We have 32 colorectal PhD Projects, Programmes & Scholarships

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colorectal PhD Projects, Programmes & Scholarships

We have 32 colorectal PhD Projects, Programmes & Scholarships

Causal risk factors and biological mechanisms for colorectal cancer risk

University of Bristol Bristol Medical School

Rationale. Diet and lifestyle are likely to play an important role in colorectal cancer risk; obesity, low levels of physical activity, red and process meat consumption and low intake of dietary fibre have all been shown to predict colorectal cancer risk. Read more

Supervisors: Dr S Lewis, Dr KT Tsilidis

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Biological significance, predictive value and targeting of cell surface antigens in colorectal cancer

Kingston University Faculty of Health, Science, Social Care and Education

Despite major advances in its early detection, preventive measures and therapeutic options, colorectal cancer remains one of the most commonly diagnosed cancer and a leading cause of cancer deaths worldwide. Read more

Supervisor: Dr S. K Khelwatty

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Investigating intrinsic and extrinsic mechanisms driving plasticity in colorectal cancer metastasis

Queen Mary University of London Barts and The London School of Medicine and Dentistry

This CRUK-funded project will commence in September 2024 and has funding for 4 years. The successful candidate will be based at Barts Cancer Institute, Faculty of Medicine and Dentistry (FMD), Charterhouse Square in the City of London. Read more

Supervisors: Dr M Efremova, Dr G Ficz

24 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Methylation profiling in colorectal cancer and its relation to other molecular and clinical characteristics

Charles University Second Faculty of Medicine

Methylation profiling in colorectal cancer and its relation to other molecular and clinical characteristics. Second Faculty of Medicine, Department of Paediatric Haematology and Oncology. Read more

Supervisor: Dr L Boublikova

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

University of Leeds Faculty of Medicine and Health

Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more

Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley

Year round applications PhD Research Project Self-Funded PhD Students Only

An investigation on the association of high risk human papillomavirus (HPV) types with colonic adenomata and adenocarcinomas: a UK population based study

Kingston University Faculty of Health, Science, Social Care and Education

This PhD studentship invites application for a study “investigating the association between high risk human papillomavirus (HPV) types and colonic adenomata and adenocarcinomas in a UK population”. Colorectal cancer (CRC) is an important public health problem worldwide occupying most frequent causes of cancer-related mortality. Read more

Supervisor: Dr H Ashrafi

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Last chance to apply

Preventing Ovarian Cancer, Colorectal Cancer, and Related Metastases

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) will perform basic molecular biology research on in vitro and in vivo cancer models at the Medical University of Vienna, Austria. Read more

Supervisors: Dr MSch Schepelmann, Prof E K Kallay

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr MI Khot, Prof A Paradkar, Prof D Jayne

Year round applications PhD Research Project Self-Funded PhD Students Only

Oncology: Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Leeds Faculty of Medicine and Health

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr I Knot, Prof D Jayne

Year round applications PhD Research Project Self-Funded PhD Students Only

Unravelling the role of genotoxic E. coli in colorectal cancer (SCHULLERS_U24BIGC)

University of East Anglia Norwich Medical School

Primary supervisor - Dr Stephanie Schüller. Secondary supervisor - Prof Nathalie Juge. Colorectal cancer (CRC) is the third most common and second most fatal cancer globally. Read more

Supervisor: Dr S Schüller

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Development of a Low-Cost Autonomous Device for Colorectal Cancer Screening and Treatment

University of Dundee School of Science and Engineering

We are excited to announce a fantastic opportunity to join our dynamic team at the Endorobotics Lab, led by Dr. Luigi Manfredi, in the School of Medicine at the University of Dundee. Read more

Supervisor: Dr L Manfredi

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Investigating the role of dietary fructose in the development of early-onset colorectal cancer

University of Bristol Bristol Medical School

Project Background. This project will investigate the role of fructose in the development of early-onset colorectal cancer (EOCRC) in adults <50 years. Read more

Supervisors: Dr E Vincent, Dr A Chambers, Dr R Richmond, Dr NM Murphy

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

The role of gut microbiota in regulating tumour cell metabolism and malignant progression

University of the West of England, Bristol College of Health, Science and Society

We are inviting applicants for the PhD position in ‘The role of gut microbiota in regulating tumour cell metabolism and malignant progression’. Read more

Supervisor: Dr D Qualtrough

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School

Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more

Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

PhD Scholarship in Deep Learning for Medical Video Analysis and Understanding

City, University of London Department of Computer Science

AI has the potential to revolutionise healthcare, providing tools for fast and reliable analysis and interpretation of medical data. Read more

