhD Type

The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
  Dissecting quantitative variation in the plant circadian clock
  Prof S J Davis, Dr D Ezer, Dr M Knight
Application Deadline: 5 January 2020

Funding Type

PhD Type

The seasonal timing of growth is critical for plant performance. The circadian. clock holds a key place in such seasonal adjustment as crop adaptation to new.
  Crosstalk between the circadian clock and innate immune system in plants
  Research Group: Institute of Molecular Plant Sciences
  Dr G van Ooijen, Dr S Spoel
Application Deadline: 5 January 2020

Funding Type

PhD Type

Involvement of the circadian clock in many aspects of human health is well recognised, but circadian input in plant immunity is not as well understood.
  EASTBIO Crosstalk between the circadian clock and innate immune system in plants
  Research Group: Institute of Molecular Plant Sciences
  Dr G van Ooijen, Dr S Spoel
Application Deadline: 5 January 2020

Funding Type

PhD Type

Involvement of the circadian clock in many aspects of human health is well recognised, but circadian input in plant immunity is not as well understood.
  Understanding how altered GABA signalling in the brain’s master clock contributes to circadian rhythm disruption in Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr M Belle
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Mino Belle, Institute of Biomedical and Clinical Science, Medical School, University of Exeter. Dr James Hodge, Faculty of Life Sciences, University of Bristol.
  Transcription factors mediating light input to the Arabidopsis circadian clock
  Dr P Devlin
Applications accepted all year round

Funding Type

PhD Type

The circadian clock is tightly tied to the light environment. Transcriptional feedback loops are able to generate a self-sustaining rhythm of approximately 24 hours which impinges on almost every aspect of physiology in higher organisms.
  The circadian clock in the ageing plant
  Dr D Ezer, Prof S J Davis
Application Deadline: 5 January 2020

Funding Type

PhD Type

Plants respond to environmental signals in a time-of-day dependent manner,. but we do not yet know how this process is affected by age.
  Rhythms under your skin: Enhancing vaccine efficiency using a state-of-the-art dissolvable intradermal microneedle patch and harnessing the skin dendritic cell circadian clock
  Dr A Curtis, Dr R Donnelly
Application Deadline: 2 December 2019

Funding Type

PhD Type

Vaccination is the greatest success story of modern medicine with the WHO estimating 10 million deaths were prevented by vaccines between 2010 and 2015.
  (BBSRC DTP) The role of clock dysfunction in obesity-related inflammation and insulin resistance
  Dr D Bechtold, Dr S Cruickshank, Dr I Iqbal
Application Deadline: 31 January 2020

Funding Type

PhD Type

Obesity is one of the biggest challenges to public health in the UK and across much of the world. The major threat is in obesity-related metabolic disturbances, which drive insulin resistance, type-2 diabetes, and cardiovascular disease.
  Modelling the effect of ageing on Drosophila and mouse clockneurons
  Dr J Hodge, Prof K Tsaneva-Atanasova, Prof H Piggins
Application Deadline: 2 December 2019

Funding Type

PhD Type

All organisms are subject to daily environmental changes caused by the earth’s rotation leading to the evolution of circadian clock mechanisms that regulate changes in behaviour, physiology and metabolism across the day to ensure their timely occurrence and allowing environmental adaption.
  Circadian control of energy metabolism and inflammation
  Prof D Ray
Application Deadline: 10 January 2020

Funding Type

PhD Type

Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, Circadian mechanisms regulate most mammalian physiology, with particular importance in the regulation of innate immunity, through the macrophage in particular, and energy metabolism, regulating liver, adipose and muscle.
  Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism
  Dr D Bechtold, Prof D Ray
Applications accepted all year round

Funding Type

PhD Type

24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g.
  How does the macrophage molecular clock modulate thrombogenesis?
  Dr R Preston, Dr A Curtis
Application Deadline: 2 December 2019

Funding Type

PhD Type

Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide. A common feature of CVD is vascular inflammation that in turn promotes blood clotting and thrombosis.
  Unravelling and modelling endogenous controls of plant respiration. PhD in Geography (NERC GW4+ DTP)
  Prof S Sitch
Application Deadline: 6 January 2020

Funding Type

PhD Type

Lead Supervisor. Dr Stephen Sitch, Department of Georgraphy, College of Life and Environmental Sciences, University of Exeter. Additional Supervisors.
  EASTBIO Time to hatch and feed: Neuroendocrine mechanisms underpinning appetite in birds
  Prof S Meddle, Prof G Leng
Application Deadline: 5 January 2020

Funding Type

PhD Type

Royal (Dick) School of Veterinary Studies / The Roslin Institute. Aim. This fascinating PhD project will investigate the crucial time in every bird’s life.
  Fly, mouse and computational modelling of the effect of Alzheimer’s disease on clock neuron excitabilit
  Dr J Hodge, Prof K Tsaneva-Atanasova
Application Deadline: 25 November 2019

Funding Type

PhD Type

Alzheimer’s disease (AD) involves amyloid-B and tau accumulation resulting in memory, sleep and circadian rhythm loss. How this occurs is unknown hampering the development of effective AD drugs.
  (MRC DTP) The importance of 24h rhythms in the gut microbiome for immunity
  Dr J Gibbs, Dr M Hepworth, Prof K Else
Application Deadline: 15 November 2019

Funding Type

PhD Type

The gut microbiome is a collection of trillions of organisms. These bacteria and the metabolites they produce (through the breakdown of dietary components) play a critical role in the maintenance of immunity.
  Combatting brain and body ageing through exercise
  Prof H Piggins, Dr K Ellacott, Prof A E Pickering
Application Deadline: 2 December 2019

Funding Type

PhD Type

It is popularly accepted that the way to a long life is through regular exercise, good sleeping habits and a healthy diet.
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