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Biochemistry PhD Projects, Programs & Scholarships

We have 765 Biochemistry PhD Projects, Programs & Scholarships

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We have 765 Biochemistry PhD Projects, Programs & Scholarships

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Evolution and engineering of non-ribosomal peptide synthetases (WILKINSON_J22DTP1)

The discovery & development of penicillin sparked ‘The Golden Age of Antibiotics’ which spanned the 1940’s to 1960’s when most major classes of antibiotics were discovered. Read more

Understanding Streptomyces cell division to improve antibiotic production (SCHLIMPERT_J22DTP)

Every cell must divide to grow and to propagate. While most bacteria simply split in half, the decision when and where to divide is more complex in multicellular bacteria like the antibiotic producing soil bacteria Streptomyces. Read more

Deciphering the in vivo RNA structure code in regulating protein translation in plants (DING_J22DTP2)

Codon optimisation is a common method in synthetic biology to achieve high levels of protein expression. It relies on the creation of so-called “silent” or synonymous mutations within a coding sequence, such that the DNA/RNA sequence is altered but the resulting amino acid sequence remains unchanged. Read more

Investigating how Plants use RNA to Cope with Stress (DING_J22DTP1)

The diversity of RNA structure is wide and varied, from hairpins and bulges through to triplex and quadruplexes. These structures are able to control numerous biological functions from sensing of messenger compounds to dictating whether genes are switched on or off. Read more

Control of Cell Polarity in Plants (COEN_J22DTP)

Cell polarity is fundamental for growth and division in plants. The BASL protein is localised to one end of stomatal precursors and plays a critical role in asymmetric division and stomatal spacing. Read more

Engineering enhanced vitamin synthesis in bacteria (WARRENM_Q22CASE)

This project aims to apply synthetic biology and metabolic engineering strategies to one of the most complex biochemical pathways found in nature in order to address a current need for a cheaper and more reliable source of vitamin B12, the so-called anti-pernicious anaemia factor. Read more

Are bacteria building toxic biofilms in your gut? (NARBAD_Q22DTP2)

Think of a corroded pipe. Now think of an inflamed gut. These conditions may be caused by similar bacteria. Sulphate reducing bacteria (SRB) are anaerobic bacteria, common in the environment and the gastrointestinal tract. Read more

Can we use bacteriocins to improve gut health? (NARBAD_Q22DTP1)

Many bacteria produce antimicrobial compounds to help them compete in mixed communities. Antimicrobial peptides called bacteriocins from food and dairy strains have already been exploited successfully to prevent food poisoning or mastitis. Read more

*Eastbio*: Serum albumin glycation and its impact on Zn2+-dependent haemostasis and insulin dynamics

Zinc is an essential micronutrient in mammals, vital to virtually all physiological pathways and processes. High nanomolar concentrations of free zinc ions (Zn2+) are cytotoxic; therefore, extracellular zinc is usually well-buffered. Read more

Using our expertise to develop future scientists - BHF Four Year Programme

Soon, 1 in 10 UK adults will have diabetes. In spite of modern treatments, most of these people will suffer major cardiovascular problems, including heart attack and stroke, impairing their quality of life and survival. Read more

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