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epithelial PhD Projects, Programs & Scholarships

We have 86 epithelial PhD Projects, Programs & Scholarships

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  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
  MRC DiMeN Doctoral Training Partnership: Understanding dysregulated repair in lung disease through precise laser injury and quantitative analysis of live cell behaviours in a human airway epithelial model
  Dr C Ward, Dr R Tetley, Dr J Garnett
Application Deadline: 6 January 2020

Funding Type

PhD Type

Noncommunicable diseases, including chronic respiratory diseases, are responsible for 63% [36 million] of all deaths worldwide, making improved understanding and research an international priority.
  Understanding how the bitter taste receptor, T2R38, regulates the intestinal epithelium - a study from microbiota to the intestinal epithelium
  Research Group: Biomedical Research Group
  Dr H Chichger
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  The Cellular Origin of Human Papillomavirus Associated Neoplasia
  Dr J Doorbar
Application Deadline: 1 January 2020

Funding Type

PhD Type

Human Papillomaviruses (HPV) cause widespread asymptomatic infections in the general population, in addition to a range of cancers which occur at number of well defined epithelial sites.
  Investigating the biomedical implication of microplastic accumulation on human epithelial barriers and associated effects on immune function, fibrosis and premature tissue ageing
  Research Group: Biomedical Research Group
  Dr P Dyer, Dr D Green, Prof S Cellek
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  How does epithelial tissue organization modulate pluripotent stem cell identity and fate?
  Dr M Shahbazi
Application Deadline: 3 December 2019

Funding Type

PhD Type

During embryogenesis pluripotent stem cells give rise to all the cell types present in the organism. How pluripotent cells decide their fate is a fundamental question in development and regeneration.
  Neutrophils, TLR4 and Streptococcus pneumoniae and RSV co-infection of airway epithelial cells
  Dr C Smith
Application Deadline: 29 November 2019

Funding Type

PhD Type

A 3-year PhD Studentship is available within the Respiratory, Critical Care and Anaesthesia Section, UCL Great Ormond Street Institute of Child Health under the supervision of Dr Claire Smith, and Professor Rosalind Smyth to start on 1st September 2020, or earlier.
  A human ’mini-gut-on-a-chip’ to study microbial-epithelial cell interactions (SAEEDU20DTP)
  Dr A Saeed, Dr M R Williams
Application Deadline: 25 November 2019

Funding Type

PhD Type

Human organoids are 3D fragments of adult tissues and ideally conserve all of the (stem) cell types and recapitulate all of the (patho)physiological processes associated with human health and disease.
  Kidneys in a dish: epithelial polarity and tube formation in human renal organoids
  Dr K Roeper
Application Deadline: 3 December 2019

Funding Type

PhD Type

Epithelia constitute one of the major tissue types in all animals and form the basic building blocks of tubular organs in both vertebrates and invertebrates.
  EASTBIO Discovering regulatory principles for the thymic epithelial progenitor/stem cell state.
  Research Group: Institute of Stem Cell Research
  Prof C Blackburn, Dr R Grima
Application Deadline: 5 January 2020

Funding Type

PhD Type

T cells are vital regulators and effectors of the adaptive immune system.
  Characterisation of the genotype and phenotype of epithelial cells invaded by the periodontal pathogen Porphyromonas gingivalis.
  Dr S Whawell, Dr G Stafford
Applications accepted all year round

Funding Type

PhD Type

The presence of the Gram negative anaerobe Porphyromonas gingivalis is consistently associated with the more severe forms of periodontal disease and its ability to invade host epithelial cells is thought to be important in the pathogenesis of the disease.
  Application of machine learning to establish epigenetic regulators in breast and bladder epithelial tissue
  Dr AN Holding, Prof J Southgate
Application Deadline: 5 January 2020

Funding Type

PhD Type

Epigenetics. modifications to DNA and histones that change the expression. of genes but do not alter the code of the genes, are critical to the.
  A potential role for Epithelial Mesenchymal Trans differentiation (EMT) in the Pathogenesis of Periodontal Disease
  Prof PR Cooper, Dr M Milward
Applications accepted all year round

Funding Type

PhD Type

Periodontitis is a ubiquitous chronic inflammatory disease that destroys the supporting structures of teeth; the most common form is chronic periodontitis which if untreated results in the breakdown of soft tissues and bone, ultimately leading to tooth loss.
  Scaffolds for supporting epithelial cells
  Research Group: Chemistry and Biosciences
  Prof S Rimmer, Dr W Martin
Applications accepted all year round

Funding Type

PhD Type

Tissue engineering requires the availability of polymer materials that can support cells and the development of tissues. Many synthetic materials are tough, easily fabricated and non-toxic.
  EASTBIO: Emergence of functional polarity in a tubular epithelium
  Dr B Denholm, Prof A Jarman
Application Deadline: 5 January 2020

