Post-transcriptional mechanisms greatly diversify transcriptomes and proteomes and play critical roles in fundamental biological processes associated with normal physiology, human diseases and disorders.
Q fever is an infection by the intracellular pathogen Coxiella burnetii that can cause a severe flu-like illness. The sensitive and specific diagnosis of Q fever is important for early intervention and for control and management of the disease.
Synthetic biology enables engineering of bacterial cells to serve as cell factories for the assembly of novel material such as tailor-made biopolymers attached to protein functions which mediate deposition of inorganics such as found in tooth formation.
Advances in synthetic biology allows recombinant bacteria to produce protein coated polyester particles. These polyester particles have been utilized as particulate vaccines against bacterial and viral infections.