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genes PhD Projects, Programmes & Scholarships

We have 219 genes PhD Projects, Programmes & Scholarships

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Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more
 Supervisors: Dr S Shnyder, Prof S El-Khamisy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biological rhythms and the dopamine system in cognitive dysfunction

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more
 Supervisors: Dr S McLean, Dr G Helfer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying Mechanisms of Tyrosine Kinase Inhibitor Resistance in Breast/Cervical Cancer (with emphasis on FGFR)

Kingston University Faculty of Health, Science, Social Care and Education
FGF signalling is implicated in cancer (e.g., breast and cervical cancer) susceptibility and progression, suggesting that this powerful developmental pathway is co-opted by cancer cells. Read more
 Supervisor: Dr A Chioni
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Structural insights into genome control by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisor: Prof D Panne
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genome mining of novel antimicrobial natural products

Aberdeen University School of Natural and Computing Sciences
These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more
 Supervisor: Dr H Deng
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: The Generation Gap – understanding tissue communication during grain development

University of Dundee School of Life Sciences
Cereal grain provides more calories than any other source to our diet, making grain production vital to food security. We study grain development in barley, a globally important cereal, and a powerful genetic model system. Read more
 Supervisor: Dr S McKim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: Using hypomethylating agents to prevent respiratory infections in older adults

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr c Quin, Prof H Wilson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Unravelling Alpha-Arrestins: A Promising Strategy to Conquer Candida Infections and Multidrug Resistance

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr T Kubota, Dr R Hatakeyama
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: Cell based assays for the detection of environmental toxins

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr A Kolb, Dr S Gratz
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The world is getting hotter and drier due to climate change, and the human population is growing rapidly. Furthermore, it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more
 Supervisors: Dr J Hartwell, Dr P Walley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

Queen’s University Belfast School of Pharmacy
One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more
 Supervisor: Dr N Buckley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology
More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more
 Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more
 Supervisor: Dr K Tanaka
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unlocking the potential of plant cellulose for the production of new materials and chemicals

The University of Manchester Faculty of Biology, Medicine and Health
Plant biomass, in the form of plant cell walls are the only renewable resource sufficiently abundant to make a meaningful contribution to decreasing CO. Read more
 Supervisors: Prof S Turner, Dr J Pittman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A deep-learning approach to genomic regulation of tissue-specific alternative splicing

The University of Manchester Faculty of Biology, Medicine and Health
Each human gene is a blueprint for multiple distinct RNA transcripts that can be produced in differing quantities based on the localisation of the transcribing… Read more
 Supervisors: Dr JE Eales, Prof T Papamarkou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of dietary fructose in the development of early-onset colorectal cancer

University of Bristol Bristol Medical School
Project Background. This project will investigate the role of fructose in the development of early-onset colorectal cancer (EOCRC) in adults <50 years. Read more
 Supervisors: Dr E Vincent, Dr A Chambers, Dr R Richmond, Dr NM Murphy
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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The analysis of HIF function in DNA repair and genome stability

University of Sheffield School of Biosciences
DNA damage is a factor that underlies many human diseases. Such damage results in mutations, and if such genetic alterations occur in tumour suppressor or proto-oncogenes it can lead to cancer. Read more
 Supervisors: Dr F Van Eeden, Prof S El-Khamisy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Retrotransposons in immunity

UNSW Sydney School of Biotechnology and Biomolecular Sciences
Only about 1-2% of our genome is made up of protein coding genes, the rest is non-coding and at least half of that is made up of repetitive DNA sequences known as transposable elements (TEs). Read more
 Supervisor: Prof C King
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Skeletal Muscle Organoid Models for Genetic Mitochondrial Disease (ref: SF22/HLS/APP/Johnson)

Northumbria University Faculty of Health and Life Sciences
Genetic mitochondrial diseases are both clinically and genetically heterogeneous. Read more
 Supervisor: Dr S Johnson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

University of Nottingham School of Medicine
It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more
 Supervisors: Prof K Gaston, Dr S Jayaraman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Circadian mechanisms in psoriasis: therapeutic opportunities

The University of Manchester Faculty of Biology, Medicine and Health
Hallmark features of psoriasis symptoms vary through time, suggesting an important role for circadian circuits in driving disease expression, and offering the potential of chronotherapy. Read more
 Supervisors: Dr H Young, Dr I Iqbal, Prof D Ray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of calcium signalling in regulating of tumour cell behaviour

University of Nottingham School of Life Sciences
Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more
 Supervisors: Dr M Georgiou, Dr IM Maiellaro
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

University of Leeds Faculty of Medicine and Health
Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more
 Supervisor: Prof U Klein
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

University of Leeds Faculty of Medicine and Health
Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more
 Supervisors: Prof M Wilcox, Prof A O'Neill, Dr J Freeman, Dr I Moura
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
 Supervisor: Prof T Gaunt
 20 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Embodiment of Robotic tail - Can we walk like a T-Rex?

University of Reading Department of Biomedical Engineering
Project Overview. Individuals skilled in using tools for sports, arts, and culinary activities might experience notable alterations in their bodily self-perception. Read more
 Supervisors: Dr Y Hayashi, Prof W Harwin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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DNA-bending Proteins for Nanotech

University of York School of Physics, Engineering and Technology
DNA is the molecule that nature uses as genetic material and it rarely exists in a relaxed state inside cells. Read more
 Supervisor: Dr A Noy
 31 October 2024  PhD Research Project  Self-Funded PhD Students Only
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Investigating ubiquitin signalling in the radiotherapy response of glioblastoma

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: Edinburgh Cancer Research Centre
Students will be registered for their degree at either the University of Glasgow or Edinburgh, depending on the project they apply for. Read more
 Supervisor: Dr VD D’Angiolella
 20 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Integrative genomics prioritisation of drug targets

University of Bristol Bristol Medical School
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
 Supervisor: Prof T Gaunt
 20 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more
 Supervisors: Dr K Tanaka , Dr R Mahen
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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