We have 47 Medicine PhD Projects, Programmes & Scholarships in Belfast

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Medicine

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Belfast  United Kingdom

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Medicine PhD Projects, Programmes & Scholarships in Belfast

We have 47 Medicine PhD Projects, Programmes & Scholarships in Belfast

Metagenomics to guide precision medicine in ARDS

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
Acute Respiratory Distress Syndrome (ARDS) is a severe condition characterized by acute inflammation and diffuse alveolar damage, leading to respiratory failure. Read more

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

Novel investigation of innate airways defence in Severe Asthma and elucidation of potential therapeutic targets

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
Join a distinguished translational experimental group that spans from lab work to delivery of specialist asthma clinical care, seeking to understand variation in airways immunity and how this results in varied responses to current asthma therapies. Read more

Understanding how high plasma soluble urokinase plasminogen activator receptor (suPAR) predicts poor outcome in patients with ARDS.

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
Acute Respiratory Distress Syndrome (ARDS) is a common condition in critically ill patients requiring mechanical ventilation, and is often found in association with sepsis and other systemic illnesses. ARDS is associated with a high mortality, and there are no effective pharmacological interventions. . Read more

The potential value of risk based pricing for promoting innovation in biopharmaceuticals.

  Research Group: Centre for Public Health
The prices of new pharmaceuticals have increased by orders of magnitude over the last two decades, and emerging gene therapies are expected to be priced a magnitude higher than the cellular therapies such as monoclonal antibodies. Read more

FIND-BACT Study: Finding INnovative Diagnostics for BACTerial infections in children

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
Detecting bacterial infection in children is very challenging, particularly in previously well children presenting to the Emergency department (ED) with fever as well as in children with chronic illnesses, such as those with cystic fibrosis (CF). Read more

Investigating the impact of commonly occurring blood cancer mutations on innate immune signalling

  Research Group: The Patrick G Johnston Centre for Cancer Research
Myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML) are clonal haematological malignancies that can disrupt normal haematopoiesis of multiple myeloid lineages. Read more

Investigating the role of novel and established plasma biomarkers in the evaluation of heart failure in children with heart disease

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
This project will use plasma samples of children with congenital heart disease to evaluate the role of novel and established cardiac biomarkers in identifying and monitoring paediatric heart failure. Read more

Dexamethasone-releasing cochlear implants to reduce foreign body response

Cochlear implants are surgically implanted neuroprostheses designed to produce useful hearing sensations to persons with severe-to-profound sensorineural hearing loss by electrically stimulating the auditory nerve in the inner ear (or cochlea). Read more
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Nanocrystals-in-nanofibres as a promising strategy for the delivery of poorly soluble actives

One of the most challenging issues that the pharmaceutical industry face is poor aqueous solubility of drugs. 90% of candidate molecules within the discovery pipelines face solubility issues, posing significant hurdles to their clinical translation. Read more

Microfluidic Encapsulation of biologics into Nanomedicines

Progress in drug design has led to the development of new peptides, proteins, and drug molecules. However, the limited ability to deliver selectively these molecules at well-defined dosing regimens and without invoking drug-resistance remains a significant challenge. Read more

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