Imperial College London Featured PhD Programmes
Sheffield Hallam University Featured PhD Programmes
Life Science Zurich Graduate School Featured PhD Programmes
"t" AND "cell"×
10 miles

t cell PhD Projects, Programs & Scholarships

We have 92 t cell PhD Projects, Programs & Scholarships

  • "t" AND "cell" ×
  • clear all
Order by 
Showing 1 to 30 of 92
  How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function
  Dr K Couper, Prof R K Grencis
Applications accepted all year round

Funding Type

PhD Type

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state.
  Rhythms under your skin: Enhancing vaccine efficiency using a state-of-the-art dissolvable intradermal microneedle patch and harnessing the skin dendritic cell circadian clock
  Dr A Curtis, Dr R Donnelly
Applications accepted all year round

Funding Type

PhD Type

Vaccination is the greatest success story of modern medicine with the WHO estimating 10 million deaths were prevented by vaccines between 2010 and 2015.
  Identification of key determinants affecting the quality of human Cancer specific cytotoxic T cells
  Prof T Dong
Application Deadline: 24 July 2020

Funding Type

PhD Type

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting Cytotoxic T cells in controlling cancer development.
  Identification of key determinants affecting the quality of human Cancer specific cytotoxic T cells
  Prof T Dong
Application Deadline: 24 July 2020

Funding Type

PhD Type

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting Cytotoxic T cells in controlling cancer development.
  Expanded potential stem cells for regenerative medicine, immunotherapy, and biotechnology
  Prof P Liu
Applications accepted all year round

Funding Type

PhD Type

Embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells) are pluripotent and thus hold great promise in regenerative medicine, studying disease mechanisms and drug discovery.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  Using T cells to eradicate cancer
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in immuno-oncology and the development of novel immunotherapeutic approaches for the treatment of cancer.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Investigation of a completely uncharacterised, embryonically lethal gene in immune cell development
  Dr J James, Prof K Sampath
Application Deadline: 7 June 2020

Funding Type

PhD Type

The development of vertebrate animals from a single fertilised cell to the fully formed adult is an astonishingly well-choreographed sequence of events, which is made more remarkable by being so faithfully recapitulated on each attempt.
  Exploiting tumour-promoting paracrine signals in solid cancers to turbocharge genetically redirected T cells
  Dr A Hurlstone, Prof R Edmondson
Applications accepted all year round

Funding Type

PhD Type

Adoptive cell therapy (ACT) using tumour infiltrating lymphocytes (TILs) or genetically redirected T cells are some of the most promising approaches to emerge recently for the treatment of metastatic disease.
  Centrosome Amplification and Cancer
  Dr Y Ching
Applications accepted all year round

Funding Type

PhD Type

Centrosome, which is the microtubule-organising center (MTOC) in the cell, plays a critical role in determining the motility, polarity and division of cell.
  Regulation of host cell DNA damage response pathways by adenovirus
  Dr A S Turnell, Dr C McCabe
Applications accepted all year round

Funding Type

PhD Type

Human adenoviruses are small non-enveloped viruses with a linear, double-stranded DNA genome. Adenovirus has long served as a faithful model for dissecting the molecular basis of key cellular signalling pathways that regulate fundamental biological processes such as cell growth, cell differentiation and cell death.
  Protein complexes required for bacterial cell wall biosynthesis and division
  Prof D Roper, Dr A Crow, Dr M Jenner, Prof T R Dafforn
Application Deadline: 7 June 2020

Funding Type

PhD Type

Antimicrobial Resistance (AMR) is now widely understood to be a global healthcare emergency, exacerbated by many socio-economic factors.
  The role of pore-forming bacterial proteins in pneumonia and meningitis
  Prof T J Mitchell, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

The bacterium Streptococcus pneumoniae (the pneumococcus) is carried in the nasopharynx of most children and some adults without causing disease.
  Engineering Immune Cell Surfaces
  Prof I Gibson, Dr D Mitchell
Application Deadline: 7 June 2020

