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structural biology PhD Projects, Programs & Scholarships

We have 252 structural biology PhD Projects, Programs & Scholarships

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  Dynamic Structural Biology Studentship (stipend £2,000 above the standard UKRI rate)
  Prof E Raven, Dr A Orville, Prof P Moody
Application Deadline: 15 March 2020

Funding Type

PhD Type

Applications are invited for a studentship in dynamic structural biology starting in October 2020 to be jointly supervised by Dr Allen M.
  Harnessing Computational and Structural Biology Platforms for Drug Discovery
  Dr D Cole, Dr N Tatum, Dr E Pohl
Application Deadline: 6 March 2020

Funding Type

PhD Type

The spread of low-cost computing and development of data analysis techniques, such as machine learning, promise to improve our understanding of biological disease mechanisms and the design and prioritisation of new pharmaceutical molecules.
  PhD in Structural biology/Protein biochemistry – The role of protein amyloid fibrils in disease
  Dr V Morris
Application Deadline: 14 March 2020

Funding Type

PhD Type

The Morris lab at the University of Canterbury, New Zealand, is seeking a motivated student to carry out investigations of protein aggregation.
  Developing H/D-exchange mass spectrometry for native membrane protein structural biology
  Dr E Reading
Application Deadline: 12 April 2020

Funding Type

PhD Type

Supervisors. Dr. Eamonn Reading (Primary supervisor – KCL), Mr. Malcolm Anderson (Industrial supervisor - Waters Corporation), Prof.
  PhD in cellular and structural biology - Elucidating infection at the plant-microbe interphase to define targets for crop breeding
  Dr C Voigt
Applications accepted all year round

Funding Type

PhD Type

Achieving food security is one of the most important global challenges. Crop production and yield has been increasingly threatened by plant pathogens in a rapidly changing environment.
  Structural biology of the intrinsically disordered protein SH2B1
  Prof M P Williamson
Applications accepted all year round

Funding Type

PhD Type

Signalling between the outside of the cell and the inside uses a complicated network of interacting systems. One common signalling mechanism uses receptor tyrosine kinases.
  Modular design of custom protein structures
  Dr F Parmeggiani
Applications accepted all year round

Funding Type

PhD Type

Proteins perform most of the functions in biological systems, from structural support, to movement, communication and catalysis. Our goal is to use modular building blocks to quickly and precisely design novel protein nanomaterials and nanoparticles to control cell behaviour.
  Myocardial biology with a specific focus on the mechanisms underlying cardiac fibrosis and atrial fibrillation
  Dr S Reilly, Prof C Redwood, Assoc Prof M Lei
Application Deadline: 24 July 2020

Funding Type

PhD Type

Cardiac fibrosis is a hallmark histological feature of structural changes in the myocardium associated with virtually all cardiac diseases (e.g., heart failure, hypertension, atrial fibrillation and myocarditis).
  Understanding the mechanism of RNA recognition by La-related proteins
  Prof MR Conte
Applications accepted all year round

Funding Type

PhD Type

A PhD studentship is available to work in the laboratory of Prof. Sasi (Maria R) Conte (https://www.kcl.ac.uk/people/sasi-conte), in the Randall Centre for Cell and Molecular Biophysics, King’s College London (https://www.kcl.ac.uk/lsm/research/divisions/randall).
  Enzyme mechanism through advanced techniques
  Dr P C E Moody
Applications accepted all year round

Funding Type

PhD Type

This studentship is for up to 4 years and supported by a Royal Society Wolfson Fellowship. “Traditional” protein X-ray crystallography has contributed enormously to our understanding of enzyme mechanisms.
  EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships

Funding Type

PhD Type

Recruitment for the next cohort of studentships commencing in September 2020 will open in early 2020.
  EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships

Funding Type

PhD Type

Recruitment for the next cohort of studentships commencing in September 2020 will open in early 2020.
  Ion channel clustering in neuronal membranes
  Dr S M Prince, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions.
  The mechanism of gating and transport of pentameric Magnesium ion channels
  Dr S M Prince, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

