We have 220 genes PhD Projects, Programmes & Scholarships

The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more

Supervisors: Dr M Lagator, Dr CI Igler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing novel treatments for invasive fungal infections

University of Strathclyde Department of Pure and Applied Chemistry

Invasive Fungal Infections. Invasive fungal infections, such as those caused by the fungi Candida, are an increasing global public health concern. Read more

Supervisor: Dr FS Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of high provitamin A (beta carotene) fruits and vegetables

Royal Holloway, University of London School of Biological Sciences

Vitamin A deficiency (VAD) remains a global health problem. It is the leading cause of preventable blindness in young children, can compromise immune function and exacerbates childhood diseases. Read more

Supervisors: Prof P Fraser, Dr LP Perez , Dr G Enfissi

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Stochastic modelling and inference for live-cell gene expression time-series data to unravel the mechanisms of stem cell differentiation

University of St Andrews School of Mathematics and Statistics

Research Group: Division of Statistics

This project will develop statistical methodology for noisy time-series data and stochastic computational models to analyse live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more

Supervisor: Dr G Minas

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Molecular Mechanisms of Resolution of Inflammation

University of Birmingham Institute of Inflammation and Ageing

We are seeking talented, motivated students to join the research group led by Professor Andy Clark (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/clark-andy.aspx), a member of the University of Birmingham’s Rheumatology Research Group (https://www.birmingham.ac.uk/research/inflammation-ageing/research/rheumatology-research-group/index.aspx). Read more

Supervisor: Prof A Clark

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic basis of immunological overlap between inflammatory diseases

The University of Manchester Faculty of Biology, Medicine and Health

Genetic studies have identified numerous variants within the human genome associated with susceptibility to common complex inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). Read more

Supervisors: Mr P Martin, Prof S Eyre, Prof A Morris

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School

Rationale. Mendelian Randomization (MR) is a genetic epidemiology method which utilises variants sourced from genome-wide association studies (GWAS) to assess causality between risk/protective factors and disease outcomes in a manner less biased to observational studies(1). Read more

Supervisors: Prof T Gaunt, Dr M Sobczyk

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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The genetics of human scarring – cross-cutting approaches to the understanding of human wound repair.

University of Bristol Bristol Medical School

Rationale. Repair of adult tissues involves a complex interplay of several key cell lineages and inevitably leads to formation of a fibrotic collagenous scar. Read more

Supervisors: Prof N Timpson, Prof P Martin

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Harnessing genetics of DNA methylation to elucidate molecular mechanisms underlying human phenotypes.

University of Bristol Bristol Medical School

Rationale. GWAS studies have discovered many genetic associations for traits and diseases, but it has been difficult to elucidate the functional consequences of these variants. Read more

Supervisors: Dr J Min, Prof C Relton, Prof J MIll, Dr E Hannon, Dr G Hemani, Prof T Gaunt, Dr B Heijmans, Dr J Bell

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Establishing and orienting causal relationships between sleep characteristics and reproductive function

University of Bristol Bristol Medical School

Rationale. A large body of literature from animal studies has highlighted the role of core clock genes in relation to reproductive function [1]. Read more

Supervisors: Dr R Richmond, Dr G Sharp, Prof D Lawlor

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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The use of life course epidemiology to support the experimental characterisation of genetic variation

University of Bristol Bristol Medical School

Project Background. There has been a rapid expansion in the generation of genetic sequence data over the last decade. Understanding the potential relevance of genetic mutations to human health remains challenging. Read more

Supervisors: Prof N Timpson, Dr L Corbin, Dr BL Lam

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression and tumorigenesis

Masaryk University Faculty of Medicine

Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development. Read more

Supervisor: Dr D Blažek

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Understanding Spinal Cord Regeneration: The role of dynamic gene expression

The University of Manchester Faculty of Biology, Medicine and Health

Spinal cord injury(SCI) paralysis is a devastating disease that affects at least 2500 people per year in the UK. It carries substantial individual and societal costs with most SCI sufferers experiencing chronic pain. Read more

Supervisors: Dr X Soto Rodriguez, Dr K Dorey, Dr Cerys Manning

Year round applications PhD Research Project Self-Funded PhD Students Only

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Functional Mechanisms of Genetic Risk Factors for Immune-Related Disease

King’s College London School of Medicine

Who are we?. Read more

Supervisor: Prof T Vyse

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

University of Portsmouth School of Pharmacy and Biomedical Sciences

Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more

Supervisors: Dr R Hadianamrei, Dr S Hafizi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Ethnic-specific markers and mediators of metabolism and disease risk

University of Leeds Faculty of Environment

Globally, cancer, diabetes, and cardiovascular are the leading cause of death. These diseases are linked to a person's age, ethnicity, culture, genetics, and lifestyle habits, such as diet and exercise. . Read more

Supervisor: Dr M Zulyniak

Year round applications PhD Research Project Self-Funded PhD Students Only

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Why do cancers cells re-express meiotic SYCP1 protein?