Funding Type

PhD Type

In the past decade there has been a revolution in therapeutics with protein and cell based therapies emerging to supplement traditional ‘small molecule’ drugs.
  Combined targeting of PD-L1 and NFκB pathways to reverse T-cell exhaustion and restore anti-tumour immunity in breast cancer.
  Dr A Idris
Application Deadline: 1 July 2020

Funding Type

PhD Type

The majority of deaths from breast cancer following conventional therapies are a result of metastases. Programmed death 1 ligand (PD-L1), a negative regulator of the immune system, is highly expressed in triple negative breast tumours and cell lines, and its expression is associated with suppressed anti-tumour immunity.
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  The Eco-Immunology of Wild Mice
  Prof M Viney
Applications accepted all year round

Funding Type

PhD Type

The immune responses that wild animals make contribute to their fitness, but what those immune responses are – and how they differ from those of laboratory animals – is hardly known.
  Proteomic analyses of adhesion signalling in cancer
  Prof M J Humphries
Applications accepted all year round

Funding Type

PhD Type

Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation.
  Epigenetics and Cancer: Development of Novel Tools to Determine how Aberrant V(D)J Recombination Reactions Cause Leukaemia
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Applications accepted all year round

Funding Type

PhD Type

V(D)J recombination generates a highly diverse set of immunoglobulin and T cell receptor genes to enable vertebrates to fight a vast range of infections.
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  The spleen as a site of relapse for early T-cell progenitor leukaemia
  Dr T Chonghaile, Prof J Prehn
Applications accepted all year round

Funding Type

PhD Type

Early T-cell progenitor ALL (ETP-ALL) originates from a block at early stages of T-cell development, has a poor prognosis with risk for relapse.
  Accelerating our ability to understand and target complexity and heterogeneity in cancer through automated imaging of 3D cancer models including patient derived organoids
  Dr C Dunsby, Prof P French
Application Deadline: 31 August 2020

Funding Type

PhD Type

Drug resistance is a major challenge for cancer therapy, arising from heterogeneous cellular behaviours within tumours, where initially identical clonal cells can mutate and adapt to diverse microenvironments.
  Adrenomedullin-2 receptor antagonists in T-cell lymphoma
  Dr G Richards, Prof T Skerry
Applications accepted all year round

Funding Type

PhD Type

Cancer cells rely upon communication between themselves and to the host tissues to survive and grow. One hormone involved in cancer signalling is adrenomedullin (AM), which also has important physiological roles in the control of blood pressure.
  Bioengineering of patient-derived explants (PDEs) and 3D organoid culture systems for tissue regeneration, cancer and drug discovery
  Dr A Shams Nateri
Applications accepted all year round

Funding Type

PhD Type

The intestine provides an attractive route to model biologically important intestinal processes and a unique opportunity for the direct identification and analysis of factors that contribute to development and maintenance of both normal as well as the development of neoplasia.
  Gene Regulatory Networks in Development and Disease
  Dr T Sauka-Spengler
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory focuses on deciphering gene regulatory networks that govern complex programmes during early vertebrate development.
  Gene Regulatory Networks in Development and Disease
  Dr T Sauka-Spengler
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory focuses on deciphering gene regulatory networks that govern complex programmes during early vertebrate development.
  Development of Raman probes for live cell tracking
  Prof A N Hulme
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for an EPSRC/GSK-funded collaborative PhD for the development and application of novel biorthogonal tagging technologies and multimodal imaging to enable tracking of multiple cell populations within complex 3D environments.
  Understanding differential responses to retinoid treatments in human health and disease: a precision medicine approach
  Prof R Watson, Dr A Langton
Applications accepted all year round

Funding Type

PhD Type

Retinoids, such as all-trans retinoic acid (t-RA), are endogenous signalling molecules derived from vitamin A that influence a variety of cellular processes through mediation of transcription events in the cell nucleus.
Show 10 15 30 per page


FindAPhD. Copyright 2005-2020
All rights reserved.