You will work on a research project with the following objectives. Generation of targeted VA causing mutations in human iPS cell lines and optimization of protocols for differentiation of targeted cells to iPS-ECs or iPS-LECs.
You will work on a research project with the following objectives. Identify novel peptides for specific targeting of lesions in mouse models of VM, LM and AVM using in vivo phage display in vitro and in vivo.
You will be part of a team of 14 ESRs working on the V.A. Cure project, which aims to uncover core mechanisms of initiation and maintenance of Vascular Anomalies with the final goal to establish novel therapeutic strategies.