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We have 97 pharmacology PhD Projects, Programmes & Scholarships

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pharmacology PhD Projects, Programmes & Scholarships

We have 97 pharmacology PhD Projects, Programmes & Scholarships

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Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more
 Supervisor: Dr T Nasim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more
 Supervisors: Dr R Wheelhouse, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of a personalized therapy for pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
 Supervisor: Dr T Nasim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Psychedelic drugs and serotonergic modulation of functional connectivity in neuronal microcircuits

University of Nottingham School of Life Sciences
Psychoactive drugs result in profound alterations of our state of consciousness. Well known examples of such drugs are general anaesthetics, in use since mid-19th century, and psychedelics, which are consumed by different societies from times immemorial. Read more
 Supervisor: Dr MO Okun
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PBPK modelling of disease-drug interactions using transporter and enzyme biomarker data

The University of Manchester Faculty of Biology, Medicine and Health
Precision dosing strategies require accounting for between-patient variability in pharmacokinetics. Read more
 Supervisors: Dr A Galetin, Dr Daniel Scotcher, Prof A Rostami
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of Human cytomegalovirus glycoprotein polymorphisms in disease pathogenesis

The University of Manchester Faculty of Biology, Medicine and Health
Human cytomegalovirus (HCMV) produces asymptomatic infection in most immunocompetent individuals but thereafter establishes life-long infection with periodic reactivation and asymptomatic shedding. Read more
 Supervisors: Prof P Vallely, Prof P Klapper
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Discerning the role of metabolic proteins in nucleus

The University of Manchester Faculty of Biology, Medicine and Health
Pancreatic Ductal Adenocarcinoma (PDAC), which develops from cells lining pancreas ducts, represents 95% of all pancreatic cancer cases. Read more
 Supervisor: Dr A Latif
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the risk of biguanides and statins on cancer incidence and mortality rates: a mixed methods study combining pharmacoepidemiological and experimental approaches

The University of Manchester Faculty of Biology, Medicine and Health
In the UK, every two minutes someone is diagnosed with cancer and every four minutes someone dies from it– leading to more than 360,000 new cases and 160,000 deaths annually1. Read more
 Supervisor: Dr A Latif
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health
A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
 Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Tackling health inequity in pharmaceuticals

University College London UCL School of Pharmacy
Tackling health inequity in pharmaceuticals. Research has been increasingly highlighting the disparities in the investigation of gender-specific responses to medicines. Read more
 Supervisor: Prof A Basit
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more
 Supervisor: Dr T You
 1 August 2024  PhD Research Project  Self-Funded PhD Students Only
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Network-based predictive modelling of cardiovascular disease risk

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more
 Supervisor: Dr T You
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring the molecular mechanisms of skin aging process and understanding the relationship between skin aging and systemic aging

University of Nottingham School of Pharmacy
Applicants are invited for fully funded 3 years full time PhD studentships, starting from 1st February 2023, or 1st April 2023, or 1st October 2023 at latest, based in the School of Pharmacy, The University of Nottingham. Read more
 Supervisor: Dr Z Zhu
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Targeting the sweet tooth to curb population-wide sugar intake

University of Nottingham School of Medicine
Excess intake of dietary sugars are a major contributor to obesity, and type 2 diabetes and 82% of people state that taste is the major determinant of what they buy and eat. Read more
 Supervisor: Dr P Aldiss
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mechanochemical Preparation of Biodegradable Pharmaceuticals

University of Birmingham School of Chemistry
Twin-screw extrusion (TSE) has been demonstrated as an excellent means of industrialising mechanochemistry (instigation of a chemical reaction by mechanical energy, in the absence of solvents), overcoming the barriers involved in batch processing (such as ball milling) such as scalability and reaction temperature control. Read more
 Supervisor: Dr D C Crawford
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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PhD scholarship opportunity: Monash-Bath Global PhD Program in Sustainable Chemical Technologies

Monash University
Location. Clayton, Victoria, Australia. Employment Type. Full-time. Duration. Students are expected to complete their degree within 3 to 4 years equivalent full-time. Read more
 Funded PhD Programme (Students Worldwide)  Australia PhD Programme
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PhD scholarship opportunity: Monash-Bath Global PhD Program in Sustainable Chemical Technologies

University of Bath
Location. Clayton, Victoria, Australia. Employment Type. Full-time. Duration. Students are expected to complete their degree within 3 to 4 years equivalent full-time. Read more
 Funded PhD Programme (Students Worldwide)  Australia PhD Programme
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Interaction between innate immune activation and endothelial cells, linked to adverse cardiovascular events

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The complement system is a key component of the immune response. Maintaining a balance between activation and inhibition of the complement system is key to preserving tissue homeostasis and enabling immune surveillance. Read more
 Supervisors: Dr N Liptrott, Dr R Rainbow, Prof C Dart
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Circadian Rhythms and Ageing

University of Greenwich School of Pharmacy (Medway Campus)
About the Project. We are pleased to offer the opportunity for a self-funded PhD student to join our research team within the School of Pharmacy, University of Kent. The research aims of this project are to explore the impact of Aging on the mammalian circadian clock. Read more
 Supervisors: Dr G Lall, Dr AS Steponenaite
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Circadian Rhythms and Ageing

University of Kent Medway School of Pharmacy
About the Project. We are pleased to offer the opportunity for a self-funded PhD student to join our research team within the School of Pharmacy, University of Kent. The research aims of this project are to explore the impact of Aging on the mammalian circadian clock. Read more
 Supervisors: Dr G Lall, Dr AS Steponenaite
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanism of vimentin induced epithelial mesenchymal transition (EMT) and stemness in cancer cells

Queen Mary University of London Institute of Dentistry
Background. Most cancers are epithelial in origin and arise from a single progenitor cell, similar to an embryo, to become a clone of cells. Read more
 Supervisors: Prof A Waseem, Dr H Tummala, Dr F Flores-Borja
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry
Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more
 Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Transcriptome biomarkers and mechanisms of chemoresistance

Queen Mary University of London Institute of Dentistry
Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more
 Supervisor: Dr M T Teh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterisation of a novel transporter for the atypical antipsychotic clozapine

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Schizophrenia is a severe psychiatric illness affecting about 24 million people worldwide. Schizophrenia can have a devastating effect on a patient’s life and is associated with increased mortality, with life expectancy reduced on average by 15 years compared to that of the general population. Read more
 Supervisors: Dr D Dickens, Prof M Pirmohamed
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain

University of Nottingham School of Life Sciences
Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more
 Supervisor: Dr G Sheridan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Novel strategies for the diagnosis and treatment of snakebites

University of Reading School of Pharmacy
Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more
 Supervisor: Prof SV Vaiyapuri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

University of Reading School of Pharmacy
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more
 Supervisor: Prof D Widera
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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