lung disease PhD Projects, Programmes & Scholarships

Understanding the role of mucin genetic variation in lung disease

University of Leicester Department of Genetics and Genome Biology

Research Group: Human & Medical Genetics

Understanding how genetic variation contributes to lung diseases is important in understanding how the disease develops and identifying potential molecular targets for therapy. Read more

Supervisor: Prof E Hollox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of extracellular vesicles in lung epithelial cell communication in health and disease

University of Salford School of Science, Engineering and Environment

There is an opportunity to apply for a widening participation scholarship (available to UK candidates or those eligible for UK fees) can be found here. Read more

Supervisor: Dr P Miklavc

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

University of Leeds Faculty of Medicine and Health

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Supervisors: Prof L Houghton, Dr D Peckham

Year round applications PhD Research Project Self-Funded PhD Students Only

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Modelling the respiratory microbiome in chronic lung disease and healthy ageing

University of Birmingham Institute of Microbiology and Infection

The Respiratory Microbiome Group seeks to understand the interactions between complex communities of bacteria, fungi and viruses with the human respiratory tract in both disease (acute infections and chronic lung disease) and in health or healthy ageing. Read more

Supervisors: Dr MJ Cox, Dr K Belchamber

Year round applications PhD Research Project Self-Funded PhD Students Only

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Deciphering the cell death-dependent fibrotic niche following lung injury

University of Edinburgh College of Medicine and Veterinary Medicine

Research Group: Centre for Inflammation Research

Background. Lung disease causes 1 in 5 deaths globally with limited treatment advances for many acute and chronic respiratory conditions. Read more

Supervisors: Dr C Lucas, Dr DD Dorward, Dr P Ramachandran

13 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Defining the mechanistic basis of Aspergillus fumigatus and Non-tuberculous mycobacteria coinfection

The University of Manchester Faculty of Biology, Medicine and Health

Respiratory infections caused by bacteria, fungi and viruses are a global cause of death according to the WHO. Respiratory coinfections are on the rise and in general linked with poor patient outcomes. Read more

Supervisors: Dr S Gago, Dr CK Kosmidis, Prof L Tabernero

Year round applications PhD Research Project Self-Funded PhD Students Only

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Immune regulation of lung repair, and long-term consequences of infection

University of Edinburgh School of Biological Sciences

This project is one of 14 four year PhD Studentships funded by Medical Research Scotland (MRS) (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO). Read more

Supervisors: Prof G Perona-Wright, Dr S Jenkins

14 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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PROTEOTRANSCRIPTOMIC INVESTIGATION OF EQUINE EXERCISE-INDUCED PULMONARY HAEMORRHAGE: A POTENTIAL NEW ERA OF CLINICAL DIAGNOSTICS

University of Surrey School of Veterinary Medicine

**The project can be adopted/modified to suit the successful candidates’ scientific interest in consultation with the supervisory team.**. Read more

Supervisors: Dr S Armstrong, Dr K Jeevaratnam

1 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Dysfunctional antifungal potency of the respiratory mucosa in COPD

The University of Manchester Faculty of Biology, Medicine and Health

Inhalation of Aspergillus fumigatus spores cause >3,000,000 chronic and >200,000 invasive diseases annually worldwide. Invasive aspergillosis carries a 50% mortality rate overall, but mortality rate approaches 100% if diagnosis is delayed or missed and it is >75% in certain cohorts of patients, such as COPD sufferers. Read more

Supervisors: Dr M Bertuzzi, Dr J.H Herbert, Dr S Gago

Year round applications PhD Research Project Self-Funded PhD Students Only

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Functional effects of variable number tandem repeat expansions in idiopathic pulmonary fibrosis

University of Leicester Department of Genetics and Genome Biology

Research Group: Human & Medical Genetics

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by the formation of scar tissue in the lungs. Read more

Supervisor: Prof E Hollox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Drug repurposing for the treatment of aspergillosis

The University of Manchester Faculty of Biology, Medicine and Health

The mould Aspergillus fumigatus was classified by the WHO as a critical priority pathogen in 2022. It causes a spectrum of invasive, allergic and chronic disease. Read more

Supervisors: Dr CK Kosmidis, Prof D Ashcroft, Dr M Bottery, Dr M Bromley

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function. At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

Supervisors: Prof S Arthur, Dr H McSorley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular characterisation of post-tuberculous bronchiectasis

University of Dundee School of Medicine

Tuberculosis is a major health problem is Iraq and globally. While treatment of TB, including MDR TB has greatly improved resulting in high rates of clinical cure, many patients with TB are left with persisting lung disease including airflow obstruction and bronchiectasis. Read more

Supervisors: Prof J Chalmers, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Graduate Training Assistant (GTA) PHD scholarship, Sheffield Hallam University: Protective heat acclimation for older adults and physically and socially vulnerable populations

Sheffield Hallam University Sport and Physical Activity Research Centre

Applications are invited for Graduate Teaching Assistant (GTA) PhD scholarships in Sport and Physical Activity, Sheffield Hallam University, commencing 1st October 2024. . Read more

Supervisor: Dr A Purvis

15 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Genotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis

The University of Manchester Faculty of Biology, Medicine and Health

Chronic pulmonary aspergillosis (CPA) is a progressive infection affecting patients with chronic lung disease. It significantly affects quality of life and mortality. Read more

Supervisors: Dr CK Kosmidis, Dr M Bromley, Dr R Richardson, Dr M Bottery, Prof T Hussell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

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Repurposing and enriching cardiovascular risk prediction model to identify people at risk of cancer – UCL (part of Health Data Research UK’s Big Data for Complex Disease Driver Programme)

Health Data Research UK Big Data for Complex Diseases (BDCD)