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The aim of meiosis is to generate gametes by recombining the chromosomes and reducing the genome from diploid to haploid. However, in mitosis haploid genome and recombination have catastrophic, oncogenic outcomes. Read more

Supervisor: Dr U McClurg

Year round applications PhD Research Project Self-Funded PhD Students Only

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Deciphering the evolution of male sexual ornaments and female preference in stalk-eyed flies

University of Sheffield School of Biosciences

The selected candidate will conduct cutting-edge research to investigate the evolution of male sexual ornaments and the role of female preference in shaping these traits. Read more

Supervisor: Dr A Wright

Year round applications PhD Research Project Self-Funded PhD Students Only

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A chemical engine to produce mechanical force: towards a physio-chemical model of heart cells

University of Reading Department of Biomedical Engineering

Living systems are complex, and are based on the basic building blocks of genes, proteins, chemical reactions, and physical forces. Read more

Supervisors: Dr Y Hayashi, Dr Z Wang, Dr N Vasudevan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the biology and utility of Giant Viruses (Jumbo-bacteriophages). (ref: SF22/HLS/APP/Smith-Nelson)

Northumbria University Faculty of Health and Life Sciences

The bacteriophage research group at Northumbria University are seeking a highly motivated and talented PhD candidates to join our team and investigate the biology and potential applications of jumbo bacteriophages. Read more

Supervisor: Prof D Smith

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding L1 ORF1p and Pin1 interaction to exploit it as a therapeutic strategy for liver cancer (ref: SF22/HLS/APP/SHUKLA)

Northumbria University Faculty of Health and Life Sciences

Primary liver cancer, predominantly hepatocellular carcinoma (HCC), is the 4th commonest cause of cancer death globally. Read more

Supervisor: Dr R Shukla

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification of transcriptomic signatures of autism-like neurodevelopmental disorder

The University of Manchester Faculty of Biology, Medicine and Health

The overarching aim of this project is to define transcriptional patterns and identify new genetic elements essential for the correct development of the human brain. Read more

Supervisors: Dr PG Grzechnik, Dr A J Whitmarsh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing new treatments for leishmaniasis

University of Strathclyde Department of Pure and Applied Chemistry

Leishmaniasis. Read more

Supervisor: Dr FS Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Towards the development of a novel class of broad-spectrum anti-infective drugs

University of Strathclyde Department of Pure and Applied Chemistry

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Supervisor: Dr FS Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding how electrical communication can regulate metabolic cycles in bacteria biofilms

University of Reading Department of Biomedical Engineering

Project Overview. A biofilm is a robust form of bacteria colony resistant to antibiotics. They have significant impacts on a multitude of industries impacting health and industrial processes such as in food production and water security. Read more

Supervisors: Dr Y Hayashi, Dr G Barrett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Where has all of the carbon gone? Understanding the molecular mechanisms of long-term soil carbon capture

The University of Manchester Department of Earth and Environmental Sciences

Soils, while unglamorous, form the basis of the terrestrial biosphere and are ultimately the source of the majority of the food that we eat, yet fundamental aspects of how soils form and how they store carbon are poorly understood. Read more

Supervisors: Prof D Cameron, Dr S Nixon

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Targeting ageing and neurodegenerative diseases using the fruit-fly Drosophila melanogaster

Royal Holloway, University of London School of Biological Sciences

In the last 20 years the fruit fly Drosophila melanogaster emerged as a pre-eminent model system for studying changes that occur during both normal and pathological ageing (~75 per cent of the genes that cause disease in humans are also found in the fruit fly!). Read more

Supervisor: Dr H Augustin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genomic approaches to understanding molluscan parasites

University of Nottingham School of Life Sciences

Snails and slugs cause worldwide problems, both in terms of direct damage to crops, and as intermediate vectors for diseases of farm animals and humans (e.g. Read more

Supervisors: Dr A Davison, Dr C M Wade

Year round applications PhD Research Project Self-Funded PhD Students Only

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Saving the planet through carbon recycling: engineering bacterial capture of gasified waste for bioplastics production

University of Nottingham School of Life Sciences

Wider context. Climate change caused by the release of greenhouse gases from fossil fuels and through change of land use threatens life on our planet. Read more

Supervisors: Dr K Winzer, Prof N Minton

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 220 genes PhD Projects, Programmes & Scholarships

genes PhD Projects, Programmes & Scholarships

We have 220 genes PhD Projects, Programmes & Scholarships

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