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We have 78 Medicine PhD Projects, Programmes & Scholarships for Self-funded Students in Belfast
Medicine PhD Projects, Programmes & Scholarships for Self-funded Students in Belfast
We have 78 Medicine PhD Projects, Programmes & Scholarships for Self-funded Students in Belfast
Investigating new excipients to improve ionizable lipid nanoparticles’ endosomal escape and enhance gene expression
Nucleic acids have the potential to treat a wide range of diseases, from cancer to hereditary conditions. However, their clinical use has been limited due to unfavorable physicochemical properties, such as their inability to cross cell membranes and their susceptibility to degradation. Read more
Non-thermal irreversible electroporation to treat advanced cancer
Irreversible electroporation (IRE) is an innovative non-thermal ablation technique that induces cell death by creating permanent cell membrane lysis through a short, high-voltage direct electrical current. Read more
Sustained Release of Eutectic systems composed of Local Anaesthetics and non-steroidal anti-inflammatory agents from biodegradable electrospun mats to Enhance Post-Surgical Recovery
Major abdominal surgery is a metabolically and psychologically significant event associated with prolonged recovery and convalescence. Read more
Bioactive, biodegradable coatings for urinary medical devices
The incidence of infection associated with indwelling medical devices is considerable and increases with the dwell time and location of the device. … Read more
Infection-responsive coatings for the prevention of catheter-associated urinary tract infections
Medical care has transformed over the last century with significant improvements in the variety and extent to which various diseases can be treated and/or prevented. Read more
Biomaterial coatings with lubricious, slippery coatings for improved urinary catheter performance
Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more
Development of dual-functional antibacterial and antifungal polymers to prevent medical device-associated infections
Medical device-related fungal infections caused by Candida spp., e.g., in urinary catheters, account for 17.8% of catheter-associated urinary tract infections, posing significant health risks, especially in individuals with compromised immunity. Read more
Smart, responsive biomaterials for infection-resistant medical devices
A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required. Read more
Improving antimicrobial delivery via nanoparticles
Antimicrobial resistant bacteria are a major issue, and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid antimicrobial drugs is by hiding within our own cells. Read more
Exploring the regulation of cancer cell movement by USP17
USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and high USP17 expression has been associated with tumour recurrence and spread (metastases) in several tumour types. Read more
Catalytic nanocages for in situ drug delivery
Therapeutic nanoreactors are innovative nanocompartments that confine one or more biocatalysts (e.g., enzymes) for the in-situ production of therapeutic agents, enabling targeted drug delivery with minimal off-site toxicity. Read more
Peptide-like hydrogels as long-acting injectable drug delivery platforms for the prevention of tuberculosis
Low to middle-income countries (LMIC) account for 95% of tuberculosis infections and deaths. Tuberculosis is currently the second highest infectious killer worldwide, after Covid-19, and is responsible for more deaths than HIV/AIDS. Read more
Peptide-like hydrogels as long-acting injectable drug delivery platforms for the prevention of malaria
There is an urgent need for new convenient drug delivery platforms to combat global health challenges in infectious disease, including malaria, and especially within low to middle-income countries (LMIC). Read more
Peptide-like hydrogels: A post-surgical sustained release drug delivery implant for the treatment of glioblastoma brain tumours
Glioblastoma is the most aggressive and malignant form of brain tumour with ~3,200 new cases annually within the UK and a median survival of 15 months. Read more
Access to medicines by older people in low and middle-income countries: a mixed methods study
Older people are the main consumers of medicines, and this is largely driven by multiple long-term conditions (multimorbidity). For some older people… Read more