Funding Type

PhD Type

Epithelial tubes are the conduit through which life-sustaining gases, nutrients and fluids are transported. But they do more than simply convey material to and fro – they carry out vital roles in modifying the material passing through.
  The role of cell adhesion proteins in healthy and cancerous epithelial cells
  Dr C Ballestrem, Prof D R Garrod
Applications accepted all year round

Funding Type

PhD Type

The cells’ ability to properly communicate with its environment is fundamental for the healthy development of individual organisms.
  The role of pore-forming bacterial proteins in pneumonia and meningitis
  Prof T J Mitchell, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

The bacterium Streptococcus pneumoniae (the pneumococcus) is carried in the nasopharynx of most children and some adults without causing disease.
  The role of oesophageal submucosal glands in epithelial homeostasis and the development of Barrett’s oesophagus
  Research Group: Cancer Biology & Surgical Oncology Laboratory
  Prof W. Phillips, Dr N. Clemons
Applications accepted all year round

Funding Type

PhD Type

Barrett’s oesophagus, the premalignant precursor of oesophageal adenocarcinoma, is a metaplastic condition where the normal stratified squamous epithelium that lines the oesophagus is replaced by an intestinal-like columnar epithelium.
  Systematisation of epithelial architecture using mathematical morphology and graph theory
  Prof G Landini
Applications accepted all year round

Funding Type

PhD Type

Quantitative Pathology investigates problems in pathology using innovative, analytical methods to collect reliable, quantifiable and reproducible markers of disease.
  Development of “FXR-targeted” Nutraceuticals for Treatment of Intestinal Diseases
  Prof S Keely, Dr S Das
Application Deadline: 2 December 2019

Funding Type

PhD Type

The incidence of intestinal diseases, such as colorectal cancer (CRC) and inflammatory bowel disease (IBD), is significantly higher in Western societies than elsewhere in the world.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  The Genomics of Hereditary Prostate Cancer
  Prof R Bristow
Application Deadline: 3 January 2020

Funding Type

PhD Type

This 4 year PhD studentship offered in Professor Rob Bristow’s research group is based at the Cancer Research UK Manchester Institute, Manchester Cancer Research Centre, Oglesby Cancer Research Building, Manchester.
  Development of a novel 3D gut-microbiota model for the assessment of absorption and metabolism of health supplements and therapeutic drugs
  Dr P Ragazzon
Application Deadline: 10 December 2019

Funding Type

PhD Type

The gut epithelium is a complex setting of intestinal cells and epithelial cells filled with transporters, enzymes and channels; these cells are then populated by bacteria (microbiota) that help with the metabolism of nutrients and transport into the blood stream.
  Oral delivery of insulin for diabetes therapy: Development and evaluation of insulin loaded polymer/lipid based carrier systems
  Dr A Vangala
Applications accepted all year round

Funding Type

PhD Type

Diabetes is a chronic metabolic disorder that affects nearly 500 million people worldwide. Its hallmark feature, hyperglycaemia is caused due to insulin deficiency and/or resistance.
  Optimisation and Preclinical Evaluation of Targeted Nanoformulations of Anti‐TNF‐α Therapeutics for the Treatment of Inflammatory Bowel Disease (IBD)
  Dr Z Ramtoola, Dr B Kirby
Application Deadline: 2 December 2019

Funding Type

PhD Type

Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition that affects the gastrointestinal tract (GIT) of the patient and comprises of Crohn’s disease (CD) and ulcerative colitis (UC).
  (BBSRC DTP) From mucin biochemistry to pulmonary immunity: How do mucins promote antimicrobial lung defences?
  Prof E Bignell, Prof D Thornton, Dr A Horsley
Application Deadline: 31 January 2020

Funding Type

PhD Type

Respiratory mucus plays multiple essential roles in mammalian lung function, from hydrating the epithelium and supporting gaseous exchange, to expelling inhaled particles and microbes and providing a conduit for innate and adaptive immune signaling.
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  Developing a tissue engineered/polyurethane blood vessel using bioengineering techniques
  Research Group: Chemistry and Biosciences
  Prof S Rimmer, Prof A M Graham, Dr K Riches-Suman
Applications accepted all year round

Funding Type

PhD Type

Vein graft failure is a significant issue in cardiovascular disease patients, with restenosis caused by alterations in flow patterns leading to remodelling and disease progression.
  How does the protein LicB underpin infection by opportunistic bacteria?
  Dr P Curnow
Application Deadline: 25 November 2019

Funding Type

PhD Type

The human body is colonized by trillions of bacteria. These are generally harmless but can become a serious threat to human health.
  Live-imaging and genetic approaches to explore cross-talk between tissue damage, immune dysfunction and infection within novel animal models of cystic fibrosis
  Dr H Weavers, Prof E Mahenthiralingam, Dr D N Sheppard
Application Deadline: 25 November 2019

Funding Type

PhD Type

Cystic fibrosis (CF) is a genetic disorder driven by mutations in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene.
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