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pharmacology PhD Projects, Programs & Scholarships

We have 112 pharmacology PhD Projects, Programs & Scholarships

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  Sex dimorphisms in innate immunity, inflammatory pathology, and ageing
  Research Group: Institute of Immunology & Infection Research
  Dr J Regan, Dr S Jenkins
Application Deadline: 5 January 2020

Funding Type

PhD Type

Ageing is the largest risk factor for the developed world’s biggest killers, and the impact of age-related disease is one of society’s foremost challenges.
  An exploration of the links between mitochondrial function and splicing regulation. PhD in Medical Studies (SWBio DTP)
  Dr L Harries
Application Deadline: 2 December 2019

Funding Type

PhD Type

Lead Supervisor. Professor Lorna Harries, College of Medicine and Health, University of Exeter. Additional Supervisors. - Professor Mark Lindsay, Department of Pharmacy and Pharmacology, University of Bath.
  Investigating the remodelling of inhibitory brain circuits in early Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Prof A Randall
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Professor Andrew Randall, Medical School, College of Medicine and Health, University of Exeter. Dr Jonathan Witton, College of Medicine and Health, University of Exeter.
  Regulation of food preference and reward by the brain. PhD in Medical School (MRC GW4 BioMed DTP)
  Dr K Ellacott
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Kate Ellacott, Institute of Biomedical and Clinical Sciences, Medical School, University of Exeter. Prof Anthony Pickering, Pharmacology and Physiology, University of Bristol.
  The influence of JAKMIP1, a key risk gene for autism, on neural circuit function. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr A Oguro-Ando
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Asami Oguro-Ando, The Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter.
  The neural circuit basis of spatial memory loss in Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr J Witton
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Jonathan Witton, College of Medicine and Health, University of Exeter. Dr Michael Ashby, Faculty of Life Sciences, University of Bristol.
  How does the vascular matrix environment influence platelet activation?
  Dr S Calaminus
Application Deadline: 31 March 2020

Funding Type

PhD Type

The platelet is a blood cell that plays a key role in the prevention of bleeding. For platelets to form a clot or thrombus effectively, they must rearrange their actin cytoskeleton to withstand high shear stress from blood flow in the arteries.
  Identification of novel glucose-dependent alterations responsible for platelet dysfunction in Type 2 diabetes.
  Prof Tim Palmer, Dr F Rivero
Application Deadline: 31 March 2020

Funding Type

PhD Type

Type 2 diabetes mellitus (T2DM) is a growing global healthcare problem. Clinical findings suggest that more than 70% of patients with T2DM will die of cardiovascular diseases (CVDs) including heart attack and stroke.
  Identification of novel glucose-dependent alterations responsible for vascular dysfunction in Type 2 diabetes.
  Prof Tim Palmer, Dr R Sturmey
Application Deadline: 31 March 2020

Funding Type

PhD Type

Diabetes is a growing global healthcare problem. The majority of people living with diabetes have Type 2 diabetes mellitus (T2DM), characterised by a resistance of the body to the action of insulin.
  Modulation of platelet-mediated innate immune responses in chronic lymphocytic leukaemia
  Dr M Arman
Application Deadline: 31 March 2020

Funding Type

PhD Type

Chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia in the Western World. B-cell receptor-induced intracellular signals are critical for the survival of leukaemia cells and disruption of this pathway by the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib is a highly effective CLL therapy.
  Platelets and hypoxia: how do varying oxygen concentrations affect platelet function and signalling?
  Dr M Arman
Applications accepted all year round

Funding Type

PhD Type

Platelets have key functions in regulating haemostasis and maintaining vascular integrity, which can cause cardiovascular disease if unbalanced.
  Precision-cut lung slices to investigate the effect of human rhinovirus on cough and airway inflammation
  Dr L Sadofsky
Application Deadline: 31 March 2020

Funding Type

PhD Type

The human Rhinovirus (RV) is the major cause of the common cold. There are no current treatments or vaccines for the virus other than over the counter preparations to alleviate symptoms.
  Re-purposing diabetes medicines to manage bleeding complications in myeloproliferative neoplasms.
  Prof Tim Palmer, Dr D Allsup
Application Deadline: 31 March 2020

