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We have 10 fetal PhD Projects, Programmes & Scholarships

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fetal PhD Projects, Programmes & Scholarships

We have 10 fetal PhD Projects, Programmes & Scholarships

Role of mechanical signals in a 3D human model of alveolar differentiation

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Advancing translational cell therapy for Hirschsprung disease

Clinical disorders characterised by neuronal loss or dysfunction in the gastrointestinal tract remain some of the most challenging to manage, with considerable morbidity and mortality and very limited treatments. Read more

The effect of low protein diet on the development of the neuromuscular system

Age-related sarcopenia is characterised by reduction in the number of myofibres and motor neurons and an additional weakening of the remaining fibres, causing reduction in muscle mass and function. Read more

Computational modelling to understand the key drivers of placental evolution

Supervisory Team. Bram Sengers (SoE), Rohan Lewis (Medicine). Project description. This project will use computational modelling in combination with 3D multiscale multimodal imaging to improve our understanding of placental evolution, in close collaboration between Engineering and Medicine. Read more
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