Magnesium ions are a co-factor in many important biological processes particularly because of the requirement for Mg2+ in the hydrolysis of Adenosine tri-phosphate, the ubiquitous cellular energy source.
  Development of Novel Crystallization Methods for Integral Membrane Proteins
  Dr G Patchornik
Applications accepted all year round

Funding Type

PhD Type

Our research is focused on one of the major barriers in Structural biology. growing high quality three dimensional (3D) crystals of integral membrane proteins for structural analysis.
  Baculovirus P10 and microtubules; the role of P10 in virus-induced nuclear lysis with possible applications for novel anti-cancer therapies
  Prof L A King, Dr V Bolanos-Garcia
Application Deadline: 20 March 2020

Funding Type

PhD Type

Oxford Brookes University. Faculty of Health and Life Sciences,. Department of Biological and Medical Sciences. 3.5 year, full-time PhD iCASE studentship.
  PhD Position in Cryo Electron Microscopy of Rhodopsin Cyclases
  Prof P Wendler
Applications accepted all year round

Funding Type

PhD Type

Eukaryotic rhodopsin guanylyl cyclases (RhGC) and rhodopsin phosphodiesterases (RhPDE) combine a rhodopsin photoreceptor module with an enzymatic unit that catalyzes the conversion of cyclic nucleotides to the corresponding 5’-phosphate nucleotide or vice versa.
  Bioengineering of bacterial CO2-concentrating system for improved photosynthesis
  Prof LN Liu, Dr D Canniffe
Applications accepted all year round

Funding Type

PhD Type

The single-cell photosynthetic bacteria, cyanobacteria, account for over 25% of global carbon fixation, thanks for their powerful CO2-concentrating machinery.
  Establishing NMR chemical shifts as reliable reporters of atomic charge distributions in enzymes
  Prof J Waltho, Prof P Popelier
Applications accepted all year round

Funding Type

PhD Type

Enzymes are not only central to life but also to the growing need to harness elements of the natural world to the benefit of mankind.
  Control and inhibition of virus replication
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A.K Tuplin
Applications accepted all year round

Funding Type

PhD Type


The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specificaly Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.
  PhD in Chemical Biology -- Neuropeptide Research -- University of Vienna
  Prof M Muttenthaler
Applications accepted all year round

Funding Type

PhD Type

Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Application Deadline: 1 April 2020

Funding Type

PhD Type

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas.
  Fostering development of ‘smart’, responsive therapeutics against cancer-related microRNAs.
  Dr E Bichenkova, Prof D Clarke, Dr H Aojula
Applications accepted all year round

Funding Type

PhD Type

Short functional non-coding microRNAs are implicated in many types of cancer, and thus can be used as biological targets for development of more selective and powerful anticancer therapies.
  Mitochondrial protein folding and diseases
  Prof L-Y Lian, Dr D Criddle
Applications accepted all year round

Funding Type

PhD Type

Many diseases, including cancer and neurological disease, stem from mitochondrial dysfunctions often triggered by sudden elevation of agents such as calcium and reactive oxygen species.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  Development of chemical biology tools to study mammalian O-mannosylation pathways
  Dr L Willems, Prof G Davies
Applications accepted all year round

Funding Type

PhD Type

The field of chemical biology aims to design and synthesize chemical tools (such as inhibitors, substrate mimics, or enzyme probes) to answer fundamental questions in biology.
  CRISPR Screen Multiplexing for Uncharacterised Region Function (SMURF)
  Dr L Prendergast, Dr M Martin, Prof S Wedge
Application Deadline: 6 March 2020

Funding Type

PhD Type

CRISPR-Cas9 screening utilising tiling-sgRNA design across genes, permits functional evaluation of protein domains and precise mapping of critical amino acids.
  PhD position - Structural basis of melanogenesis enzymes
  Dr M Soler-Lopez
Applications accepted all year round

Funding Type

PhD Type

Ref. InnovaXN_17_ESRF. Categorisation. Places of work. - Grenoble, Rhône-Alpes, France. Contract type. Contract, start on 2020-09-07.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round

Funding Type

PhD Type

In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
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