receptor PhD Projects, Programmes & Scholarships

Mechanistic insights into Family B G-protein-coupled receptors (GPCRs) using SMA-like polymers

Coventry University Centre for Health and Life Sciences

Calcitonin receptor-like receptor (CLR) is an important family B G-protein-coupled receptor (GPCR) that is significantly under-explored, despite huge therapeutic potential. Read more

Supervisor: Dr H A Ayub

27 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating the interactions of incretin hormone mimetics with hypothalamo-neurohypophysial system arginine vasopressin and oxytocin release

University of Bristol Bristol Medical School

Our research focus over decades has been the osmoregulatory function of a special collection of neurones in a part of the brain called the hypothalamus. Read more

Supervisor: Prof D Murphy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Aberrant bone morphogenetic protein signalling in precision medicine of targeting tyrosine receptor kinase in solid tumours

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£55,000 total). Read more

Supervisor: Dr L Ye

31 May 2024 PhD Research Project Self-Funded PhD Students Only

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Diabetes and Breast Cancer from the perspective of oestrogen receptor expression

Sheffield Hallam University Biomolecular Sciences Research Centre

The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more

Supervisors: Dr SA Ahmed, Dr NP Peake, Dr DK Kelly

10 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Use of a novel conjugation approach to generate a long-acting growth hormone receptor antagonist

University of Auckland Liggins Institute

Targeting the growth hormone (GH) signalling pathway could be an effective therapeutic approach for certain types of cancer. However, a lack of access to therapeutics that target GH or the GH receptor has hindered preclinical studies in this field. Read more

Supervisors: Dr Y Wang, Dr J Perry

30 August 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular characterisation of scavenger receptor ligand binding.

University of Sheffield School of Biosciences

Scavenger receptors have been identified as being important in Human disease and normal physiological responses. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously. Read more

Supervisors: Dr S Brown, Dr I Evans

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Regulation of microglial phenotypes by adenosine and in contribution to ageing in the brain

University of Dundee School of Life Sciences

Microglia are the major innate immune cells in the central nervous system and are required for the response to invading pathogens, removal of damaged or… Read more

Supervisors: Prof S Arthur, Dr A Lloyd

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating platelet signalling and thrombus formation

University of Birmingham Institute of Cardiovascular Sciences

We are seeking talented, motivated students with a passion for research in cardiovascular cell biology to work in the group of Dr Natalie Poulter, which focuses on understanding how platelets become activated and form a thrombus. Read more

Supervisor: Dr N Poulter

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and mechanistic studies of fibroblast growth factor receptor signalling

University of Leeds Faculty of Biological Sciences

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Prof A.L. Breeze, Prof F. Sobott

Year round applications PhD Research Project Self-Funded PhD Students Only

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SLS SF2: Targeting the pro-resolving receptor Fpr2 for the treatment of osteoarthritis

University of Westminster School of Life Sciences

Osteoarthritis is a degenerative disease being a major contributor to long-term disability, leading to increased morbidity and social isolation within groups of individuals over 65 years of age. Read more

Supervisors: Dr S Getting, Dr KP Cunningham, Dr IL Locke, Dr M Ashioti

17 May 2024 PhD Research Project Self-Funded PhD Students Only

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Determine the efficacy of growth hormone receptor antagonism in hepatocellular carcinoma spheroid culture models

University of Auckland Liggins Institute

Hepatocellular carcinoma (HCC) is an aggressive and difficult to treat cancer with poor survival rates and limited systemic treatment options for advanced-stage disease. Read more

Supervisors: Dr Y Wang, Dr J Perry

28 February 2025 PhD Research Project Self-Funded PhD Students Only

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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Supervisor: Dr M Soller

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Preventing Prostate Cancer, and Related Metastases

Medical University of Vienna Institute for Pathophysiologie and Allergy

The goal of this project is to elucidate the role of the thyroid hormone pathway for prognosis and therapy response of prostate cancer (PCa). Read more

Supervisor: Dr L Kenner

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Preformulation study of RARγ and VDR hybrid compounds

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) will perform preformulation characterisation and development of formulation prototypes at Trinity College Dublin (TCD), Ireland. Read more

Supervisor: Assoc Prof LT Tajber

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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In silico modelling of endocannabinoid evolution

University of Worcester Research School

In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more

Supervisor: Dr M Di Micelli

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

University of Reading School of Pharmacy

Are you ready to delve into the captivating world of molecular signaling and unravel the mysteries of the cardiovascular and nervous systems? We are thrilled to offer an exhilarating PhD opportunity at the forefront of scientific exploration. Read more

Supervisors: Dr G Cottrell, Prof D Widera, Dr S Amadesi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways

University of Cambridge Department of Biochemistry

Our research aims to elucidate the molecular and cellular regulation of innate immune signal transduction in the context of infectious, inflammatory and autoimmune disease. Read more

Supervisor: Prof N J Gay

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Genomic actions of RAR and VDR ligands

