1. Background to the project. Scottish people living further from key healthcare facilities have less chance of prompt cancer diagnosis and poorer cancer survival than those living closer-by[1].
Cancer immunotherapy is among the most important recent developments in cancer treatment. Despite its impressive successes, however, the response in some patients is often limited and short lived.
The cancer microenvironment contains many different cell types, including various subsets of immune cells and cancer-associated fibroblasts, which support cancer growth.
This project aims to translate, optimise and extend quantitative oxygen extraction fraction mapping based on oxygen enriched air inspiration and magnetic resonance (MR) relaxometric imaging for human application.