We have 42 epigenetic PhD Projects, Programmes & Scholarships

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epigenetic PhD Projects, Programmes & Scholarships

We have 42 epigenetic PhD Projects, Programmes & Scholarships

Epigenetic ageing and calorie restriction in an insect model system

University of Leicester Department of Genetics and Genome Biology

This project will help establish an insect model for epigenetic ageing, by analysing the effects of calorie restriction on chronological and epigenetic aging in an important insect model, Nasonia vitripennis, extending our discovery of an epigenetic clock in Nasonia. . Read more

Supervisors: Prof E Mallon, Dr K Chen

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Epigenetic profiling of cereal fungal invaders. (SAUNDERS_J24DTP1)

John Innes Centre Graduate Programme

Wheat blast and rusts are fungal diseases that severely damage cereal production worldwide. During infection, these fungi secrete proteins into wheat plants to reprogramme host plant circuitry, supporting their own growth and development. Read more

Supervisor: Dr D Saunders

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Cancer Epigenetics project

University of Otago Department of Pathology

Broad Project Summary: Cancer is a leading cause of morbidity and mortality worldwide. Epigenetic changes are now recognised as a hallmark feature of cancer, but our understanding of factors that are responsible for tumour spread still remains limited. Read more

Supervisor: Assoc Prof A Chatterjee

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

Unraveling the Impact of Epigenetic and Microenvironmental Factors on Breast Cancer Development and Progression

University of York York Biomedical Research Institute

Breast cancer is a complex disease with multifaceted aetiology, and understanding the processes that regulate disease development and progression is crucial for improving diagnostics and treatment strategies. Read more

Supervisors: Dr AN Holding, Dr W Brackenbury

Year round applications PhD Research Project Self-Funded PhD Students Only

Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks

Nottingham Trent University School of Science & Technology

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children. Read more

Supervisor: Dr A Antonysunil

Year round applications PhD Research Project Self-Funded PhD Students Only

Early life environment changes how organisms age.

University of Leicester Department of Genetics and Genome Biology

This project will help understand why organisms age differently by establishing the effect of early life environments on epigenetic ageing in the model insect, Nasonia vitripennis. Read more

Supervisor: Prof E Mallon

Year round applications PhD Research Project Self-Funded PhD Students Only

Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

University of Nottingham School of Medicine

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more

Supervisors: Prof K Gaston, Dr S Jayaraman

Year round applications PhD Research Project Self-Funded PhD Students Only

Unravelling the role of G-quadruplex structures in brain ageing and neurodegeneration

Imperial College London Institute of Chemical Biology

The increasing incidence of neurodegenerative disorders is posing a significant threat to the NHS and public health services world-wide. Read more

Supervisors: Dr M Di Antonio, Dr R Nativio, Dr S Galli

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Cellular mechanisms of equal chromosome segregation and genome stability

University of Southampton School of Biological Sciences

The PhD project will investigate how chromosomes segregate equally in each cell division through epigenetic regulation of the centromere, and how cells respond in stress conditions to maintain genome instability. Read more

Supervisor: Assoc Prof W.Y.K.Y. Yuen

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier

Year round applications PhD Research Project Self-Funded PhD Students Only

Fully funded PhD studentship: Towards rapid and early cancer diagnostics at the point of care using machine learning assisted vibrational spectroscopy

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team. Prof. Senthil Murugan Ganapathy. Project description. Cancer continues to be one of the most prevalent diseases worldwide. Read more

Supervisor: Prof S Ganapathy

Year round applications PhD Research Project Competition Funded PhD Project (European/UK Students Only)

Manipulation of neuroimmune responses and behaviour by infectious agents

University of Leeds Faculty of Biological Sciences

This project is available exclusively to self-funded students who wish to commence study for a PhD in the academic year 2023/24. The project focuses on how infectious agents modify the individuals that they infect and how neuroimmune responses to infection moderate behaviour changes in warm-blooded animals and humans. Read more

Supervisors: Dr G Mcconkey, Dr S Clapcote

Year round applications PhD Research Project Self-Funded PhD Students Only

PhD candidate - Origin of Obesity and Metabolic Disorders in Childhood (f/m/x)

Helmholtz Zentrum Munich Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG)

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. Read more

Supervisor: Prof S Körner

22 March 2025 PhD Research Project Funded PhD Project (Students Worldwide)

Developmental consequences of heat stress during early mammalian embryogenesis

University of Nottingham School of Biosciences

Epidemiological evidence in humans indicates that acute heat exposure around the time of mating results in pregnancy loss, with potential long-term consequences for offspring health and wellbeing; although these latter adverse effects are poorly understood. Read more

Supervisors: Prof K D Sinclair, Dr R Alberio, Prof D Gardner

10 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Self funded PhD in Biology: Structure and function of CIZ1

University of York Department of Biology

Lead supervisor: Prof Dawn Coverley. Co-supervisors: Prof Fred Antson. The student will be registered with the Department of Biology. Read more

Supervisors: Prof D Coverley, Prof F Antson

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

The 46th chromosome in XX female mammals, the second X, has to be switched off. That way females equalize gene dosage of X-linked genes with XY males. Read more

Supervisors: Dr Y Markaki, Prof J Schwabe, Dr JH Hodgkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

Identifying causal pathways to disease using DNA methylation derived scores.

