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clinical trial PhD Projects, Programs & Scholarships

We have 57 clinical trial PhD Projects, Programs & Scholarships

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  Assessing the generalisability of trial findings using large orthopaedic population studies #NDORMS-2020/5
  Assoc Prof J Cook, Prof X Griffin, Assoc Prof B Ollivere
Application Deadline: 10 January 2020

Funding Type

PhD Type

Randomised trials (RCTs) are widely accepted as the preferred approach to evaluating health care interventions. However, the clinical relevance and generalisability of the findings are often disputed.
  Patient experience of the Mesothelioma Stratified Therapy Trial (MiST): a qualitative study
  Prof A Tod, Dr B Taylor
Applications accepted all year round

Funding Type

PhD Type

This PhD provides a unique opportunity for a student to conduct a qualitative patient experience health services research study within a complex stratified clinical trial for people with malignant mesothelioma (MM), the Mesothelioma Stratified Therapy Trial (MiST).
  Development and Implementation of Efficient Adaptive Designs in Early Phase Oncology Trials for Novel Agents
  Prof C Yap, Prof J Bliss
Application Deadline: 17 November 2019

Funding Type

PhD Type

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes. We are committed to attracting and developing the best minds in the world to join us in our mission—to make the discoveries that defeat cancer.
  Use of EUROQOL-5D (EQ-5D) in orthopaedic trauma trials #NDORMS-2020/4
  Assoc Prof J Cook, Prof X Griffin
Application Deadline: 10 January 2020

Funding Type

PhD Type

Health related quality of life is commonly measured in clinical research studies including Randomised Controlled Trials (RCTs). Perhaps the most commonly used to do this is the Euroqol-5 dimensions (EQ-5D) questionnaire (1).
  (MCRC Clinical) Developing circulating and imaging biomarkers towards personalised radiotherapy in lung cancer
  Prof C Faivre-Finn, Dr G Price, Prof C Dive
Application Deadline: 1 December 2019

Funding Type

PhD Type

Project summary. Approximately a third of Non-Small Cell Lung Cancer cases are locally-advanced (LA-NSCLC) at presentation (~13,000 pts a year in the UK) with the majority being unsuitable for curative surgery.
  Evolutionary dynamics of MEK inhibitor sensitivity and resistance in diffuse midline glioma
  Dr C Jones, Dr O Rossanese
Application Deadline: 17 November 2019

Funding Type

PhD Type

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes. We are committed to attracting and developing the best minds in the world to join us in our mission—to make the discoveries that defeat cancer.
  Assessing the ability of hypoxic pre-conditioning to enhance the immunomodulatory capacity of canine cardiac stem cell as a bridge to the treatment of dilated cardiomyopathy.
  Dr D Connolly
Applications accepted all year round

Funding Type

PhD Type

Dilated Cardiomyopathy (DCM) is a common and serious disease, which imposes a significant welfare burden in dogs. DCM is particularly well characterise in Dobermans where a 58.8% cumulative prevalence has been identified in European lines.
  Improving statistical methods for trial emulations using observational data
  Dr L Su, Dr S Seaman
Application Deadline: 7 January 2020

Funding Type

PhD Type

Randomised controlled trials (RCTs) are regarded as the gold standard for estimating causal effects of treatments on health outcomes.
  Four-Year Wellcome Trust PhD Programme in Translational Neuroscience

Funding Type

PhD Type

The University of Edinburgh invites applications to the Wellcome Trust funded 4-year PhD programme in Translational Neuroscience.
  PhD and Clinical PhD Fellow opportunities at the UKRI Centre Artificial Intelligence for Healthcare

Funding Type

PhD Type

Our vision is to train PhD students to become next-generation innovators in Artificial Intelligence (AI) applied to Healthcare, and we are inviting excellent, suitably qualified graduates with strongest AI-related skills and strong interest in healthcare.
  Pump Design and Development for Intra-Ventricular Balloon Pump
  Dr J Pauls
Applications accepted all year round

Funding Type

PhD Type

The Critical Care Research Group (CCRG), based at the The Prince Charles Hospital (TPCH) in Brisbane, Australia, is seeking highly motivated, skilled and committed PhD candidates to join our multidisciplinary and international research team to commence a PhD project.
  GW4 BioMed MRC DTP PhD studentship: Causal inference methods for randomised trials
  Dr J Bartlett
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  (MCRC Non-Clinical) Assessing the impact of oxygen tension on the generation of cancer immunity
  Prof J O'Connor, Dr J Honeychurch, Prof K Williams
Application Deadline: 1 December 2019

Funding Type

PhD Type

Project summary. The importance of T-cell immunity to cancer outcome is becoming increasingly well-recognised.
  Cathepsin Z as a novel potential biomarker for osteoporosis
  Dr D Barraclough, Prof L Ranganath
Applications accepted all year round

Funding Type

PhD Type

Supervisors. Dr. Dong Barraclough, Professor Lakshminarayan Ranganath and Professor Sobhan Vinjamuri.
  Integrative computational analysis of molecular and clinical data to dissect heterogeneity of therapy response in sarcomas
  Dr P Huang, Dr M Cheang, Dr A Sadanandam
Application Deadline: 17 November 2019

Funding Type

PhD Type

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes. We are committed to attracting and developing the best minds in the world to join us in our mission—to make the discoveries that defeat cancer.
  MRC DiMeN Doctoral Training Partnership: Investigating the mechanisms leading to CHK1 inhibitor resistance in cancer therapy
  Prof N Perkins, Prof S Rocha, Dr J Hunter
Application Deadline: 6 January 2020

Funding Type

PhD Type

DNA replication stress results from stalled DNA replication forks and is a feature of cancer cells, where it can lead to the genomic instability driving tumorigenesis.
  Identifying novel treatment options for ovarian carcinosarcoma
  Dr H Barker
Application Deadline: 31 January 2020

