One of the most challenging issues that the pharmaceutical industry face is poor aqueous solubility of drugs. 90% of candidate molecules within the discovery pipelines face solubility issues, posing significant hurdles to their clinical translation. Read more
The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more
The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more
Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more
Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more
Medical care has transformed over the last century with significant improvements in the variety and extent to which various diseases can be treated and/or prevented. Read more
Antibiotic-resistant bacteria are a growing problem in the 21st century, causing longer and more serious infections, and resulting in poor outcomes for vulnerable patients. . Read more
One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more
The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more
Cochlear implants are surgically implanted neuroprostheses designed to produce useful hearing sensations to persons with severe-to-profound sensorineural hearing loss by electrically stimulating the auditory nerve in the inner ear (or cochlea). Read more
It is estimated that there are close to 50 million people living with dementia worldwide, and this number is estimated to double every 20 years. Read more
Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more
Antimicrobial resistant bacteria are a growing problem and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid therapeutics is via intracellular infection, where they hide within our own cells. Read more
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