University of Bristol Bristol Medical School

Rationale. DNA methylation is an epigenetic biomarker that has been shown to reflect lifestyle and biological factors (smoking, alcohol use, chronological age). Read more

Supervisors: Dr J Min, Prof C Relton, Prof J MIll, Dr E Hannon, Dr G Hemani, Prof T Gaunt, Dr B Heijmans, Dr J Bell

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisors: Prof D Panne, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

PHD POSITION IN STATISTICAL GENOMICS/GENETIC EPIDEMIOLOGY

Max Planck Institute for Psycholinguistics Language & Genetics

The Max Planck Institute (MPI) for Psycholinguistics, Nijmegen, the Netherlands, is offering a PhD position in Statistical Genomics/Genetic Epidemiology within the population genetics of human communication group, led by Dr Beate St Pourcain and embedded within the Language & Genetics Department at the MPI. Read more

Supervisor: Dr B St Pourcain

15 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

University of Bristol School of Biochemistry

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more

Supervisor: Prof M D Szczelkun

Year round applications PhD Research Project Self-Funded PhD Students Only

Discovery of cancer antigens that are epigenetically-regulated as biomarkers and vaccine candidates

Queen Mary University of London Blizard Institute

We are seeking a graduate who is passionate about contributing to cancer research and who has a background in immunology or epigenetics and a degree at least at the upper second-class honours level. Read more

Supervisors: Dr H.R Rowe, Prof G.K Kassiotis

5 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Genetics of flowering shoot temperature responses in plants

Durham University Department of Biosciences

The shape of plants is shaped by both genetics and environment; changes in response to temperature can be the most dramatic of all. Read more

Supervisor: Dr J Hepworth

3 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Eliminating Harmful Cells to Maintain Homeostatis and Prevent Tumorigenesis

Cardiff University Cardiff School of Biosciences

Hamaratoglu Lab studies cell-cell signalling in development, homeostasis and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. Read more

Supervisors: Dr F Hamaratoglu, Dr C Hogan

8 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Self funded MSc by Research or PhD in Biology: The oncogenic mechanism and potential of the emergent retrovirus ALV-K in global poultry

University of York Department of Biology

Lead supervisor: Dr Andrew Mason. The student will be registered with the Department of Biology. Background. Avian Leukosis Viruses (ALV) are oncogenic retroviruses which cause blood cancers in chickens, impacting commercial productivity and animal welfare. Read more

Supervisor: Dr A Mason

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Molecular mechanisms of the increase in maximal aerobic capacity (VO2max) with regular exercise

University of Stirling Faculty of Health Sciences and Sport

Research Group: PENRG - Physiology Exercise and Nutrition Research Group

Performing regular exercise is crucial for good health and wellbeing, whereas failing to perform sufficient exercise increases the risk of diseases such as cardiovascular disease, type 2 diabetes, cancer, etc. Read more

Supervisors: Dr N Vollaard, Dr ECR Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

PI3K-Akt expression in dysplastic oral lesions and implications for recurrence and malignant transformation

University of Dundee Dental School

There are around 12,400 new head and neck cancer cases in the UK every year, that's 34 every day (2016-2018) with 4,143 deaths each year. Read more

Supervisors: Prof M Macluskey, Dr I Ellis, Dr M Islam, Dr S. J. Jones

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Biological pathways supporting the formation and function of chromatin (Scholarship)

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Every cell in our body contains the same DNA yet each cell expresses a different set of genes. These changes in gene expression are heavily influenced by histone proteins, their role in packaging DNA into chromatin and the “epigenetic” information they carry. Read more

Supervisor: Dr CM Hammond

Year round applications PhD Research Project Self-Funded PhD Students Only

Structural insights into genome control by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisor: Prof D Panne

Year round applications PhD Research Project Self-Funded PhD Students Only

Making sense of antigenic variation in trypanosomes: a nuclear factory with a switching problem

University of York York Biomedical Research Institute

Trypanosomes are master of disguise. African trypanosomes cause huge morbidity and economic burden amongst some of the world’s poorest populations. Read more

Supervisors: Dr J Faria, Dr R McCulloch

Year round applications PhD Research Project Self-Funded PhD Students Only

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