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medicinal PhD Projects, Programs & Scholarships

We have 30 medicinal PhD Projects, Programs & Scholarships

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  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
  Dr I Dreveny
Applications accepted all year round

Funding Type

PhD Type

Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
  Evolutionary Perspectives on Medicinal Plant Use
  Prof J A Hawkins
Applications accepted all year round

Funding Type

PhD Type

This project encompasses 1. evolutionary aspects of medicinal plant use and 2. authentication. You will collect DNA sequence data at the level of a whole flora and at the level of a genus.
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round

Funding Type

PhD Type

In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
  Novel Cyclic Peptides for Biomedical Imaging and Therapeutic Targeting
  Prof M Zanda
Applications accepted all year round

Funding Type

PhD Type

Cyclic Peptides have a wide range of applications as drugs and diagnostics, and have often higher receptor affinity, metabolic stability and better pharmacokinetic properties compared to their linear counterparts, but their synthesis still presents significant challenges.
  Total synthesis of marine polycyclic ether natural products to tackle Alzheimer’s disease
  Dr M Kimber
Application Deadline: 30 September 2019

Funding Type

PhD Type

This project will develop an efficient asymmetric synthesis of marine polycyclic ether natural products.
  Neuropeptide Research - PhD Opportunity at a World Class Institution
  Dr M Muttenthaler, Assoc Prof C Schroeder, Assoc Prof I Vetter
Applications accepted all year round

Funding Type

PhD Type

We are seeking talented and highly motivated PhD candidates for the following multidisciplinary project. Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round

Funding Type

PhD Type

Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships

Funding Type

PhD Type

Applications are invited from suitably qualified graduates for fully funded 4-year PhD studentships in the area of Molecular Sciences for Medicine (MosMed) and will focus on unmet medical needs.
  Targeting ovarian cancer using fragment-based drug discovery
  Prof I McNeish
Applications accepted all year round

Funding Type

PhD Type

Funded by the CDT in Chemical Biology. Innovation in Life Sciences – 1+3 year PhD studentships. Supervisors. Professor Iain McNeish | Professor Alan Armstrong | Dr David Mann | Dr James Bull.
  Novel synthetic approaches to antimicrobial natural products and investigations of their bioactivity
  Prof A Malkov
Applications accepted all year round

Funding Type

PhD Type

The aim of the project is to develop new highly effective anti-tubercular agents. Previously, it has been established that terpenes isolated from marine organisms possess a number of important antibacterial properties.
  EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships

Funding Type

PhD Type

Applications are invited from suitably qualified graduates for fully funded 4-year PhD studentships in the area of Molecular Sciences for Medicine (MosMed) and will focus on unmet medical needs.
  Synthesis and study of metal chelators against neurodegenerative diseases and cancer (ref:SF18/APP/Tetard)
  Dr D Tetard
Applications accepted all year round

Funding Type

PhD Type

Because of the involvement of metal in numerous biological processes, in particular in oxidative stress and enzymatic action, the study of metal chelators as potential therapeutic agents has been growing.
  Evaluation of natural plant based botanicals as alternative to therapeutic antibiotics
  Dr C Situ
Applications accepted all year round

Funding Type

PhD Type

It has become widely recognised that antimicrobial resistance (AMR) is one of the biggest health threats that mankind faces encompassing huge health and economic burdens on governments and societies in every region of the globe.
  Research Assistantship is Available for PhD in Pharmaceutical Sciences

Funding Type

PhD Type

The Graduate Program in Pharmaceutical Sciences at Texas Tech University Health Sciences Center (TTUHSC) School of Pharmacy in Amarillo, Texas is accepting applications from highly competent college graduates for admission into the Ph.D.
  New Dimensions in Cannabinoid Receptor 2 Therapeutic Development: Exploring Spatial and Temporal Signalling Bias
  Dr N Grimsey
Applications accepted all year round

Funding Type

PhD Type

Compounds derived from Cannabis sativa, termed “cannabinoids”, primarily exert their effects via two G protein-coupled receptors (GPCRs), Cannabinoid Receptors 1 and 2 (CB1 and CB2).
  Chemical modulation of cellular redox balance for cancer treatment
  Dr I Romero-Canelon
Applications accepted all year round

Funding Type

PhD Type

Platinum complexes, cisplatin, oxaliplatin and carboplatin, are the most widely used anticancer drugs. However, these DNA-targeting treatments are a low selectivity approach with deleterious consequences and a high incidence of resistance.
  Precious metals in the fight against cancer
  Dr I Romero-Canelon
Applications accepted all year round

