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elisa PhD Projects, Programs & Scholarships

We have 44 elisa PhD Projects, Programs & Scholarships

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  Regulation of intestinal immune responses to commensal bacteria by innate lymphoid cells
  Dr M Hepworth, Prof K Else
Applications accepted all year round

Funding Type

PhD Type

Commensal bacteria present in the gastrointestinal tract provide beneficial roles for the host, such as supporting nutrient metabolism.
  The effects of Interleukin-1 primed mesenchymal stem cells on hypoxic-ischemic brain damage
  Dr E Pinteaux, Prof S Allan
Applications accepted all year round

Funding Type

PhD Type

Hypoxic-ischemic brain damage is one of the main causes of death and neurological disability after stroke worldwide.
  Developing a virus-like particle (VLP) Polio vaccine
  Dr G Mulley
Applications accepted all year round

Funding Type

PhD Type

Rationale. Poliovirus is a non-enveloped RNA virus, spread via the faecal-oral route, that causes the infectious disease Poliomyelitis (Polio).
  Development of novel macrophage high-throughput cell-based phenotypic assay for drug screening
  Research Group: Biomedical Research Group
  Dr G Pirianov, Prof S Cellek
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Gastrointestinal modulation using omega-3 and probiotic strategies and its effect on cardio-metabolic health in obese and non-obese populations
  Research Group: Cambridge Centre for Sport and Exercise Sciences
  Dr J Roberts, Dr L Smith
Applications accepted all year round

Funding Type

PhD Type

Research Group. Cambridge Centre for Sport and Exercise Sciences - https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/cambridge-centre-for-sport-and-exercise-sciences.
  Investigating the anti-cancer effect of hop β -acid Lupulone and its synthetic derivatives on breast cancer cells
  Research Group: Biomedical Research Group
  Dr G Pirianov
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Investigating the potential of novel mimetic molecules (Toll-like receptor 4 antagonists) to modulate the microphage polarisation
  Research Group: Biomedical Research Group
  Dr G Pirianov, Dr N Pugh
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Regulation of mineralisation in atherosclerotic lesions
  Research Group: Biomedical Research Group
  Dr J Bird, Dr G Pirianov
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Regulation of the tissue degradation in osteoarthritis
  Research Group: Biomedical Research Group
  Dr J Bird, Dr P Coussons, Dr F Savage
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Regulation of trans-intestinal cholesterol efflux by pattern-recognition receptor signalling in enterocytes
  Research Group: Biomedical Research Group
  Dr C Erridge, Dr J Bird
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Nanoparticles in drug delivery
  Dr G Stenbeck, Dr U Kishore
Applications accepted all year round

Funding Type

PhD Type

Nanoparticles (NPs) are materials with overall dimensions in the nano scale range (5nm-100nm). Due to their unique physicochemical properties, they have found a wide range of applications and are currently explored as drug and gene delivery vehicles.
  Antibody-drug conjugates (ADCs) for the treatment of solid tumours
  Dr S Karagiannis, Prof J Downward
Application Deadline: 29 November 2019

Funding Type

PhD Type

An Antibody-Drug Conjugate (ADC) comprises an antibody targeted toward a tumour cell surface antigen, coupled through a chemical linker to a highly-cytotoxic drug.
  Exercise and nutritional status on metabolic factors, hormonal responses and inflammation in women
  Dr J Allgrove
Applications accepted all year round

Funding Type

PhD Type

Obesity is a major risk factor for chronic diseases such as type 2 diabetes, adverse cardiovascular events and metabolic syndrome-related disorders.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  Oral delivery of insulin for diabetes therapy: Development and evaluation of insulin loaded polymer/lipid based carrier systems
  Dr A Vangala
Applications accepted all year round

Funding Type

PhD Type

Diabetes is a chronic metabolic disorder that affects nearly 500 million people worldwide. Its hallmark feature, hyperglycaemia is caused due to insulin deficiency and/or resistance.
  Enjoyable interventions to improve inflammatory status, glycaemic control and energy balance – metabolic and affective responses to body temperature elevations
  Dr CA Leicht, Dr L James
Application Deadline: 30 November 2019

