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rnai PhD Projects, Programs & Scholarships

We have 19 rnai PhD Projects, Programs & Scholarships

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Showing 1 to 19 of 19
  RNAi as a pest management tool in Aphids
  Dr T Davies, Dr S Foster
Application Deadline: 1 December 2019

Funding Type

PhD Type

An exciting opportunity for a 3-year AHDB-funded PhD on ‘targeted gene silencing’ to control aphid infestations in UK cereals and oilseeds.
  Functional analysis of fungal effector proteins in the barley/wheat powdery mildew plant-pathogen interactions.
  Dr L Bindschedler, Prof A Devoto
Applications accepted all year round

Funding Type

PhD Type

Pathogens secrete small proteins called effectors or virulence factors which are important for the successful invasion of the host.
  Deciphering a novel anti-ageing epigenetic programme
  Dr G Poulin, Prof A Sharrocks
Applications accepted all year round

Funding Type

PhD Type

Over two decades of intense research in the field of epigenetics have produced compelling evidence that chromatin modifications are crucial for processes such as DNA repair, transcription, splicing, mitosis, meiosis, and in the preservation of the epigenetic memory of cells.
  Understanding regulation of gene expression during development via an integrated computational analysis of ‘omics data
  Prof S Hubbard, Prof S Griffiths-Jones, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Embryonic development requires exquisite control of the expression of large numbers of genes, integrating components from the genome, transcriptome and proteome.
  Intronic gene silencing: new mechanism of gene expression regulation and its relevance to cancer
  Dr M Gullerova
Application Deadline: 10 January 2020

Funding Type

PhD Type

Mammalian cells employ small RNAs (sRNAs) molecules to regulate gene expression in a pathway known as RNA interference (RNAi). Transfer RNAs (tRNAs) are essential for translation but also serve as a source for tRNA-derived small RNAs (tsRNAs).
  Nanoparticles in drug delivery
  Dr G Stenbeck, Dr U Kishore
Applications accepted all year round

Funding Type

PhD Type

Nanoparticles (NPs) are materials with overall dimensions in the nano scale range (5nm-100nm). Due to their unique physicochemical properties, they have found a wide range of applications and are currently explored as drug and gene delivery vehicles.
  Transcription control and immune evasion in African trypanosomes
  Research Group: Division of Cell & Molecular Biology
  Prof G Rudenko
Applications accepted all year round

Funding Type

PhD Type

Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  The role of long noncoding RNAs in cell division and genome stability
  Dr L Stojic, Dr S McClelland
Application Deadline: 15 November 2019

Funding Type

PhD Type

Our group studies the biology of long noncoding RNAs (lncRNAs) and their roles in cell division and maintenance of genome stability.
  Investigating the Drosophila DF31 protein to gain insight into the mechanisms and chromatin maintenance in animal cells
  Dr S Cotterill, Dr A Nohturfft
Applications accepted all year round

Funding Type

PhD Type

The Drosophila DF31 protein is an abundant ribonucleoprotein that localises to euchromatic regions and is involved in maintaining chromosome structure.
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  Microtubule motors in cell migration and integrin trafficking
  Prof V Allan, Prof P Woodman, Dr P Caswell
Applications accepted all year round

Funding Type

PhD Type

Cell migration is vital for the development and health of multicellular organisms. However, enhanced cell migration is also a hallmark of cancer cells, and contributes greatly to metastasis.
  Preparing the acid bath: how epidermal growth factor receptor (EGFR) controls its own down-regulation
  Prof P Woodman, Dr C Francavilla
Applications accepted all year round

Funding Type

PhD Type

Signalling by cell surface receptors determines nearly every aspect of the cell’s response to its environment. Endosomes are hubs for regulating these signalling pathways.
  Stress regulation of protein translation: role in cancer and neurodegeneration
  Dr A J Whitmarsh, Prof M Ashe
Applications accepted all year round

Funding Type

PhD Type

Cells are subjected to a range of stresses that include physical injury, changes in oxygen levels or temperature, nutrient deprivation, radiation and infection.
  The functions of the Class II Pi3-kinase signals in vivo
  Dr L MacDougall, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Phosphoinositide lipids (PIPs) play critical roles in development and the homeostasis of adult tissues and their dysfunction has been linked to major human diseases such as cancer, diabetes, myopathies and neuropathies.
  Investigating the role of lysine methylation in the DNA damage response.
  Dr M Higgs
Applications accepted all year round

Funding Type

PhD Type

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including haematopoietic abnormalities and developmental disorders as well as cancer.
  Non-coding RNA regulation of stem cells
  Dr S Brown, Dr P Gokhale
Applications accepted all year round

Funding Type

PhD Type

Stem cells have the potential to make any cell type in the Human body and are powerful tools in drug discovery (Xia and Wong, 2012).
  Syndecan-4 regulates cell migration during healing and cancer through caveolar endocytosis
  Dr M Bass
Applications accepted all year round

Funding Type

PhD Type

Cell migration during wound healing or cancer cell invasion involves responses to multiple factors including extracellular matrix and growth factors.
  Ion channel signalling in cancer cells
  Dr W Brackenbury
Application Deadline: 30 June 2020

Funding Type

PhD Type

Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing.
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