Funding Type

PhD Type

Location. The Walter and Eliza Hall Institute of Medical Research, University of Melbourne. Supervisors. Prof C. Scott, Dr H. Barker.
  PhD Research Fellow in Biomarker Discovery
  Prof G Alves, Dr J Maple-Grødem
Application Deadline: 17 November 2019

Funding Type

PhD Type

The University of Stavanger invites applicants for PhD fellowships in Biomedicine as part of the GCase-Responders Across Neurodegenerative Diseases (the GRAND project).
  Does Histone Deacetalyse Inhibition Reduce Atherosclerosis and Stroke Risk (PhD only) 
  Prof H Markus
Application Deadline: 3 December 2019

Funding Type

PhD Type

The Cambridge Stroke Group led the identification of the HDAC9 (histone deacetalyse 9) gene as a risk factor for stroke. The association is specific for large artery stroke due to atherosclerosis.
  Decreasing the side effects from breast cancer treatment
  Dr M Aznar, Prof M Van Herk, Prof C West
Applications accepted all year round

Funding Type

PhD Type

Radiotherapy is an important part of a successful treatment for many women with breast cancer, but it can lead to side effects. Women often complain about skin burns, a stiff shoulder or a swollen arm.
  Combining randomised controlled trials and population based ‘omic research: an exploration of how excessive body weight causes disease
  Dr N Timpson
Application Deadline: 25 November 2019

Funding Type

PhD Type

Additional research and training funding is available over the course of the programme. This will cover costs such as research consumables, courses, conferences and travel.
  MRC DiMeN Doctoral Training Partnership: Systems-level understanding of calcium dynamics in cardiac cells, and functional effects of their modification in heart failure
  Dr M.A. Colman, Dr A.P. Benson
Application Deadline: 6 January 2020

Funding Type

PhD Type

The mechanical function of the heart is driven by electrical activity through the process of excitation-contraction coupling. Intracellular calcium (Ca2+) signalling is a critical component of this coupling.
  Longitudinal trajectories of renal function, and dynamic prediction of progression to end-stage renal disease: a data-driven analysis and validation using regression and machine learning methods in a bi-national population-based cohort #NDORMS-2020/1
  Prof D Prieto-Alhambra, Dr V Strauss, Dr S Khalid, Dr D Robinson
Application Deadline: 10 January 2020

Funding Type

PhD Type

1. Prof Daniel Prieto-Alhambra. 2. Dr V Strauss. 3. Dr Sara Khalid. 4. Dr Danielle Robinson. 5. Dr Laurie Tomlinson. There is a scarcity of data on the natural history of chronic kidney disease (CKD) in the general population, and on markers of rapid progression to end-stage renal disease (ESRD).
  Strategies of handling missing data in federated data network #NDORMS 2020/9
  Prof D Prieto-Alhambra, Dr V Strauss, Dr A Delmestri, Prof I Petersen
Application Deadline: 10 January 2020

Funding Type

PhD Type

The use of electronic healthcare data is increasingly being proposed as a source of evidence to support drug development and regulatory decision making but also to understand the pathogenesis of diseases.
  MRC DiMeN Doctoral Training Partnership: How to kill a difficult superbug: understanding the evolution of antimicrobial resistance in Clostridioides difficile
  Dr R Fagan, Prof M Brockhurst
Application Deadline: 6 January 2020

Funding Type

PhD Type

Increasing resistance to antibiotics is one of the greatest health challenges facing humanity today. Clostridioides difficile is the primary cause of antibiotic-associated infections in UK hospitals and antibiotic-induced disruption of the gut microbiota is a prerequisite for infection.
  MRC DiMeN Doctoral Training Partnership: How to kill a difficult superbug: understanding the evolution of antimicrobial resistance in Clostridioides difficile
  Dr R Fagan, Prof M Brockhurst
Application Deadline: 6 January 2020

Funding Type

PhD Type

Increasing resistance to antibiotics is one of the greatest health challenges facing humanity today. Clostridioides difficile is the primary cause of antibiotic-associated infections in UK hospitals and antibiotic-induced disruption of the gut microbiota is a prerequisite for infection.
  PhD Research Fellow in Neuroimaging / Machine learning
  Dr K Oppedal, Prof G Alves
Application Deadline: 17 November 2019

Funding Type

PhD Type

The University of Stavanger invites applicants for PhD fellowships in Biomedicine as part of the GCase-Responders Across Neurodegenerative Diseases (the GRAND project).
  TRANS-CASPS: Translational studies in Cedrianib in Alveolar Soft Part Sarcoma (CASPS) trial.
  Dr C Jones, Dr P Huang
Application Deadline: 17 November 2019

Funding Type

PhD Type

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes. We are committed to attracting and developing the best minds in the world to join us in our mission—to make the discoveries that defeat cancer.
  (MRC DTP) Zinc deficiency: a potential contributor to post-stroke complications
  Dr C Lawrence, Prof D Brough, Prof C Smith, Prof S Allan
Application Deadline: 15 November 2019

Funding Type

PhD Type

Stroke remains a leading cause of death and disability worldwide with limited treatment options. In addition to the immediate and common symptoms of stroke such as limb weakness and speech problems, stroke patients often develop complications.
  Tyrosine kinase inhibitors conjugated tumour targeting dyes for the treatment of glioblastoma.
  Dr J Jose, Dr P Choi
Applications accepted all year round

Funding Type

PhD Type

Glioblastoma (GBM) remains a lethal and difficult to treat cancer with a dismal outcome. Although we have a better understanding of the disease progression, a concurrent increase in therapeutic intervention is lagging.
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