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membrane PhD Projects, Programs & Scholarships

We have 132 membrane PhD Projects, Programs & Scholarships

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  Membrane protein biogenesis and quality control
  Dr R Hegde
Application Deadline: 3 December 2019

Funding Type

PhD Type

Approximately 20-25% of genes in humans encode integral membrane proteins that must be selectively targeted to and inserted into the endoplasmic reticulum (ER) membrane.
  Membrane protein misfolding and disease: quality control pathways
  Dr L Swanton, Prof P Woodman
Applications accepted all year round

Funding Type

PhD Type

Misfolded proteins represent a continuous threat to cell viability, and if allowed to accumulate, can disrupt cellular function and induce cell death.
  Protein sensitivity of membrane curvature
  Prof R Vácha
Application Deadline: 31 October 2019

Funding Type

PhD Type

The control of biological membrane shape and composition is vital to eukaryotic life. The shape is so specific that it allows us to recognize various organelles in the cell.
  Development of Novel Crystallization Methods for Integral Membrane Proteins
  Dr G Patchornik
Applications accepted all year round

Funding Type

PhD Type

Our research is focused on one of the major barriers in Structural biology. growing high quality three dimensional (3D) crystals of integral membrane proteins for structural analysis.
  Sustainable Lithium Mining and Recycling using Membrane Technology
  Dr Y Huang
Application Deadline: 11 November 2019

Funding Type

PhD Type

With continual technological advancements in mobile devices and electric cars, the global demand for lithium has quickly outpaced the rate at which it can be mined or recycled.
  Mechanism of Bacterial Resistance to Antimicrobial Peptides
  Prof Mibel Aguilar
Application Deadline: 31 March 2020

Funding Type

PhD Type

Antibiotic resistance continues to emerge and intensify.
  Investigating the role of membrane transporters in early development
  Research Group: Chromatin & Development
  Dr M Percharde, Dr L Fets
Application Deadline: 1 December 2019

Funding Type

PhD Type

This is a joint project between the Chromatin and Development and the Drug Transport and Tumour Metabolism groups within the MRC LMS.
  Transport of essential nutrients across the outer membrane of a bacterial pathogen
  Dr M Thomas
Applications accepted all year round

Funding Type

PhD Type

Gram-negative bacteria possess a second membrane, the outer membrane (OM), that serves as an additional line of defence against noxious agents, including antibiotics.
  Complement resistance mechanisms by multi-drug resistant Klebsiella pneumonia
  Prof S Rooijakkers, Prof A Blom
Application Deadline: 10 November 2019

Funding Type

PhD Type

The aim of this project is to characterize complement evasion molecules in the opportunistic bacterium Klebsiella pneumoniae (K. pneumoniae) where carbapenem-resistance grew from 1.6% to 10.4% in 10 years.
  Marie Sklodowska-Curie Early Stage Researcher (ESR) - Understanding lipid membranes at the nanoscale through nonlinear optical microscopy at membrane-nanoparticle interfaces
  Prof P Borri
Application Deadline: 17 October 2019

Funding Type

PhD Type

**Interviews will be held on Thursday 24th October 2019 and invited applicants will be required to give a 10 minute presentation detailing research work relevant to the position**.
  Materials development for proton exchange membrane based fuel cells and electrolysers
  Prof P Kelly
Application Deadline: 18 October 2019

Funding Type

PhD Type

Widescale deployment of fuel cell and electrolyser technologies is hindered by high precious metal loadings. This project will develop novel and advanced materials towards reducing and eliminating precious metal usage.
  Self-association of the Alzheimer’s peptide Aβ on membrane surfaces
  Prof M P Williamson
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease is a neurodegenerative disease that is particularly common amongst the elderly. It accounts for about 65% of all cases of dementia, and affects about 6% of people over 65, rising to 50% of people over 85.
  Sorting old from new: protein assembly and turnover in the Gram-negative outer membrane
  Dr C G Baumann, Dr M A Fascione
Application Deadline: 30 June 2020

Funding Type

PhD Type

Gram-negative bacteria have evolved to survive in diverse ecological niches. Some species are pathogenic, while others colonise the mammalian gut and aid food digestion.
  Structural and Biophysical Characterisation of Novel Membrane Protein Ion Channels (Chinese candidates / China mainland only)
  Research Group: School of Biomedical Sciences
  Dr C Pliotas
Application Deadline: 8 January 2020

Funding Type

PhD Type

Research in the Pliotas group (https://www.pliotasgroup.org/) focuses on the investigation of molecular mechanisms which underlie the structure and function of integral membrane proteins, in particular ion channels.
  Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease
  Prof M Lowe, Prof V Allan
Applications accepted all year round