Supervisor: Dr G Tarroni

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Pectin supplementation to reduce gut and systemic inflammation and improve liver, muscle and gastrointestinal outcomes

University of Nottingham School of Medicine

A quarter of the world's population has metabolic dysfunction-associated steatotic liver disease, (which used to be known as non-alcoholic fatty liver disease). Read more

Supervisors: Prof G Aithal, Dr J Grove, Dr KR Rollins, Prof AMV Valdes

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

Addressing non-acceptance of colonoscopy within the Bowel Screening Programme

University of Dundee School of Medicine

Population-based screening programmes have reduced colorectal cancer (CRC)-specific mortality. However, non-completion of screening episodes is a global problem. Read more

Supervisors: Dr C Mowat, Dr A Farre

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Small molecule cancer drug discovery targeting resistant disease.

Cardiff University Cardiff School of Pharmacy and Pharmaceutical Sciences

Despite continuous advances in targeted cancer therapy in recent years, there remains a major challenge to combat drug resistance and poor levels of efficacy in areas of unmet medical need, such as advanced colorectal and breast cancer. Read more

Supervisor: Prof A Westwell

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health

RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more

Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar

Year round applications PhD Research Project Self-Funded PhD Students Only

Last chance to apply

Communicating benefits of population vaccination and screening programmes for optimal uptake and improved longevity in areas with regional disparities.

Atlantic Technological University Research

The Postgraduate Research Programme Translational Health Research Innovation preVention & Equity (THRIVE) offers 12 PhD research scholarships to commence in 2024. Read more

Supervisors: Dr LMB McBride, Dr R Burns, Dr GG Gliga, Dr CH Heaney

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Cancer Epigenetics project

University of Otago Department of Pathology

Broad Project Summary: Cancer is a leading cause of morbidity and mortality worldwide. Epigenetic changes are now recognised as a hallmark feature of cancer, but our understanding of factors that are responsible for tumour spread still remains limited. Read more

Supervisor: Assoc Prof A Chatterjee

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

Is there a role for Fusobacterium nucelatum, candida or HV16 in oral disease progression?

University of Dundee Dental School

Oral squamous cell carcinoma (OSCC) accounts for over 90% of all oral cancers and is generally considered the 8th most common cancer worldwide [1]. Read more

Supervisors: Prof M Macluskey, Dr D H Edwards

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more

Supervisors: Dr S Shnyder, Dr S Kantamneni

Year round applications PhD Research Project Self-Funded PhD Students Only

Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more

Supervisors: Dr S Shnyder, Prof S El-Khamisy

Year round applications PhD Research Project Self-Funded PhD Students Only

Hepatic Models to personalise cancer chemotherapy

University of Liverpool Department of Pharmacology and Therapeutics

The most commonly used chemotherapy regimens for colorectal cancer with liver metastases are oxaliplatin combined with 5-FU and leucovorin, i.e. Read more

Supervisors: Prof C Goldring, Dr A Chadwick, Prof IC Copple, Dr S Pushpakom

Year round applications PhD Research Project Self-Funded PhD Students Only

Regulation of CaaX protein processing

Queen’s University Belfast School of Pharmacy

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types, as well as the migration of a range of cancer cells (NSCLC, breast, ovarian, osteosarcoma). . Read more

Supervisor: Dr J Burrows

Year round applications PhD Research Project Self-Funded PhD Students Only

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

Estimating the global cancer burden due to low levels of physical activity

University of Bristol Bristol Medical School

Rationale. Around 40% of all cancers are thought to be avoidable by modification of lifestyle factors. Obesity has been found to be a risk factor for several cancers and was estimated to have caused around 3.6% of all new cancers which occurred in 2012. Read more

Supervisors: Dr S Lewis, Prof R Martin, Dr R Pulsford, Prof R Jago, Dr FB Bray

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Repurposing and enriching cardiovascular risk prediction model to identify people at risk of cancer – UCL (part of Health Data Research UK’s Big Data for Complex Disease Driver Programme)

Health Data Research UK Big Data for Complex Diseases (BDCD)

Risk-stratified management of cardiovascular disease (CVD), where people without established disease receive preventative interventions and monitoring based on their 10-years predicted risk, has been highly successful to ensure healthcare resources are allocated to those most likely to benefit. Read more

Supervisor: Dr FS Schmidt

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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