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We have 52 protein production PhD Projects, Programmes & Scholarships

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protein production PhD Projects, Programmes & Scholarships

We have 52 protein production PhD Projects, Programmes & Scholarships

Obtaining insights into how a signalling hub protein Ras activates multiple effectors

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Molecular level understanding of Mycobacterium tuberculosis

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more

Understanding the role of spliceosome gene mutations in disease

The DNA of a cell is copied into a pre-messenger RNA (pre-mRNA) that the cell uses as a template for protein production. Some of the information contained in DNA is not required for making proteins, therefore, unwanted information must be removed before a protein is made. Read more

Glycosylation in Microalgal Host Cells

Microalgae have generated increasing interest as microbial cell factories to produce therapeutics proteins. This is because they can grow on very cheap media and their GRAS (generally regarded as safe) status means they are a fantastic option for the production of therapeutics that can be administered orally. Read more

Development of integrated microfluidic chips for making mRNA nanomedicines

Project. Messenger RNA (mRNA) provides a highly flexible platform for the development of vaccines. A robust immune response typically requires both an antibody response and a T-cell response. Read more

Regulation of protein palmitoylation in the heart by persulphidation

Hydrogen sulphide (H2S) is known to have cardioprotective qualities. Persulphidation is a reversible post-translational modification (PTM) in which a persulphide group is formed by the reaction of H2S with the thiol groups of cysteine residues in proteins. Read more

AI-Enhanced Self-Updating Digital Twin for Optimised Spray Drying in Dairy Manufacturing

The Postgraduate Research Programme MedAgriTech AI eXcellence (MATX) offers 12 PhD research scholarships to commence in 2024. Each project will include an enterprise placement of minimum 12 weeks duration. Read more

Effect of androgens on preantral follicle development

Polycystic ovary syndrome (PCOS) is a condition that affects >5% of women of reproductive age and is the most common cause of menstrual dysfunction and is associated with metabolic abnormalities and increased risk to long-term health. Read more

Unlocking immune cells with tick-borne pathogens

In this project we will use tick-borne pathogenic bacteria as a molecular tool-kit for unlocking immune cells. These discoveries will help us combat tick-borne disease and provide a basis for manipulating immune cells, impacting on a wide range of diseases. Read more

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