Funding Type

PhD Type

The aim of this PhD project is to assess the use of increasing body temperature to benefit health - the overarching aim is to inform health interventions based on thermal therapy.
  MRC DiMeN Doctoral Training Partnership: Stopping bone metastasis in its tracks: Targeting glycan sugar groups to improve early diagnosis and prevent/inhibit the spread of prostate cancer to bone
  Dr J Munkley, Dr N Wang
Application Deadline: 6 January 2020

Funding Type

PhD Type

Prostate cancer is the most commonly diagnosed malignancy in men, claiming over 350,000 lives worldwide annually. More than 80% of men with advanced prostate cancer will develop painful and incurable bone metastasis.
  Antibiotics; good gone bad? Impact on liver immunity and susceptibility to injury (BERAZAQ20DTP2)
  Dr N Beraza
Application Deadline: 25 November 2019

Funding Type

PhD Type

The use of antibiotics has saved millions of lives. Worryingly, antibiotics modify dramatically the composition of our intestinal microbiome and can lead to the permanent loss of certain species.
  Metabolism as a regulator of stressed haematopoiesis; implications for liver function during ageing. (BERAZAQ20DTP1)
  Dr N Beraza
Application Deadline: 25 November 2019

Funding Type

PhD Type

During homeostasis, our body’s immunological defence relies on the expansion and differentiation of haematopoietic stem cells (HSC).
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  Environmental control of dendritic cell activation and function during pulmonary type 2 inflammation
  Prof A MacDonald, Prof J Allen
Applications accepted all year round

Funding Type

PhD Type

Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as well as being responsible for widespread suffering in allergies.
  How do phosphodiesterases contribute to the pathophysiology of heart failure?
  Prof A Trafford, Dr K Dibb
Applications accepted all year round

Funding Type

PhD Type

Heart failure (HF) remains a major cause of death with worse 5-year survival than all forms of cancer combined. This project seeks to understand the mechanisms that underlie two important contributing factors to death in HF patients; i) contractile failure and, ii) the increased propensity for arrhythmias.
  The impact of zinc deficiency on Alzheimer’s disease
  Dr C Lawrence, Prof D Brough
Applications accepted all year round

Funding Type

PhD Type

In addition to memory problems, people with Alzheimer’s disease (AD) also experience ‘non-memory’ behavioural symptoms including depression, anxiety, and agitation.
  The respiratory metagenome during exacerbations of asthma
  Prof N Papadopoulos, Prof D Robertson, Dr S Megremis
Applications accepted all year round

Funding Type

PhD Type

Asthma is an international pandemic, with 10% or more of the global population having experience asthma symptoms some time in life.
  Male-driven sex allocation: adaptive adjustments in sperm sex ratios.
  Dr R Firman
Application Deadline: 20 February 2020

Funding Type

PhD Type

The ability of males to adjust offspring sex ratios has traditionally been dismissed on the assumption that their contribution is genetically determined during meiosis and therefore not under adaptive control.
  GW4 BioMed MRC DTP PhD studentship: Novel Diagnostics for Stress and Neuroendocrine Disorders
  Dr N Reis
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Targeting the Role of Myeloid Steroid Metabolism in Chronic Inflammation
  Dr R Hardy, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.
  Vitamin D and immunometabolism
  Prof M Hewison, Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Vitamin D has potent anti-inflammatory and antibacterial immune effects.
  Immune cell-mediated steroidogenesis in regulating cancer immunity
  Dr B Mahata, Prof K Okkenhaug
Application Deadline: 1 January 2020

Funding Type

PhD Type

Steroidogenesis is a process by which cholesterol is converted into steroid hormones in the adrenal glands, gonads and placenta. The endocrine role of systemic steroid hormones in regulating immune cell function is well-established.
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