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  Investigating the role of the kidney in Alkaptonuria
  Prof G Bou-Gharios, Prof J A Gallagher
Application Deadline: 1 November 2019

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Alkaptonuria (AKU) is an ultrarare disease with prevalence in most populations between 1 in 250,000 to 1 in 1,000,000. AKU is a disorder of tyrosine metabolism in which degradation of tyrosine is blocked at the level of homogentisic acid due to congenital lack of homogentisate dioxygenase enzyme.
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