More than 90% of human genes undergo alternative splicing, the process by which multiple, distinct transcript and protein variants are expressed from a single gene (Weatheritt et al., 2016).
Global change is predicted to result in both rapidly changing environments and dramatic changes in disease outbreaks. Key to predicting winners and losers under the nexus of infection and global change is any mismatch between hosts and pathogens in their thermal tolerances and adaptive potential.