Medical University of Vienna Institute for Pathophysiologie and Allergy

The Doctoral Candidate (DC) will determine whether the combination of RARγ antagonist and VDR agonist is suitable as a differentiation therapy against acute myeloid leukaemia (AML). Read more

Supervisor: Prof E Marcinkowska

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Treatment of Breast Cancer and Preventing Relapse

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) The DC will perform biological basic research on cancer in vitro and in vivo at the CIMUS-University of Santiago de Compostela (Spain). Read more

Supervisor: Prof RPF Pérez-Fernández

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Preventing Ovarian Cancer, Colorectal Cancer, and Related Metastases

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) will perform basic molecular biology research on in vitro and in vivo cancer models at the Medical University of Vienna, Austria. Read more

Supervisors: Dr MSch Schepelmann, Prof E K Kallay

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Sensitizing AML cells to RAR and VDR ligands (vitamin A and D derivatives) to prevent leukaemia relapse

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) will perform basic research on leukaemia cell biology in vitro and in vivo at the Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel. Read more

Supervisor: Dr MD Danilenko

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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The selective action of RAR ligands

University of Birmingham Institute of Cancer and Genomic Sciences

The cells that sustain a cancer and that are largely responsible for metastatic and aggressive disease are termed cancer stem cells. Read more

Supervisors: Dr M Hoogenkamp, Prof G Brown

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

Kingston University Faculty of Health, Science, Social Care and Education

Cancer is a disease that is rapidly increasing. The initiation and progression of cancer is a central topic of countless research with discoveries of multiple pathways implicated in formation and advancement of this debilitating disease. Read more

Supervisor: Dr A Elbediwy

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Design and synthesis of chemical tools to interrogate cannabinoid receptors - synthetic, medicinal chemistry

University of Otago Department of Chemistry

Research project. We are seeking a highly motivated PhD candidate to join an interdisciplinary team at the University of Otago, to undertake research developing chemical probes for the cannabinoid receptor, a type of G protein-coupled receptor (GPCR). Read more

Supervisor: Dr AJ Vernall

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Targeting the sweet tooth to curb population-wide sugar intake

University of Nottingham School of Medicine

Excess intake of dietary sugars are a major contributor to obesity, and type 2 diabetes and 82% of people state that taste is the major determinant of what they buy and eat. Read more

Supervisor: Dr P Aldiss

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the roles that G protein coupled receptors play in hypertension

University of Leicester Molecular and Cell Biology

G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more

Supervisor: Dr J Willets

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring the role of tryptophan metabolism in schizophrenia pathogenesis

University of Leicester Department of Genetics and Genome Biology

L-kynurenine (KYN) and kynurenic acid (KYNA) are metabolites of the kynurenine pathway (KP) of tryptophan degradation and have been found to be increased in the brains of patients with schizophrenia. Read more

Supervisor: Prof F Giorgini

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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We have 78 receptor PhD Projects, Programmes & Scholarships

receptor PhD Projects, Programmes & Scholarships

We have 78 receptor PhD Projects, Programmes & Scholarships

Mechanistic insights into Family B G-protein-coupled receptors (GPCRs) using SMA-like polymers

Investigating the interactions of incretin hormone mimetics with hypothalamo-neurohypophysial system arginine vasopressin and oxytocin release

Aberrant bone morphogenetic protein signalling in precision medicine of targeting tyrosine receptor kinase in solid tumours

Diabetes and Breast Cancer from the perspective of oestrogen receptor expression

Use of a novel conjugation approach to generate a long-acting growth hormone receptor antagonist

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Molecular characterisation of scavenger receptor ligand binding.

MSc by Research: Regulation of microglial phenotypes by adenosine and in contribution to ageing in the brain

Investigating platelet signalling and thrombus formation

Structural and mechanistic studies of fibroblast growth factor receptor signalling

SLS SF2: Targeting the pro-resolving receptor Fpr2 for the treatment of osteoarthritis

Determine the efficacy of growth hormone receptor antagonism in hepatocellular carcinoma spheroid culture models

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

Preventing Prostate Cancer, and Related Metastases

Preformulation study of RARγ and VDR hybrid compounds

In silico modelling of endocannabinoid evolution

Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways

Genomic actions of RAR and VDR ligands

Treatment of Breast Cancer and Preventing Relapse

Preventing Ovarian Cancer, Colorectal Cancer, and Related Metastases

Sensitizing AML cells to RAR and VDR ligands (vitamin A and D derivatives) to prevent leukaemia relapse

The selective action of RAR ligands

Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

Design and synthesis of chemical tools to interrogate cannabinoid receptors - synthetic, medicinal chemistry

Targeting the sweet tooth to curb population-wide sugar intake

Investigating the roles that G protein coupled receptors play in hypertension

Exploring the role of tryptophan metabolism in schizophrenia pathogenesis

We have 78 receptor PhD Projects, Programmes & Scholarships

receptor PhD Projects, Programmes & Scholarships

We have 78 receptor PhD Projects, Programmes & Scholarships

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