Funding Type

PhD Type

Platinum-based complexes, Cisplatin, Oxaliplatin and Carboplatin, are the most widely used chemotherapeutics, nonetheless there is a major unmet clinical need for new treatments that expand the range of treatable cancers and overcome inherent and acquired platinum resistance.
  Activity based proteomic probes for profiling CYP2W1 in cancer tissues
  Research Group: Institute of Cancer Therapeutics
  Dr C Sutton, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Cytochromes P450 (CYPs) are a superfamily of mixed function oxidases of which CYP1-4 subfamily members are unique in their ability to oxidise drugs.
  Development of heterocyclic pharmacophores using diversity-oriented synthesis
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof L Patterson
Applications accepted all year round

Funding Type

PhD Type

Diversity-oriented synthesis (DOS) is a modern chemical tool, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression.
  Tetrazines as Traceless Carriers for Polar Drugs
  Research Group: Medicines Development and Pharmaceutical Sciences
  Dr R Wheelhouse, Prof P Loadman
Applications accepted all year round

Funding Type

PhD Type

A recent invention in Bradford has identified a new carrier molecule that reduces the polarity of polar drugs.
  Identification of novel anticonvulsant compounds
  Prof R Baines, Dr S Freeman, Prof S Allan
Applications accepted all year round

Funding Type

PhD Type

Epilepsy and other associated seizures are a significant health concern, occurring in an estimated 1-2% of the world’s population.
  Design, Synthesis and Biological Evaluation of novel inhibitors of the JAK-STAT signalling pathway with potential application as immune oncology agents
  Dr R Whitehead, Dr K Finegan, Prof N Turner
Applications accepted all year round

Funding Type

PhD Type

Small molecule inhibitors of the JAK-STAT signalling pathway often possess interesting biological properties with many displaying potent anti-proliferative activity towards cancer cell lines.
  CRISPR-Cas9 genome editing and super-resolved live cell imaging to study the extracellular microenvironment at the single molecule level
  Dr A Piccinini, Prof D Heery
Applications accepted all year round

Funding Type

PhD Type

The three-dimensional space around and between mammalian cells is filled with a complex network of extracellular matrix (ECM) molecules, which instruct fundamental processes such as cell survival, differentiation and migration, in addition to providing structural support for cells.
  FOXA1 mutations in Lobular Breast Cancer: Reprogramming Responses to Tamoxifen
  Prof D Heery, Dr S Johnston
Applications accepted all year round

Funding Type

PhD Type

Tumours of the breast are often hormone-dependent, meaning their growth is driven by steroid hormones such as estrogen. This hormone acts upon the estrogen receptor (ER), which together with other transcription factors such as FOXA1 drives tumour growth.
  Transdermal and Topical Drug Delivery: developing novel formulations to increase drug delivery into and through skin
  Prof A Williams
Applications accepted all year round

Funding Type

PhD Type

Human skin is a remarkable self-repairing barrier that controls the ingress of environmental contaminants and regulates water loss from the body.
  New directions in Cu-catalysed cross-coupling
  Dr AJB Watson
Applications accepted all year round

Funding Type

PhD Type

Fully funded PhD studentships, in collaboration with AstraZeneca, are available in the lab of Dr Allan Watson at the University of St Andrews.
  In-situ Monitoring of Flowing Pharmaceutical Powders
  Dr D Markl, Dr A Nordon
Application Deadline: 31 July 2019

Funding Type

PhD Type

As much as 70% of potentially efficacious medicinal compounds never become pharmaceutical products due to difficulties in manufacturing them.
  PhD Study in the School of Pharmacy and Pharmaceutical Sciences

Funding Type

PhD Type

PhD candidate applications are sought to a number of disciplines within the School of Pharmacy and Pharmaceutical Sciences at the University of Sunderland.
  Brønsted Acid Catalysed Asymmetric Synthesis of Cyclic Ethers
  Dr P Clarke
Applications accepted all year round

Funding Type

PhD Type

Over recent years there has been a drive by medicinal chemists to explore more 3-dimensional areas of chemical space. Cyclic ethers, such as the tetrahydropyran (THP) and the tetrahydrofuran (THF) rings, are the most common and 6th most common saturated heterocyclic function present in marketed pharmaceuticals.
  Development of chemical tools to interrogate cannabinoid receptors
  Dr A Vernall
Applications accepted all year round

Funding Type

PhD Type

Suitable for an international or New Zealand candidate to work on the design and synthesis of small molecules and chemical tools to study cannabinoid type 2 receptors.
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