Funding Type

PhD Type

Myeloproliferative neoplasms (MPNs) are a group of three related blood cancers in which the bone marrow overproduces one of the three cellular components of blood (erythrocytes, leukocytes and platelets).
  Targeting chronic inflammation to improve vein graft function following bypass surgery.
  Prof Tim Palmer, Prof M Loubani
Applications accepted all year round

Funding Type

PhD Type

Targeting chronic inflammation to improve vein graft function following bypass surgery. Coronary heart disease (CHD) causes over 66,000 deaths/year in the UK.
  The Role of CCR5 in Embryo Development
  Dr R Sturmey
Applications accepted all year round

Funding Type

PhD Type

Chemokines are small peptides that play key roles in cell migration and signalling. They act primarily by binding specific cell surface receptors to drive intracellular signalling and are key mediators of the immune response.
  Fully-funded North West Cancer Research (NWCR) Centre PhD Studentship

Funding Type

PhD Type

The NWCR Centre comprises a network of research groups from across the north west of England who work on basic and translational aspects of cancer biology and treatment.
  Applying human drug discovery approaches to kauri die back disease
  Prof M Glass
Applications accepted all year round

Funding Type

PhD Type

Phytophthora agathidicida is currently threatening New Zealand’s most iconic tree, the kauri. Current efforts to halt its spread through New Zealand forests are failing.
  Cardiac energetics and integrative physiology: Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Prof C Lygate, Dr S Zervou
Application Deadline: 10 January 2020

Funding Type

PhD Type

Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 10 January 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Myocardial biology with a specific focus on the mechanisms underlying cardiac fibrosis and atrial fibrillation
  Dr S Reilly, Prof C Redwood, Assoc Prof M Lei
Application Deadline: 10 January 2020

Funding Type

PhD Type

Cardiac fibrosis is a hallmark histological feature of structural changes in the myocardium associated with virtually all cardiac diseases (e.g., heart failure, hypertension, atrial fibrillation and myocarditis).
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 10 January 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Evolutionary Perspectives on Medicinal Plant Use
  Prof J A Hawkins
Applications accepted all year round

Funding Type

PhD Type

This project encompasses 1. evolutionary aspects of medicinal plant use and 2. authentication. You will collect DNA sequence data at the level of a whole flora and at the level of a genus.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  Novel strategies for the diagnosis and treatment of snakebites
  Dr S Vaiyapuri
Applications accepted all year round

Funding Type

PhD Type

Snakebites represent a major neglected tropical disease affecting several million people worldwide and resulting in as many as 150000 deaths each year.
  Affective Immunology: understanding the crosstalk between emotions and the immune system
  Prof F D'Acquisto
Applications accepted all year round

Funding Type

PhD Type

I am currently trying to develop a new area of research that I have christened ‘Affective Immunology’ (see this link http://www.affectiveimmunology.com for more details or this review paper https://www.dialogues-cns.org/contents-19-1/dialoguesclinneurosci-19-9/).
  BBSRC White Rose CASE studentship - Novel approaches for the identification of allosteric inhibitors of high value therapeutic targets
  Prof J P Waltho
Application Deadline: 6 January 2020

Funding Type

PhD Type

This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins.
  EASTBIO Neuroplasticity of a spinal motor circuit
  Dr W Li, Dr I Somorjai
Application Deadline: 5 January 2020

Funding Type

PhD Type

One primary function for vertebrate spinal cord is to generate commands to control rhythmic locomotion like walking, swimming or running.
  MASTERS BY RESEARCH PROJECT: Maturing stem cell-derived cardiomyocytes to provide improved models of arrhythmia
  Dr S Harmer, Prof J C Hancox
Applications accepted all year round

Funding Type

PhD Type

Start 23 September 2019. This MSc by Research is a laboratory-based project which offers the exciting opportunity to spend 1 year in one of our State-of-the-Art laboratories (plus 1 year thesis writing) at the University of Bristol and experience life as a researcher.
  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
  Climate Change Solutions: Developmental Programming of Fish Thermal Tolerance Limits
  Dr G Galli, Dr H Shiels
Applications accepted all year round

Funding Type

PhD Type

Climate change poses a significant threat to global biodiversity. Conservation strategies are critically dependent on a thorough understanding of the effects of fluctuating environments on animal morphology, physiology and behaviour.
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