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We have 43 mr PhD Projects, Programmes & Scholarships

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mr PhD Projects, Programmes & Scholarships

We have 43 mr PhD Projects, Programmes & Scholarships

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Mendelian Randomisation for mediation analysis with multiple mediators: theory and applications

Rationale. Many of an individual’s traits are observationally associated with their health outcomes. Understanding the relationships between these factors is critical to effective public health intervention. Read more

Designing Meaningful Mixed Reality Experiences

The aim of this research project is to investigate the design of Mixed Reality Experiences, with the long-term objective of investigating how they can be designed, developed and deployed in engaging, impactful, and ultimately more meaningful ways, in any given application context. Read more

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

Rationale. Mendelian Randomization (MR) is a genetic epidemiology method which utilises variants sourced from genome-wide association studies (GWAS) to assess causality between risk/protective factors and disease outcomes in a manner less biased to observational studies(1). Read more

How does parental education increase risk to ADHD in the offspring?

Rationale. Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental condition, characterised by persistent difficulties in the areas of attention span/impulse control. Read more

Causal risk factors and biological mechanisms for colorectal cancer risk

Rationale. Diet and lifestyle are likely to play an important role in colorectal cancer risk; obesity, low levels of physical activity, red and process meat consumption and low intake of dietary fibre have all been shown to predict colorectal cancer risk. Read more

Community-centred heritage and language revitalisation powered by creative technologies and immersive storytelling.

This PhD will explore how creative technologies and immersive storytelling can support the revitalisation of the endangered heritage, languages, and identities of minority groups, as well as opportunities for social integration across marginalised communities. Read more

NIHR Leeds BRC: Development and application of fast Magnetic Resonance Spectroscopic Imaging methods for metabolic profiling

Altered metabolism is a hallmark of many disease states, including cardiovascular and musculoskeletal conditions. Importantly, metabolic profiles may be patient-specific and may for example indicate susceptibility to treatment or malignancy. Read more

Integrative genomics prioritisation of drug targets

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Understanding the role of adiponectin in kidney disease development at a population level

Reduced circulating adiponectin levels are associated with poor outcome in patients with diabetic kidney disease (DKD) (1). Adiponectin has been shown to be protective against the development of DKD in Type 2 diabetic models (2, 3, 4). Read more

Epilepsy and the ageing brain

Our ability to remember ‘where I put my car keys today’ instead of ‘where I put them yesterday’ depends on a computational process called pattern separation. Read more

Using ultrasound thalamotomy as an opportunity to understand the contributions of the human thalamus to decision making and learning

The contribution of the human thalamic nuclei to decision making are poorly understood and a focus of considerable interest given their routine use as safe targets for functional neurosurgery in tremor and Parkinson's disease. Read more

Prognostic Markers in Bladder Cancer

Bladder cancer is the ninth most common malignant disease in the world (Ferlay et al., 2015). Following removal of diseased tissue, cancer reoccurs in approximately 40% of patients and in 8% it metastasises into other tissues. Read more

PhD Studentship: Safer Scoring: Application of mixed methods evaluation to understand ward strain

We seek an outstanding early career researcher or clinician to be appointed to a 3-year PhD studentship to collaborate on a series of projects using mixed methods to explore aspects of patient safety related to effective management of acute deterioration (acute illness) across whole wards/departments, hospitals and patient pathways. Read more

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