Risk-stratified management of cardiovascular disease (CVD), where people without established disease receive preventative interventions and monitoring based on their 10-years predicted risk, has been highly successful to ensure healthcare resources are allocated to those most likely to benefit. Read more

Supervisor: Dr FS Schmidt

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Multi-omics data analysis for critical disease prediction

Brunel University London Chemical Engineering

Personalised treatment is a new and strategic approach to separates patients into different groups based on their personal response or risk of disease so that treatments can be tailored to the individual patient. Read more

Supervisor: Dr Y Yang

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the innate immune response in RSV and HMPV infection

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£46,000 total). Read more

Supervisor: Dr M Triantafilou

31 May 2024 PhD Research Project Self-Funded PhD Students Only

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Using genome sequencing to find the cause of undiagnosed rare conditions affecting bowel, heart, lung or brain in adults

University of Sheffield School of Medicine and Population Health

In the UK, a rare condition is one that affects fewer than 1/2000 people. Around 70% of rare conditions have a genetic cause (ie are caused by a change… Read more

Supervisor: Dr A McNeill

Year round applications PhD Research Project Self-Funded PhD Students Only

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Driving phenotypic plasticity and metastasis in small cell lung cancer

The University of Manchester Faculty of Biology, Medicine and Health

Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Underlying this aggressiveness is intra-tumoural heterogeneity driven by phenotypic plasticity wherein tumour cells transition from a neuroendocrine (NE) to a non-neuroendocrine (non-NE) phenotype. Read more

Supervisors: Prof A Malliri, Dr K Simpson, Prof C Dive

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD Cognitive function and balance in bronchiectasis

King’s College London Faculty of Life Sciences & Medicine

Bronchiectasis is a chronic lung condition that was previously neglected for years. Non-pharmacological management for bronchiectasis includes airway clearance techniques and pulmonary rehabilitation. Read more

Supervisor: Dr A Spinou

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD Digital health in bronchiectasis

King’s College London Faculty of Life Sciences & Medicine

Bronchiectasis is a chronic lung condition that was previously neglected for years. Non-pharmacological management for bronchiectasis includes airway clearance techniques and pulmonary rehabilitation. Read more

Supervisors: Dr A Spinou, Dr MD Davare

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

The University of Manchester Faculty of Biology, Medicine and Health

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

Supervisors: Dr S Nagarajan, Dr HH Harrison, Prof R Clarke, Dr I Iqbal

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Live cell imaging of epithelial cancer cell proliferation for therapy

University of Leeds Faculty of Biological Sciences

The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Prof A Divan, Dr S Ponnambalam, Dr M A Harrison

Year round applications PhD Research Project Self-Funded PhD Students Only

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Aberrant bone morphogenetic protein signalling in precision medicine of targeting tyrosine receptor kinase in solid tumours

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£55,000 total). Read more

Supervisor: Dr L Ye

31 May 2024 PhD Research Project Self-Funded PhD Students Only

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MSc By Research: Using hypomethylating agents to prevent respiratory infections in older adults

Aberdeen University School of Medicine, Medical Sciences & Nutrition

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Supervisors: Dr c Quin, Prof H Wilson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy

Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School

Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more

Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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We have 40 lung disease PhD Projects, Programmes & Scholarships

lung disease PhD Projects, Programmes & Scholarships

We have 40 lung disease PhD Projects, Programmes & Scholarships

Understanding the role of mucin genetic variation in lung disease

Selective targeting of furin for the treatment of fibrotic lung disease.

The role of extracellular vesicles in lung epithelial cell communication in health and disease

Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

Modelling the respiratory microbiome in chronic lung disease and healthy ageing

Deciphering the cell death-dependent fibrotic niche following lung injury

Defining the mechanistic basis of Aspergillus fumigatus and Non-tuberculous mycobacteria coinfection

Immune regulation of lung repair, and long-term consequences of infection

PROTEOTRANSCRIPTOMIC INVESTIGATION OF EQUINE EXERCISE-INDUCED PULMONARY HAEMORRHAGE: A POTENTIAL NEW ERA OF CLINICAL DIAGNOSTICS

Dysfunctional antifungal potency of the respiratory mucosa in COPD

Functional effects of variable number tandem repeat expansions in idiopathic pulmonary fibrosis

Drug repurposing for the treatment of aspergillosis

MSc by Research: Molecular characterisation of the factors driving lung fibrosis

Molecular characterisation of post-tuberculous bronchiectasis

Graduate Training Assistant (GTA) PHD scholarship, Sheffield Hallam University: Protective heat acclimation for older adults and physically and socially vulnerable populations

Genotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis

Preclinical testing of collagen synthesis inhibitors for fibrotic disease

Repurposing and enriching cardiovascular risk prediction model to identify people at risk of cancer – UCL (part of Health Data Research UK’s Big Data for Complex Disease Driver Programme)

Multi-omics data analysis for critical disease prediction

Investigating the innate immune response in RSV and HMPV infection

Using genome sequencing to find the cause of undiagnosed rare conditions affecting bowel, heart, lung or brain in adults

Driving phenotypic plasticity and metastasis in small cell lung cancer

PhD Cognitive function and balance in bronchiectasis

PhD Digital health in bronchiectasis

(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

Live cell imaging of epithelial cancer cell proliferation for therapy

Aberrant bone morphogenetic protein signalling in precision medicine of targeting tyrosine receptor kinase in solid tumours

MSc By Research: Using hypomethylating agents to prevent respiratory infections in older adults

Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

We have 40 lung disease PhD Projects, Programmes & Scholarships

lung disease PhD Projects, Programmes & Scholarships

We have 40 lung disease PhD Projects, Programmes & Scholarships

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