Funding Type

PhD Type

Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway.
  Pathophysiology of red cell membrane permeability
  Dr J Gibson
Applications accepted all year round

Funding Type

PhD Type

Our project investigates how red cell membrane permeability is altered in pathophysiological states.
  Advancing our understanding of fundamental cellular processes by investigating membrane contact sites.
  Dr P Pryor, Dr C G Baumann
Application Deadline: 30 June 2020

Funding Type

PhD Type

An emerging, exciting area of research is that of membrane contact site (MCS) biology.
  Imaging viruses and cells by electron cryomicroscopy (cryoEM)
  Dr P Rosenthal
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Peter Rosenthal’s Group based at the Francis Crick Institute (the Crick). Our group studies the architecture of large protein assemblies in order to understand basic molecular mechanisms that control protein and membrane traffic in the cell and in virus infection.
  Physical mechanisms of evolution of cell trafficking
  Dr A Saric
Applications accepted all year round

Funding Type

PhD Type

Complex eukaryotic cells first appeared on earth over a billion years ago. Such cells are built out of physical compartments separated from each other by membrane boundaries.
  Computational Fluid Dynamics Evaluation of Mixing Zones in Extra Corporeal Membrane Oxygenation Circuits to Prevent Brain Injury
  Dr J Pauls
Applications accepted all year round

Funding Type

PhD Type

The Critical Care Research Group (CCRG), based at the The Prince Charles Hospital (TPCH) in Brisbane, Australia, is seeking highly motivated, skilled and committed PhD candidates to join our multidisciplinary and international research team to commence a PhD project.
  Surgical approaches and acute response to small-package implantation of the tympanic membrane
  Prof S Lloyd, Dr M Stone
Application Deadline: 16 November 2019

Funding Type

PhD Type

Most current implantable hearing prostheses require an external package to capture and process sound before transmission to the implant.
  Mechanistic dissection of interplay between membrane traffic and apoptosisby mutations in the endosomal sorting regulatory protein Vps45.
  Prof N Bryant, Dr C MacDonald
Application Deadline: 5 January 2020

Funding Type

PhD Type

Eukaryotic cells have to coordinate a large number of cellular processes in. order to function properly. Understanding how this is achieved is critical for.
  A mechanistic understanding of circadian clock-dependent regulation of the secretory pathway
  Prof K E Kadler, Dr Q-J Meng, Dr J Swift
Applications accepted all year round

Funding Type

PhD Type

The protein secretory pathway comprises a series of membranous compartments and transport vesicles that cells use to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
  Microtubule motors in cell migration and integrin trafficking
  Prof V Allan, Prof P Woodman, Dr P Caswell
Applications accepted all year round

Funding Type

PhD Type

Cell migration is vital for the development and health of multicellular organisms. However, enhanced cell migration is also a hallmark of cancer cells, and contributes greatly to metastasis.
  GW4 BioMed MRC DTP PhD studentship: Using nanotechnology, structural biology and genome editing to study how fungal receptors promote the spread of lethal diseases
  Dr N Brown
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  Elucidating the mechanisms of phospholipid transport in Gram-negative bacteria
  Research Group: BBSRC MIBTP
  Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

This project focuses on characterising the fundamental process of outer membrane lipid transport in Gram-negative bacteria, a largely unknown process which is only now being revealed.
  Experimental topics in the manipulation of sound using metamaterials and metasurfaces
  Prof A P Hibbins, Prof J R Sambles
Application Deadline: 31 December 2019

Funding Type

PhD Type

The studentship is part of the UK’s Centre of Doctoral Training in Metamaterials (XM2) based in the Departments of Physics and Engineering on the Streatham Campus in Exeter.
  Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes
  Prof R A Frazier, Dr R Green
Applications accepted all year round

Funding Type

PhD Type

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals.
  Investigating the role of the mechanosensor channel Piezo1 in human disease
  Dr K Erdmann
Applications accepted all year round

Funding Type

PhD Type

Piezo proteins are ion channels that are gated by mechanical stimuli like stretch or shear stress. In mammalians there are two Piezo isoforms (Piezo1 and Piezo2) with largely different expression pattern.
  Supra-molecular architecture of neurotransmitter receptor complexes
  Dr R Aricescu
Application Deadline: 3 December 2019

Funding Type

PhD Type

Chemical synapses are cellular connectors that define the organization and function of neuronal circuits and, as a result, the fundamental ability of the brain to acquire and store information.
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