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We have 130 death PhD Projects, Programmes & Scholarships

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death PhD Projects, Programmes & Scholarships

We have 130 death PhD Projects, Programmes & Scholarships

Cancer: Inhibiting cell metabolism to enhance tumour cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Probing Death Decisions from Morphogen Gradient Fields

Morphogen gradient scaling is one of the hottest fields in developmental biology at the moment. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt, so that organs of different sizes show morphological structures which are proportioned. Read more

Inducing ferroptotic death to kill cancer cells

Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more

Updating the background characteristics and risk factors associated with Sudden Infant Death Syndrome (SIDS) to inform risk-reduction messages and help target vulnerable families

Our team has been instrumental in reducing the number of cot deaths (SIDS or Sudden Infant Death Syndrome) in England & Wales by 90% over the last three decades.[1] The remaining 2-300 unexpected infant deaths per year show a marked inequality, largely coming from socio-economically deprived communities. Read more

Epilepsy and the ageing brain

Our ability to remember ‘where I put my car keys today’ instead of ‘where I put them yesterday’ depends on a computational process called pattern separation. Read more

Investigating the innate immune response in RSV and HMPV infection

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£46,000 total). Read more

Biomechanical investigation of minimally assisted vs self and conventional extrication of people form vehicles following road traffic collisions

Road traffic collisions are a leading cause of death worldwide; indeed, road traffic injuries are the number one cause of death for children and young adults aged 5-29 years, and, more than 90% of these deaths occur in low- and middle-income countries. Read more

PhD Studentship in “Multi-scale mathematical models to predict prostate cancer progression and treatment response.” (2024)

PhD studentship in the Groups of “Mathematics Applied to Biology” and “Numerical Analysis and Scientific Computing” at the University of Sussex (UK), with the collaboration of the “Group of Numerical Methods in Engineering” at the University of A Coruña (Spain). Read more

SLS 3: Investigating the anti-inflammatory effects of artemisinin compounds on macrophages under systemic inflammatory conditions

Artemisinin compounds are safe and effective antimalarials. Recent evidence in our lab has shown these compounds also exert a potent anti-inflammatory effect by inhibiting neutrophil migration and the release of cytokines, chemokines and neutrophil extracellular traps. Read more

Diagnostics for FMF patients and carrier survival in pandemics

Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more

Development of miRNAs as a new therapeutic tool in the treatment of cardiovascular diseases

Ischemic heart diseases and their pathological consequences belong to the leading causes of death worldwide. In the acute treatment of myocardial ischemia one of the most important tasks is the restoration of the tissue perfusion. Read more

Short and long-term genetic and behavioural consequences of traumatic brain injury in fruit flies

General background . How many fingers am I holding up? What day of the week is it? Follow my finger? These three questions are designed to test your sensory, memory and motor neural abilities following an accident; all three systems are affected by a severe deceleration of your brain. Read more

The Role of Reactive Sulfur Species in the Ageing Heart

Second Supervisor. Prof Melanie Madhani, University of Birmingham. Background . Ageing is a natural and complex biological process that involves the gradual deterioration of cells, tissues, and organ systems over time, thus leading to an increased susceptibility to diseases and mortality. Read more

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Fully Funded PhD Scholarship in Centrosome Biology

Applications are invited from suitably qualified candidates for a 4-year, full-time funded PhD scholarship(s) starting in June-October 2024 affiliated to the School of Biological and Chemical Sciences at the University of Galway. Read more

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